Imaging the inhibition by anti-β1 integrin antibody of lung seeding of single osteosarcoma cells in live mice

International Journal of Cancer

Volumn 131, Issue 9, 2012, Pages 2027-2033

  Kimura, Hiroaki ^a,b,c   Tome, Yasunori ^a,b   Momiyama, Masashi ^a,b   Hayashi, Katsuhiro ^c   Tsuchiya, Hiroyuki ^c   Bouvet, Michael ^b   Hoffman, Robert M ^a,b  

^a ANTICANCER INC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

1 integrin; antibody therapy; GFP; labeling; lung metastasis; lung seeding; molecular targeted therapy; osteosarcoma cells; real time subcellular in vivo fluorescence imaging; RFP

Indexed keywords

ANTIMETASTATIC AGENT; BETA1 INTEGRIN ANTIBODY; GREEN FLUORESCENT PROTEIN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG METASTASIS; METASTASIS INHIBITION; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MOUSE; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL; PRIMARY TUMOR; PRIORITY JOURNAL; SINGLE CELL ANALYSIS; SURVIVAL TIME; TIBIA; TREATMENT DURATION; TUMOR SEEDING;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD29; CELL LINE, TUMOR; CELL PROLIFERATION; DIAGNOSTIC IMAGING; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM METASTASIS; NEOPLASM SEEDING; OSTEOSARCOMA; SINGLE-CELL ANALYSIS;

EID: 84865546988     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27475     Document Type: Article

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