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Volumn 32, Issue 8, 2012, Pages 617-625

Genistein promotes insulin action through adenosine monophosphate-activated protein kinase activation and p70 ribosomal protein S6 kinase 1 inhibition in the skeletal muscle of mice fed a high energy diet

Author keywords

AMP activated protein kinase; Genistein; High fat high fructose diet; Insulin signaling; Mice; P70 ribosomal protein S6 kinase 1; Skeletal muscle

Indexed keywords

ACETYL COENZYME A; ADENYLATE KINASE; GENISTEIN; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; SERINE; TYROSINE; UNCLASSIFIED DRUG;

EID: 84865558849     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2012.06.002     Document Type: Article
Times cited : (36)

References (41)
  • 1
    • 77953165944 scopus 로고    scopus 로고
    • Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet
    • Wada T., Kenmochi H., Miyashita Y., Sasaki M., Ojima M., Sasahara M., et al. Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet. Endocrinology 2010, 151:2040-2049.
    • (2010) Endocrinology , vol.151 , pp. 2040-2049
    • Wada, T.1    Kenmochi, H.2    Miyashita, Y.3    Sasaki, M.4    Ojima, M.5    Sasahara, M.6
  • 2
    • 33749239623 scopus 로고    scopus 로고
    • The metabolic syndrome: role of skeletal muscle metabolism
    • Stump C.S., Henriksen E.J., Wei Y., Sowers J.R. The metabolic syndrome: role of skeletal muscle metabolism. Ann Med 2006, 38:389-402.
    • (2006) Ann Med , vol.38 , pp. 389-402
    • Stump, C.S.1    Henriksen, E.J.2    Wei, Y.3    Sowers, J.R.4
  • 4
    • 0030029152 scopus 로고    scopus 로고
    • Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts
    • Edelmann H.M., Kühne C., Petritsch C., Ballou L.M. Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts. J Biol Chem 1996, 271:963-971.
    • (1996) J Biol Chem , vol.271 , pp. 963-971
    • Edelmann, H.M.1    Kühne, C.2    Petritsch, C.3    Ballou, L.M.4
  • 5
    • 48749105887 scopus 로고    scopus 로고
    • Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats
    • Ono H., Pocai A., Wang Y., Sakoda H., Asano T., Backer J.M., et al. Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats. J Clin Invest 2008, 118:2959-2968.
    • (2008) J Clin Invest , vol.118 , pp. 2959-2968
    • Ono, H.1    Pocai, A.2    Wang, Y.3    Sakoda, H.4    Asano, T.5    Backer, J.M.6
  • 6
    • 4544220704 scopus 로고    scopus 로고
    • Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
    • Um S.H., Frigerio F., Watanabe M., Picard F., Joaquin M., Sticker M., et al. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 2004, 431:200-205.
    • (2004) Nature , vol.431 , pp. 200-205
    • Um, S.H.1    Frigerio, F.2    Watanabe, M.3    Picard, F.4    Joaquin, M.5    Sticker, M.6
  • 7
    • 33744505375 scopus 로고    scopus 로고
    • Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
    • Um S.H., D'Alessio D., Thomas G. Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab 2006, 3:393-402.
    • (2006) Cell Metab , vol.3 , pp. 393-402
    • Um, S.H.1    D'Alessio, D.2    Thomas, G.3
  • 8
    • 33847080728 scopus 로고    scopus 로고
    • AMP-activated protein kinase in metabolic control and insulin signaling
    • Towler M.C., Hardie D.G. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 2007, 100:328-341.
    • (2007) Circ Res , vol.100 , pp. 328-341
    • Towler, M.C.1    Hardie, D.G.2
  • 9
    • 33745225026 scopus 로고    scopus 로고
    • AMP-activated protein kinase-development of the energy sensor concept
    • Hardie D.G., Hawley S.A., Scott J.W. AMP-activated protein kinase-development of the energy sensor concept. J Physiol 2006, 574:7-15.
    • (2006) J Physiol , vol.574 , pp. 7-15
    • Hardie, D.G.1    Hawley, S.A.2    Scott, J.W.3
  • 10
    • 65349177200 scopus 로고    scopus 로고
    • AMPK: an emerging drug target for diabetes and the metabolic syndrome
    • Zhang B.B., Zhou G., Li C. AMPK: an emerging drug target for diabetes and the metabolic syndrome. Cell Metab 2009, 9:407-416.
    • (2009) Cell Metab , vol.9 , pp. 407-416
    • Zhang, B.B.1    Zhou, G.2    Li, C.3
  • 11
    • 77949459392 scopus 로고    scopus 로고
    • AMPK exerts dual regulatory effects on the PI3K pathway
    • Tao R., Gong J., Luo X., Zang M., Guo W., Wen R., et al. AMPK exerts dual regulatory effects on the PI3K pathway. J Mol Signal 2010, 5:1-9.
    • (2010) J Mol Signal , vol.5 , pp. 1-9
    • Tao, R.1    Gong, J.2    Luo, X.3    Zang, M.4    Guo, W.5    Wen, R.6
  • 12
    • 34547742675 scopus 로고    scopus 로고
    • Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a two-year randomized, double-blind, placebo-controlled study
    • Atteritano M., Marini H., Minutoli L., Polito F., Bitto A., Altavilla D., et al. Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a two-year randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab 2007, 92:3068-3075.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3068-3075
    • Atteritano, M.1    Marini, H.2    Minutoli, L.3    Polito, F.4    Bitto, A.5    Altavilla, D.6
  • 13
    • 0001223839 scopus 로고    scopus 로고
    • Isoflavone and bone metabolism: its cellular mechanism and preventive role in bone loss
    • Yamaguchi M. Isoflavone and bone metabolism: its cellular mechanism and preventive role in bone loss. J Health Sci 2002, 48:209-222.
    • (2002) J Health Sci , vol.48 , pp. 209-222
    • Yamaguchi, M.1
  • 15
    • 77955056005 scopus 로고    scopus 로고
    • Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance
    • Mohamed Salih S., Nallasamy P., Muniyandi P., Periyasami V., Carani Venkatraman A. Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance. J Diabetes 2009, 1:278-287.
    • (2009) J Diabetes , vol.1 , pp. 278-287
    • Mohamed Salih, S.1    Nallasamy, P.2    Muniyandi, P.3    Periyasami, V.4    Carani Venkatraman, A.5
  • 17
    • 78149482135 scopus 로고    scopus 로고
    • The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease
    • Kim M.H., Kang K.S., Lee Y.S. The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease. Br J Nutr 2010, 104:1333-1342.
    • (2010) Br J Nutr , vol.104 , pp. 1333-1342
    • Kim, M.H.1    Kang, K.S.2    Lee, Y.S.3
  • 18
    • 84857331521 scopus 로고    scopus 로고
    • An intervention study in obese mice with astaxanthin, a marine carotenoid-effects on insulin signaling and pro-inflammatory cytokines
    • Arunkumar E., Bhuvaneswari S., Anuradha C.V. An intervention study in obese mice with astaxanthin, a marine carotenoid-effects on insulin signaling and pro-inflammatory cytokines. Food Funct 2012, 3:120-126.
    • (2012) Food Funct , vol.3 , pp. 120-126
    • Arunkumar, E.1    Bhuvaneswari, S.2    Anuradha, C.V.3
  • 19
    • 57049134614 scopus 로고    scopus 로고
    • Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats
    • Cacho J., Sevillano J., de Castro J., Herrera E., Ramos M.P. Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats. Am J Physiol Endocrinol Metab 2008, 295:E1269-E1276.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Cacho, J.1    Sevillano, J.2    de Castro, J.3    Herrera, E.4    Ramos, M.P.5
  • 20
    • 0034456568 scopus 로고    scopus 로고
    • Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans
    • Katz A., Nambi S.S., Mather K., Baron A.D., Follmann D.A., Sullivan G., et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000, 85:2402-2410.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2402-2410
    • Katz, A.1    Nambi, S.S.2    Mather, K.3    Baron, A.D.4    Follmann, D.A.5    Sullivan, G.6
  • 22
    • 15744394674 scopus 로고    scopus 로고
    • Fructose, insulin resistance, and metabolic dyslipidemia
    • Basciano H., Federico L., Adeli K. Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab (Lond) 2005, 2:1-14.
    • (2005) Nutr Metab (Lond) , vol.2 , pp. 1-14
    • Basciano, H.1    Federico, L.2    Adeli, K.3
  • 23
    • 0028023002 scopus 로고
    • Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling
    • Tanti J.F., Grémeaux T., van Obberghen E., Le Marchand-Brustel Y. Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. J Biol Chem 1994, 269:6051-6057.
    • (1994) J Biol Chem , vol.269 , pp. 6051-6057
    • Tanti, J.F.1    Grémeaux, T.2    van Obberghen, E.3    Le Marchand-Brustel, Y.4
  • 24
    • 11244280921 scopus 로고    scopus 로고
    • Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism
    • del Rincón S.V., Guo Q., Morelli C., Shiu H.Y., Surmacz E., Miller W.H. Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism. Oncogene 2004, 23:9269-9279.
    • (2004) Oncogene , vol.23 , pp. 9269-9279
    • del Rincón, S.V.1    Guo, Q.2    Morelli, C.3    Shiu, H.Y.4    Surmacz, E.5    Miller, W.H.6
  • 25
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
    • Aguirre V., Uchida T., Yenush L., Davis R., White M.F. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000, 275:9047-9054.
    • (2000) J Biol Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 26
    • 0037073679 scopus 로고    scopus 로고
    • Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex
    • Gao Z., Hwang D., Bataille F., Lefevre M., York D., Quon M.J., et al. Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex. J Biol Chem 2002, 277:48115-48121.
    • (2002) J Biol Chem , vol.277 , pp. 48115-48121
    • Gao, Z.1    Hwang, D.2    Bataille, F.3    Lefevre, M.4    York, D.5    Quon, M.J.6
  • 27
    • 0031465447 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
    • De Fea K., Roth R.A. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. J Biol Chem 1997, 272:31400-31406.
    • (1997) J Biol Chem , vol.272 , pp. 31400-31406
    • De Fea, K.1    Roth, R.A.2
  • 28
    • 0035957949 scopus 로고    scopus 로고
    • Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins
    • Liu Y.F., Paz K., Herschkovitz A., Alt A., Tennenbaum T., Sampson S.R., et al. Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins. J Biol Chem 2001, 276:14459-14465.
    • (2001) J Biol Chem , vol.276 , pp. 14459-14465
    • Liu, Y.F.1    Paz, K.2    Herschkovitz, A.3    Alt, A.4    Tennenbaum, T.5    Sampson, S.R.6
  • 29
    • 8544233570 scopus 로고    scopus 로고
    • Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)
    • Li Y., Soos T.J., Li X., Wu J., Degennaro M., Sun X., et al. Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). J Biol Chem 2004, 279:45304-45307.
    • (2004) J Biol Chem , vol.279 , pp. 45304-45307
    • Li, Y.1    Soos, T.J.2    Li, X.3    Wu, J.4    Degennaro, M.5    Sun, X.6
  • 30
    • 0034463918 scopus 로고    scopus 로고
    • A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1
    • Haruta T., Uno T., Kawahara J., Takano A., Egawa K., Sharma P.M., et al. A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. Mol Endocrinol 2000, 14:783-794.
    • (2000) Mol Endocrinol , vol.14 , pp. 783-794
    • Haruta, T.1    Uno, T.2    Kawahara, J.3    Takano, A.4    Egawa, K.5    Sharma, P.M.6
  • 31
    • 35348832340 scopus 로고    scopus 로고
    • Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
    • Tremblay F., BrÛlé S., Hee Um S., Li Y., Masuda K., Roden M., et al. Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance. Proc Natl Acad Sci USA 2007, 104:14056-14061.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14056-14061
    • Tremblay, F.1    Brûlé, S.2    Hee Um, S.3    Li, Y.4    Masuda, K.5    Roden, M.6
  • 34
    • 65649118867 scopus 로고    scopus 로고
    • Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways
    • Zhang M., Ikeda K., Xu J.W., Yamori Y., Gao X.M., Zhang B.L. Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways. Phytother Res 2009, 23:713-718.
    • (2009) Phytother Res , vol.23 , pp. 713-718
    • Zhang, M.1    Ikeda, K.2    Xu, J.W.3    Yamori, Y.4    Gao, X.M.5    Zhang, B.L.6
  • 35
    • 50249160525 scopus 로고    scopus 로고
    • Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity
    • Liao Q.C., Li Y.L., Qin Y.F., Quarles L.D., Xu K.K., Li R., et al. Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity. J Cell Biochem 2008, 104:1853-1864.
    • (2008) J Cell Biochem , vol.104 , pp. 1853-1864
    • Liao, Q.C.1    Li, Y.L.2    Qin, Y.F.3    Quarles, L.D.4    Xu, K.K.5    Li, R.6
  • 36
    • 27744455616 scopus 로고    scopus 로고
    • Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase
    • Hwang J.T., Park I.J., Shin J.I., Lee Y.K., Lee S.K., Baik H.W., et al. Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase. Biochem Biophys Res Commun 2005, 338:694-699.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 694-699
    • Hwang, J.T.1    Park, I.J.2    Shin, J.I.3    Lee, Y.K.4    Lee, S.K.5    Baik, H.W.6
  • 37
    • 0035861644 scopus 로고    scopus 로고
    • 5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside
    • Jakobsen S.N., Hardie D.G., Morrice N., Tornqvist H.E. 5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside. J Biol Chem 2001, 276:46912-46916.
    • (2001) J Biol Chem , vol.276 , pp. 46912-46916
    • Jakobsen, S.N.1    Hardie, D.G.2    Morrice, N.3    Tornqvist, H.E.4
  • 38
    • 34247265428 scopus 로고    scopus 로고
    • Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1
    • Wang C., Mao X., Wang L., Liu M., Wetzel M.D., Guan K.L., et al. Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1. J Biol Chem 2007, 282:7991-7996.
    • (2007) J Biol Chem , vol.282 , pp. 7991-7996
    • Wang, C.1    Mao, X.2    Wang, L.3    Liu, M.4    Wetzel, M.D.5    Guan, K.L.6
  • 40
    • 0345374578 scopus 로고    scopus 로고
    • Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity
    • Ruderman N.B., Saha A.K., Kraegen E.W. Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity. Endocrinology 2003, 144:5166-5171.
    • (2003) Endocrinology , vol.144 , pp. 5166-5171
    • Ruderman, N.B.1    Saha, A.K.2    Kraegen, E.W.3
  • 41
    • 79955487247 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
    • Holland W.L., Bikman B.T., Wang L.P., Yuguang G., Sargent K.M., Bulchand S., et al. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest 2011, 121:1858-1870.
    • (2011) J Clin Invest , vol.121 , pp. 1858-1870
    • Holland, W.L.1    Bikman, B.T.2    Wang, L.P.3    Yuguang, G.4    Sargent, K.M.5    Bulchand, S.6


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