-
1
-
-
0035025093
-
Progress in the development of alternative pharmaceutical formulations of taxanes
-
B. Nuijen, M. Bouma, J.H.M. Schellens, and J.H. Beijnen Progress in the development of alternative pharmaceutical formulations of taxanes Invest. New Drugs 19 2 2001 143 153
-
(2001)
Invest. New Drugs
, vol.19
, Issue.2
, pp. 143-153
-
-
Nuijen, B.1
Bouma, M.2
Schellens, J.H.M.3
Beijnen, J.H.4
-
2
-
-
84871919918
-
Oral delivery of anti-cancer drugs I: General considerations
-
S. Mazzaferro, K. Bouchemal, G. Ponchel. Oral delivery of anti-cancer drugs I: General considerations, Drug. Discov. Today, http://dx.doi.org/10.1016/ j.drudis.2012.08.004.
-
Drug. Discov. Today.
-
-
Mazzaferro, S.1
Bouchemal, K.2
Ponchel, G.3
-
3
-
-
0036829187
-
Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir
-
H.A. Bardelmeijer, M. Ouwehand, T. Buckle, M.T. Huisman, J.H.M. Schellens, J.H. Beijnen, and O. van Tellingen Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir Cancer Res. 62 21 2002 6158 6164
-
(2002)
Cancer Res.
, vol.62
, Issue.21
, pp. 6158-6164
-
-
Bardelmeijer, H.A.1
Ouwehand, M.2
Buckle, T.3
Huisman, M.T.4
Schellens, J.H.M.5
Beijnen, J.H.6
Van Tellingen, O.7
-
4
-
-
80051793564
-
Bivalent sequential binding of docetaxel to methyl-ß-cyclodextrin
-
S. Mazzaferro, K. Bouchemal, J.-F. Gallard, B.I. Iorga, M. Cheron, C. Gueutin, C. Steinmesse, and G. Ponchel Bivalent sequential binding of docetaxel to methyl-ß-cyclodextrin Int. J. Pharm. 416 1 2011 171 180
-
(2011)
Int. J. Pharm.
, vol.416
, Issue.1
, pp. 171-180
-
-
Mazzaferro, S.1
Bouchemal, K.2
Gallard, J.-F.3
Iorga, B.I.4
Cheron, M.5
Gueutin, C.6
Steinmesse, C.7
Ponchel, G.8
-
5
-
-
0035865162
-
Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel
-
M.M. Malingré, D.J. Richel, J.H. Beijnen, H. Rosing, F.J. Koopman, W.W. Ten Bokkel Huinink, M.E. Schot, and J.H.M. Schellens Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel J. Clin. Oncol. 19 4 2001 1160 1166
-
(2001)
J. Clin. Oncol.
, vol.19
, Issue.4
, pp. 1160-1166
-
-
Malingré, M.M.1
Richel, D.J.2
Beijnen, J.H.3
Rosing, H.4
Koopman, F.J.5
Ten Bokkel Huinink, W.W.6
Schot, M.E.7
Schellens, J.H.M.8
-
6
-
-
67549142429
-
Coadministration of ritonavir strongly enhances the apparent oral bioavailability of docetaxel in patients with solid tumors
-
R.L. Oostendorp, A. Huitema, H. Rosing, R.S. Jansen, R. Ter Heine, M. Keessen, J.H. Beijnen, and J.H.M. Schellens Coadministration of ritonavir strongly enhances the apparent oral bioavailability of docetaxel in patients with solid tumors Clin. Cancer Res. 15 12 2009 4228 4233
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.12
, pp. 4228-4233
-
-
Oostendorp, R.L.1
Huitema, A.2
Rosing, H.3
Jansen, R.S.4
Ter Heine, R.5
Keessen, M.6
Beijnen, J.H.7
Schellens, J.H.M.8
-
7
-
-
80054697562
-
Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)
-
J.J. Moes, S.L.W. Koolen, A.D.R. Huitema, J.H.M. Schellens, J.H. Beijnen, and B. Nuijen Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001) Int. J. Pharm. 420 2 2011 244 250
-
(2011)
Int. J. Pharm.
, vol.420
, Issue.2
, pp. 244-250
-
-
Moes, J.J.1
Koolen, S.L.W.2
Huitema, A.D.R.3
Schellens, J.H.M.4
Beijnen, J.H.5
Nuijen, B.6
-
8
-
-
70350618790
-
Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation
-
Y.-M. Yin, F.-D. Cui, C.-F. Mu, M.-K. Choi, J.S. Kim, S.-J. Chung, C.-K. Shim, and D.-D. Kim Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation J. Control. Release 140 2 2009 86 94
-
(2009)
J. Control. Release
, vol.140
, Issue.2
, pp. 86-94
-
-
Yin, Y.-M.1
Cui, F.-D.2
Mu, C.-F.3
Choi, M.-K.4
Kim, J.S.5
Chung, S.-J.6
Shim, C.-K.7
Kim, D.-D.8
-
9
-
-
70350622459
-
In vivo antitumor effects of chitosan-conjugated docetaxel after oral administration
-
E. Lee, H. Kim, I.-H. Lee, and S. Jon In vivo antitumor effects of chitosan-conjugated docetaxel after oral administration J. Control. Release 140 2 2009 79 85
-
(2009)
J. Control. Release
, vol.140
, Issue.2
, pp. 79-85
-
-
Lee, E.1
Kim, H.2
Lee, I.-H.3
Jon, S.4
-
10
-
-
84862682798
-
The counterbalanced effect of size and surface properties of chitosan-coated poly(isobutylcyanoacrylate) nanoparticle on mucoadhesion due to pluronic F68 addition
-
B. Petit, K. Bouchemal, C. Vauthier, M. Djabourov, and G. Ponchel The counterbalanced effect of size and surface properties of chitosan-coated poly(isobutylcyanoacrylate) nanoparticle on mucoadhesion due to pluronic F68 addition Pharm. Res. 29 2012 943 952
-
(2012)
Pharm. Res.
, vol.29
, pp. 943-952
-
-
Petit, B.1
Bouchemal, K.2
Vauthier, C.3
Djabourov, M.4
Ponchel, G.5
-
11
-
-
33846799473
-
Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles
-
I. Bravo-Osuna, C. Vauthier, A. Farabollini, G.F. Palmieri, and G. Ponchel Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles Biomaterials 28 13 2007 2233 2243
-
(2007)
Biomaterials
, vol.28
, Issue.13
, pp. 2233-2243
-
-
Bravo-Osuna, I.1
Vauthier, C.2
Farabollini, A.3
Palmieri, G.F.4
Ponchel, G.5
-
12
-
-
84874553481
-
Reduced intestinal toxicity of docetaxel into mucoadhesive nanoparticles, in mouse xenograft model
-
(in press)
-
S. Mazzaferro, K. Bouchemal, A. Maksimenko, R. Skanji, P. Opolon, G. Ponchel, Reduced intestinal toxicity of docetaxel into mucoadhesive nanoparticles, in mouse xenograft model. J. Colloid. Sci. Biotechnol. (in press).
-
J. Colloid. Sci. Biotechnol.
-
-
Mazzaferro, S.1
Bouchemal, K.2
Maksimenko, A.3
Skanji, R.4
Opolon, P.5
Ponchel, G.6
-
13
-
-
33344454616
-
Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine
-
M. Werle, and M. Hoffer Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine J. Control. Release 111 1-2 2006 41 46
-
(2006)
J. Control. Release
, vol.111
, Issue.12
, pp. 41-46
-
-
Werle, M.1
Hoffer, M.2
-
14
-
-
33646814008
-
Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles
-
I. Bravo-Osuna, T. Schmitz, A. Bernkop-Schnürch, C. Vauthier, and G. Ponchel Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles Int. J. Pharm. 316 1-2 2006 170 175
-
(2006)
Int. J. Pharm.
, vol.316
, Issue.12
, pp. 170-175
-
-
Bravo-Osuna, I.1
Schmitz, T.2
Bernkop-Schnürch, A.3
Vauthier, C.4
Ponchel, G.5
-
15
-
-
57749184307
-
A new approach to determine loading efficiency of Leu-enkephalin in poly(isobutylcyanoacrylate) nanoparticles coated with thiolated chitosan
-
K. Bouchemal, G. Ponchel, S. Mazzaferro, V.-H. Campos-requena, C. Gueutin, G.-F. Palmieri, and C. Vauthier A new approach to determine loading efficiency of Leu-enkephalin in poly(isobutylcyanoacrylate) nanoparticles coated with thiolated chitosan J. Drug Del. Sci. Technol. 18 6 2008 392 397
-
(2008)
J. Drug Del. Sci. Technol.
, vol.18
, Issue.6
, pp. 392-397
-
-
Bouchemal, K.1
Ponchel, G.2
Mazzaferro, S.3
Campos-Requena, V.-H.4
Gueutin, C.5
Palmieri, G.-F.6
Vauthier, C.7
-
16
-
-
0347090152
-
Combined poly(isobutylcyanoacrylate) and cyclodextrins nanoparticles for enhancing the encapsulation of lipophilic drugs
-
A. Monza da Silveira, G. Ponchel, F. Puisieux, and D. Duchêne Combined poly(isobutylcyanoacrylate) and cyclodextrins nanoparticles for enhancing the encapsulation of lipophilic drugs Pharm. Res. 15 7 1998 1051 1055
-
(1998)
Pharm. Res.
, vol.15
, Issue.7
, pp. 1051-1055
-
-
Monza Da Silveira, A.1
Ponchel, G.2
Puisieux, F.3
Duchêne, D.4
-
17
-
-
77957760524
-
-
WO Patent
-
A. Monza Da Silveira, G. Ponchel, D. Duchene, P. Couvreur, F. Puisieux, Nanoparticles comprising polyisobutylcyanocrilate and cyclodextrins, WO Patent, 1999.
-
(1999)
Nanoparticles Comprising Polyisobutylcyanocrilate and Cyclodextrins
-
-
Monza Da Silveira, A.1
Ponchel, G.2
Duchene, D.3
Couvreur, P.4
Puisieux, F.5
-
18
-
-
0033911983
-
Insulin loaded nanocapsules for oral administration: In vitro and in vivo investigation
-
M. Aboubakar, P. Couvreur, H. Pinto-Alphandary, B. Gouritin, B. Lacour, R. Farinotti, F. Puisieux, and C. Vauthier Insulin loaded nanocapsules for oral administration: in vitro and in vivo investigation Drug Dev. Res. 49 2000 109 117
-
(2000)
Drug Dev. Res.
, vol.49
, pp. 109-117
-
-
Aboubakar, M.1
Couvreur, P.2
Pinto-Alphandary, H.3
Gouritin, B.4
Lacour, B.5
Farinotti, R.6
Puisieux, F.7
Vauthier, C.8
-
19
-
-
70349840419
-
Combined hydroxypropyl-[beta]-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel
-
M. Agüeros, L. Ruiz-Gatón, C. Vauthier, K. Bouchemal, S. Espuelas, G. Ponchel, and J. Irache Combined hydroxypropyl-[beta]-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel Eur. J. Pharm. Sci. 38 4 2009 405 413
-
(2009)
Eur. J. Pharm. Sci.
, vol.38
, Issue.4
, pp. 405-413
-
-
Agüeros, M.1
Ruiz-Gatón, L.2
Vauthier, C.3
Bouchemal, K.4
Espuelas, S.5
Ponchel, G.6
Irache, J.7
-
20
-
-
0035073634
-
The intestinal mucus protects poly(isobutylcyanoacrylate) nanoparticles from enzymatic degradation
-
A. Dembri, D. Duchêne, and G. Ponchel The intestinal mucus protects poly(isobutylcyanoacrylate) nanoparticles from enzymatic degradation STP Pharm. Sci. 11 2 2001 175 180
-
(2001)
STP Pharm. Sci.
, vol.11
, Issue.2
, pp. 175-180
-
-
Dembri, A.1
Duchêne, D.2
Ponchel, G.3
-
21
-
-
35349012642
-
Animal data: The contributions of the Ussing chamber and perfusion systems to predicting human oral drug delivery in vivo
-
H. Lennernäs Animal data: the contributions of the Ussing chamber and perfusion systems to predicting human oral drug delivery in vivo Adv. Drug Deliv. Rev. 59 11 2007 1103 1120
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
, Issue.11
, pp. 1103-1120
-
-
Lennernäs, H.1
-
22
-
-
49249137213
-
Enhanced oral bioavailability of doxorubicin in a dendrimer drug delivery system
-
W. Ke, Y. Zhao, R. Huang, C. Jiang, and Y. Pei Enhanced oral bioavailability of doxorubicin in a dendrimer drug delivery system J. Pharm. Sci. 97 6 2008 2208 2216
-
(2008)
J. Pharm. Sci.
, vol.97
, Issue.6
, pp. 2208-2216
-
-
Ke, W.1
Zhao, Y.2
Huang, R.3
Jiang, C.4
Pei, Y.5
-
23
-
-
20744447950
-
Enhanced oral paclitaxel absorption with vitamin E-TPGS: Effect on solubility and permeability in vitro, in situ and in vivo
-
M.V.S. Varma, and R. Panchagnula Enhanced oral paclitaxel absorption with vitamin E-TPGS: effect on solubility and permeability in vitro, in situ and in vivo Eur. J. Pharm. Sci. 25 4-5 2005 445 453
-
(2005)
Eur. J. Pharm. Sci.
, vol.25
, Issue.45
, pp. 445-453
-
-
Varma, M.V.S.1
Panchagnula, R.2
-
24
-
-
11244321887
-
Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093)
-
I.E.L.M. Kuppens, T.M. Bosch, M.J. Maanen, H. Rosing, A. Fitzpatrick, J.H. Beijnen, and J.H.M. Schellens Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093) Cancer Chemother. Pharm. 55 1 2005 72 78
-
(2005)
Cancer Chemother. Pharm.
, vol.55
, Issue.1
, pp. 72-78
-
-
Kuppens, I.E.L.M.1
Bosch, T.M.2
Maanen, M.J.3
Rosing, H.4
Fitzpatrick, A.5
Beijnen, J.H.6
Schellens, J.H.M.7
-
25
-
-
0036909078
-
Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: An overview
-
C. Kruijtzer, J. Beijnen, and J. Schellens Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview Oncologist 7 6 2002 516 530
-
(2002)
Oncologist
, vol.7
, Issue.6
, pp. 516-530
-
-
Kruijtzer, C.1
Beijnen, J.2
Schellens, J.3
-
26
-
-
4644237728
-
Permeability of human jejunal segments to gonyautoxins measured by the Ussing chamber technique
-
P. Mardones, D. Andrinolo, A. Csendes, and N. Lagos Permeability of human jejunal segments to gonyautoxins measured by the Ussing chamber technique Toxicon 44 5 2004 521 528
-
(2004)
Toxicon
, vol.44
, Issue.5
, pp. 521-528
-
-
Mardones, P.1
Andrinolo, D.2
Csendes, A.3
Lagos, N.4
-
27
-
-
33644797560
-
Methylated β-cyclodextrin as P-gp modulators for deliverance of doxorubicin across an in vitro model of blood-brain barrier
-
S. Tilloy, V. Monnaert, L. Fenart, H. Bricout, R. Cecchelli, and E. Monflier Methylated β-cyclodextrin as P-gp modulators for deliverance of doxorubicin across an in vitro model of blood-brain barrier Bioorg. Med. Chem. Lett. 16 2006 2154 2157
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 2154-2157
-
-
Tilloy, S.1
Monnaert, V.2
Fenart, L.3
Bricout, H.4
Cecchelli, R.5
Monflier, E.6
-
28
-
-
0031916195
-
In vitro modulation of doxorubicin and docetaxel antitumoral activity by methyl-beta-cyclodextrin
-
P.Y. Grosse, F. Bressolle, and F. Pinguet In vitro modulation of doxorubicin and docetaxel antitumoral activity by methyl-beta-cyclodextrin Eur. J. Cancer 34 1 1998 168 174
-
(1998)
Eur. J. Cancer
, vol.34
, Issue.1
, pp. 168-174
-
-
Grosse, P.Y.1
Bressolle, F.2
Pinguet, F.3
-
29
-
-
38349162946
-
Polymeric and low molecular mass efflux pump inhibitors for oral drug delivery
-
M. Werle Polymeric and low molecular mass efflux pump inhibitors for oral drug delivery J. Pharm. Sci. 97 2007 60 70
-
(2007)
J. Pharm. Sci.
, vol.97
, pp. 60-70
-
-
Werle, M.1
-
30
-
-
33747831750
-
In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein
-
F. Föger, H. Hoyer, K. Kafedjiiski, M. Thaurer, and A. Bernkop-Schnürch In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein Biomaterials 27 34 2006 5855 5860
-
(2006)
Biomaterials
, vol.27
, Issue.34
, pp. 5855-5860
-
-
Föger, F.1
Hoyer, H.2
Kafedjiiski, K.3
Thaurer, M.4
Bernkop-Schnürch, A.5
|