Optimization of [ 11C]DASB-synthesis: Vessel-based and flow-through microreactor methods

Applied Radiation and Isotopes

Volumn 70, Issue 11, 2012, Pages 2615-2620

  Ungersboeck, Johanna ^a,b   Philippe, Cecile ^a,b   Haeusler, Daniela ^a   Mitterhauser, Markus ^a,b   Lanzenberger, Rupert ^a   Dudczak, Robert ^a   Wadsak, Wolfgang ^a,b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

11C methylation; Carbon 11; DASB; Microfluidic; PET

Indexed keywords

11C-METHYLATION; CARBON-11; DASB; FLOWTHROUGH; MICRO-REACTOR; MICROREACTOR DEVICES; TIME CONSUMPTION;

ALKYLATION; MICROFLUIDICS; POLYETHYLENE TEREPHTHALATES;

METHYLATION;

3 AMINO 4 (N METHYL N METHYL AMINOMETHYLPHENYLSULFANYL)BENZONITRILE C 11; DIMETHYL SULFOXIDE; METHYL IODIDE; METHYL IODIDE C 11; METHYL TRIFLATE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; 3 AMINO 4 (2 DIMETHYLAMINOMETHYLPHENYLSULFANYL)BENZONITRILE; 3-AMINO-4-(2-DIMETHYLAMINOMETHYLPHENYLSULFANYL)BENZONITRILE; ANILINE DERIVATIVE; BENZONITRILE; CARBON; NITRILE; SULFIDE;

ARTICLE; CHEMICAL ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHYLATION; MICROFLUIDICS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PURIFICATION; RADIOCHEMISTRY; REACTION TIME; SOLID PHASE EXTRACTION; SYNTHESIS; ISOTOPE LABELING; METHODOLOGY; POSITRON EMISSION TOMOGRAPHY;

ANILINE COMPOUNDS; CARBON RADIOISOTOPES; ISOTOPE LABELING; METHYLATION; MICROFLUIDICS; NITRILES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SULFIDES;

EID: 84865556444     PISSN: 09698043     EISSN: 18729800     Source Type: Journal    
DOI: 10.1016/j.apradiso.2012.08.001     Document Type: Article

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