Influence of molecular shape, conformability, net surface charge, and tissue interaction on transscleral macromolecular diffusion

Experimental Eye Research

Volumn 102, Issue , 2012, Pages 85-92

  Srikantha, Nishanthan ^a   Mourad, Fatma ^a   Suhling, Klaus ^a   Elsaid, Naba ^b   Levitt, James ^a   Chung, Pei Hua ^a   Somavarapu, Satyanarayana ^b   Jackson, Timothy L ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Diffusion; Fluorescence recovery after photobleaching (FRAP); Molecular conformability; Molecular shape; Posterior segment drug delivery; Retinal disease; Transscleral diffusion

Indexed keywords

ALBUMIN; DEXTRAN; FICOLL;

ARTICLE; DIFFUSION; DIFFUSION COEFFICIENT; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; MOLECULAR CONFORMABILITY; MOLECULAR SHAPE; NET SURFACE CHARGE; PHYSICAL PARAMETERS; PRIORITY JOURNAL; SPECTROPHOTOMETRY; TISSUE INTERACTION; TRANSSCLERAL DIFFUSION;

ANIMALS; DEXTRANS; DIFFUSION; DIFFUSION CHAMBERS, CULTURE; FICOLL; FLUORESCEIN-5-ISOTHIOCYANATE; LASER-DOPPLER FLOWMETRY; LIGHT; MOLECULAR WEIGHT; MULTIPROTEIN COMPLEXES; PERMEABILITY; PROTEIN CONFORMATION; SCATTERING, RADIATION; SCLERA; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE; SWINE;

EID: 84865589560     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2012.07.007     Document Type: Article

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