TGF-β3-null mutation does not abrogate fetal lung maturation in vivo by glucocorticoids

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 277, Issue 6 21-6, 1999, Pages

  Shi, Wei ^a   Heisterkamp, Nora ^a   Groffen, John ^a   Zhao, Jingsong ^b   Warburton, David ^a,b   Kaartinen, Vesa ^a,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

Transforming growth factor 3; Tropoelastin expression

Indexed keywords

FIBRONECTIN; GLUCOCORTICOID; SURFACTANT PROTEIN C; TRANSFORMING GROWTH FACTOR BETA3; TROPOELASTIN; DEXAMETHASONE; LUNG SURFACTANT; MESSENGER RNA; PROTEOLIPID; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FETUS; FETUS LUNG; FETUS LUNG MATURATION; GENOTYPE; IN VIVO STUDY; KNOCKOUT MOUSE; LUNG FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEROID THERAPY; ANIMAL; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LUNG; MALE; MOUSE MUTANT; MUTAGENESIS; PHYSIOLOGY; PRENATAL DEVELOPMENT;

ANIMALS; CELL DIFFERENTIATION; DEXAMETHASONE; EPITHELIAL CELLS; FEMALE; FETUS; FIBRONECTINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOCORTICOIDS; LUNG; MALE; MICE; MICE, KNOCKOUT; MUTAGENESIS; PROTEOLIPIDS; PULMONARY SURFACTANTS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TROPOELASTIN;

EID: 0033252009     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.6.l1205     Document Type: Article

References (42)

1. Ballard, P. L., R. Ertsey, L. W. Gonzales, and J. Gonzales. Transcriptional regulation of human pulmonary surfactant proteins SP-B and SP-C by glucocorticoids. Am. J. Respir. Cell Mol. Biol. 14: 599-607, 1996.
2. Bellusci, S., J. Grindley, H. Emoto, N. Itoh, and B. L. Hogan. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124: 4867-4878, 1997.
3. Bellusci, S., R. Henderson, G. Winnier, T. Oikawa, and B. L. Hogan. Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development 122: 1693-1702, 1996.
4. Connelly, I. H., G. L. Hammond, P. G. Harding, and F. Possmayer. Levels of surfactant-associated protein messenger ribonucleic acids in rabbit lung during perinatal development and after hormonal treatment. Endocrinology 129: 2583-2591, 1991.
5. Grummer, M. A., and R. D. Zachman. Retinoic acid and dexamethasone affect RAR-β and surfactant protein C mRNA in the MLE lung cell line. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L1-L7, 1998.
6. Hilfer, S. R. Morphogenesis of the lung: control of embryonic and fetal branching. Annu. Rev. Physiol. 58: 93-113, 1996.
7. Ingber, D. E. Fibronectin controls capillary endothelial cell growth by modulating cell shape. Proc. Natl. Acad. Sci. USA 87: 3579-3583, 1990.
8. Ingber, D. E., and J. Folkman. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. J. Cell Biol. 109: 317-330, 1989.
9. Kaartinen, V., J. W. Voncken, C. Shuler, D. Warburton, D. Bu, N. Heisterkamp, and J. Groffen. Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction. Nat. Genet. 11: 415-421, 1995.
10. Kirkwood, B. Non-parametric methods. In: Medical Statistics. Oxford: Blackwell Scientific, 1988, p. 150-151.
11. Kulkarni, A. B., C. G. Huh, D. Becker, A. Geiser, M. Lyght, K. C. Flanders, A. B. Roberts, M. B. Sporn, J. M. Ward, and S. Karlsson. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA 90: 770-774, 1993.
12. Letterio, J. J., A. G. Geiser, A. B. Kulkarni, N. S. Roche, M. B. Sporn, and A. B. Roberts. Maternal rescue of transforming growth factor-beta 1 null mice. Science 264: 1936-1938, 1994.
13. Lindahl, P., L. Karlsson, M. Hellstrom, S. Gebre-Medhin, K. Willetts, J. K. Heath, and C. Betsholtz. Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development 124: 3943-3953, 1997.
14. Mallory, F. Pathological Technique. New York: Hafner, 1961, p. 169.
15. Maniscalco, W. M., R. A. Sinkin, R. H. Watkins, and M. H. Campbell. Transforming growth factor-beta 1 modulates type II cell fibronectin and surfactant protein C expression. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L569-L577, 1994.
16. Mariani, T. J., S. Sandefur, and R. A. Pierce. Elastin in lung development. Exp. Lung Res. 23: 131-145, 1997.
17. Miettinen, P. J., J. E. Berger, J. Meneses, Y. Phung, R. A. Pedersen, Z. Werb, and R. Derynck. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 376: 337-341, 1995.
18. Muglia, L., P. Jacobson, P. Dikkes, and J. A. Majzoub. Corticotropin-releasing hormone-deficiency reveals major fetal but not adult glucocorticoid need. Nature 373: 427-432, 1995.
19. Muglia, L. J., D. S. Bae, T. T. Brown, S. K. Vogt, J. G. Alvarez, M. E. Sunday, and J. A. Majzoub. Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am. J. Respir. Cell Mol. Biol. 20: 181-188, 1999.
20. Proetzel, G., S. A. Pawlowski, M. V. Wiles, M. Yin, G. P. Boivin, P. N. Howles, J. Ding, M. W. Ferguson, and T. Doetschman. Transforming growth factor-beta 3 is required for secondary palate fusion. Nat. Genet. 11: 409-414, 1995.
21. Roberts, A. B., and M. B. Sporn. The transforming growth factor βs. In: Peptide Growth Factors and Their Receptors, edited by M. B. Sporn and A. B. Roberts. Heidelberg, Germany: Springer-Verlag, 1991, p. 419-472.
22. Roberts, A. B., and M. B. Sporn. Differential expression of the TGF-beta isoforms in embryogenesis suggests specific roles in developing and adult tissues. Mol. Reprod. Dev. 32: 91-98, 1992.
23. Roman, J. Fibronectin and fibronectin receptors in lung development. Exp. Lung Res. 23: 147-159, 1997.
24. Roman, J., E. C. Crouch, and J. A. McDonald. Reagents that inhibit fibronectin matrix assembly of cultured cells also inhibit lung branching morphogenesis in vitro. Implications for lung development, injury, and repair. Chest 99: 20S-21S, 1991.
25. Roman, J., C. W. Little, and J. A. McDonald. Potential role of RGD-binding integrins in mammalian lung branching morphogenesis. Development 112: 551-558, 1991.
26. Sanford, L. P., I. Ormsby, A. C. Gittenberger-de Groot, H. Sariola, R. Friedman, G. P. Boivin, E. L. Cardell, and T. Doetschman. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 124: 2659-2670, 1997.
27. Schellhase, D. E. Pediatric flexible airway endoscopy - the light in the tunnel. J. Ark. Med. Soc. 91: 227-235, 1994.
28. Serra, R., and H. L. Moses. pRb is necessary for inhibition of N-myc expression by TGF-beta 1 in embryonic lung organ cultures. Development 121: 3057-3066, 1995.
29. Serra, R., R. W. Pelton, and H. L. Moses. TGF beta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development 120: 2153-2161, 1994.
30. Shiratori, M., E. Oshika, L. P. Ung, G. Singh, H. Shinozuka, D. Warburton, G. Michalopoulos, and S. L. Katyal. Keratinocyte growth factor and embryonic rat lung morphogenesis. Am. J. Respir. Cell Mol. Biol. 15: 328-338, 1996.
31. Shull, M. M., I. Ormsby, A. B. Kier, S. Pawlowski, R. J. Diebold, M. Yin, R. Allen, C. Sidman, G. Proetzel, D. Calvin, N. Annunziata, and T. Doetschman. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359: 693-699, 1992.
32. Ten Have-Opbroek, A. A. Lung development in the mouse embryo. Exp. Lung Res. 17: 111-130, 1991.
33. Venkatesh, V. C., D. M. Iannuzzi, R. Ertsey, and P. L. Ballard. Differential glucocorticoid regulation of the pulmonary hydrophobic surfactant proteins SP-B and SP-C. Am. J. Respir. Cell Mol. Biol. 8: 222-228, 1993.
34. Vorbroker, D. K., W. F. Voorhout, T. E. Weaver, and J. A. Whitsett. Posttranslational processing of surfactant protein C in rat type II cells. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L727-L733, 1995.
35. Wang, J., M. Kuliszewski, W. Yee, L. Sedlackova, J. Xu, I. Tseu, and M. Post. Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3. J. Biol. Chem. 270: 2722-2728, 1995.
36. Warburton, D., and B. E. Olver. Coordination of genetic, epigenetic, and environmental factors in lung development, injury, and repair. Chest 111: 119S-122S, 1997.
37. Whitsett, J. A., T. E. Weaver, M. A. Lieberman, J. C. Clark, and C. Daugherty. Differential effects of epidermal growth factor and transforming growth factor-beta on synthesis of Mr = 35,000 surfactant-associated protein in fetal lung. J. Biol. Chem. 262: 7908-7913, 1987.
38. Willet, K. E., P. McMenamin, K. E. Pinkerton, M. Ikegami, A. H. Jobe, L. Gurrin, and P. D. Sly. Lung morphometry and collagen and elastin content: changes during normal development and after prenatal hormone exposure in sheep. Pediatr. Res. 45: 615-625, 1999.
39. Wuenschell, C. W., J. Zhao, J. D. Tefft, and D. Warburton. Nicotine stimulates branching and expression of SP-A and SP-C mRNAs in embryonic mouse lung culture. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L165-L170, 1998.
40. Yee, W., J. Wang, J. Liu, I. Tseu, M. Kuliszewski, and M. Post. Glucocorticoid-induced tropoelastin expression is mediated via transforming growth factor-β3. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L992-L1001, 1996.
41. Zhao, J., D. Bu, M. Lee, H. C. Slavkin, F. L. Hall, and D. Warburton. Abrogation of transforming growth factor-beta type II receptor stimulates embryonic mouse lung branching morphogenesis in culture. Dev. Biol. 180: 242-257, 1996.
42. Zhou, L., C. R. Dey, S. E. Wert, and J. A. Whitsett. Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-beta 1 chimeric gene. Dev. Biol. 175: 227-238, 1996.