Paclitaxel-conjugated PEG and arginine-grafted bioreducible poly (disulfide amine) micelles for co-delivery of drug and gene

Biomaterials

Volumn 33, Issue 32, 2012, Pages 8122-8130

  Nam, Kihoon ^a   Nam, Hye Yeong ^a   Kim, Pyung Hwan ^a   Kim, Sung Wan ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Bioreducible polymer; Drug delivery; Gene therapy; Interleukin 12; Paclitaxel; Polymeric micelle

Indexed keywords

AVERAGE SIZE; BIOREDUCIBLE POLYMER; CELLULAR UPTAKE; CRITICAL MICELLE CONCENTRATION (CMC); DELIVERY SYSTEMS; GENE DELIVERY; INTERLEUKIN-12; LUCIFERASE GENES; PACLITAXEL; PLASMID DNA; POLYMERIC MICELLE; POLYPLEXES; POSITIVE SURFACE CHARGE; SELF-ASSEMBLED; UV ABSORPTION;

ARGININE; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY; GENE THERAPY; GENE TRANSFER; GENES; GRAFTING (CHEMICAL); MICELLES; POLYETHYLENE OXIDES; ZETA POTENTIAL;

POLYETHYLENE GLYCOLS;

ARGININE; INTERLEUKIN 12; LUCIFERASE; MACROGOL; PACLITAXEL; PACLITAXEL MACROGOL POLY(CYSTAMINEBISACRYLAMIDE DIAMINOHEXANE)ARGININE CONJUGATE; PLASMID DNA; POLY(CYSTAMINEBISACRYLAMIDE DIAMINOHEXANE)ARGININE; POLYAMINE DERIVATIVE; PYRENE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG POTENCY; DRUG UPTAKE; GENE DELIVERY SYSTEM; HUMAN; HUMAN CELL; MICELLE; PARTICLE SIZE; PRIORITY JOURNAL; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARGININE; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA; FEMALE; GLUTATHIONE; HUMANS; INTERLEUKIN-12; MICE; MICELLES; PACLITAXEL; PARTICLE SIZE; POLYAMINES; POLYETHYLENE GLYCOLS; TRANSFECTION;

EID: 84865561825     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.07.031     Document Type: Article

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