High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them

Methods

Volumn 57, Issue 2, 2012, Pages 234-248

  Lee, Chrissie Y ^a   Johnson, Ronald L ^b,c   Wichterman Kouznetsova, Jennifer ^b   Guha, Rajarshi ^b   Ferrer, Marc ^b   Tuzmen, Pinar ^b   Martin, Scott E ^b   Zhu, Wenge ^a,d   DePamphilis, Melvin L ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Cancer; DNA re replication; Emi1; Endocycle; Endoreduplication; Fluorescence activated cell sorting; Geminin; High throughput screening; RNAi; SiRNA

Indexed keywords

CELL NUCLEUS DNA; DNA; SMALL INTERFERING RNA;

CANCER CELL; CANCER CHEMOTHERAPY; CELL DIFFERENTIATION; CELL DIVISION; CELL PROLIFERATION; DNA REPLICATION; ENDOREDUPLICATION; GENE DUPLICATION; GENETIC SCREENING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MOLECULAR LIBRARY; POLYPLOIDY; PRIORITY JOURNAL; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DATA INTERPRETATION, STATISTICAL; DNA REPLICATION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84865534585     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2012.03.031     Document Type: Review

References (35)

1. Zhu W., Depamphilis M.L. Cancer Res. 2009, 69:4870-4877.
2. Ullah Z., Lee C.Y., Lilly M.A., DePamphilis M.L. Cell Cycle 2009, 8:1501-1509.
3. Ullah Z., Lee C.Y., Depamphilis M.L. Cell Div. 2009, 4:10.
4. Depamphilis M.L., Bell S.D. Genome Duplication 2010, Garland Science, London. first ed.
5. Sivaprasad U., Dutta A., Bell S.P. Assembly of pre-replication complexes. DNA Replication and Human Disease 2006, 63-88. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. M.L. DePamphilis (Ed.).
6. DePamphilis M.L., Blow J.J., Ghosh S., Saha T., Noguchi K., Vassilev A. Curr. Opin. Cell Biol. 2006.
7. Di Fiore B., Pines J. J. Cell Biol. 2007, 177:425-437.
8. Machida Y.J., Dutta A. Genes Dev. 2007, 21:184-194.
9. Giacomotto J., Segalat L. Br. J. Pharmacol. 2010, 160:204-216.
10. Davidson B.L., McCray P.B. Nat. Rev. Genet. 2011, 12:329-340.
11. Zhu W., Lee C.Y., Johnson R.L., Wichterman J., Huang R., DePamphilis M.L. Mol. Cancer Res. 2011, 9:294-310.
12. Bartz S.R., Zhang Z., Burchard J., Imakura M., Martin M., Palmieri A., Needham R., Guo J., Gordon M., Chung N., Warrener P., Jackson A.L., Carleton M., Oatley M., Locco L., Santini F., Smith T., Kunapuli P., Ferrer M., Strulovici B., Friend S.H., Linsley P.S. Mol. Cell Biol. 2006, 26:9377-9386.
13. Swanton C., Marani M., Pardo O., Warne P.H., Kelly G., Sahai E., Elustondo F., Chang J., Temple J., Ahmed A.A., Brenton J.D., Downward J., Nicke B. Cancer Cell 2007, 11:498-512.
14. Whitehurst A.W., Bodemann B.O., Cardenas J., Ferguson D., Girard L., Peyton M., Minna J.D., Michnoff C., Hao W., Roth M.G., Xie X.J., White M.A. Nature 2007, 446:815-819.
15. Turner N.C., Lord C.J., Iorns E., Brough R., Swift S., Elliott R., Rayter S., Tutt A.N., Ashworth A. EMBO J. 2008, 27:1368-1377.
16. Inglese J., Auld D.S., Jadhav A., Johnson R.L., Simeonov A., Yasgar A., Zheng W., Austin C.P. Proc. Natl Acad. Sci. USA 2006, 103:11473-11478.
17. Birmingham A., Anderson E.M., Reynolds A., Ilsley-Tyree D., Leake D., Fedorov Y., Baskerville S., Maksimova E., Robinson K., Karpilow J., Marshall W.S., Khvorova A. Nat. Methods 2006, 3:199-204.
18. Lin X., Ruan X., Anderson M.G., McDowell J.A., Kroeger P.E., Fesik S.W., Shen Y. Nucleic Acids Res. 2005, 33:4527-4535.
19. Bowen W.P., Wylie P.G. Assay Drug Dev. Technol. 2006, 4:209-221.
20. Soule H.D., Maloney T.M., Wolman S.R., Peterson W.D., Brenz R., McGrath C.M., Russo J., Pauley R.J., Jones R.F., Brooks S.C. Cancer Res. 1990, 50:6075-6086.
21. Zhang J.D., Koerner C., Bechtel S., Bender C., Keklikoglou I., Schmidt C., Irsigler A., Ernst U., Sahin O., Wiemann S., Tschulena U. PLoS ONE 2011, 6:e22176.
22. Kevorkov D., Makarenkov V. J. Biomol. Screen 2005, 10:557-567.
23. Chung N., Zhang X.D., Kreamer A., Locco L., Kuan P.F., Bartz S., Linsley P.S., Ferrer M., Strulovici B. J. Biomol. Screen 2008, 13:149-158.
24. Wang Y., Jadhav A., Southal N., Huang R., Nguyen D.T. Curr. Chem. Genomics 2010, 4:57-66.
25. Blake R.A., Broome M.A., Liu X., Wu J., Gishizky M., Sun L., Courtneidge S.A. Mol. Cell Biol. 2000, 20:9018-9027.
26. Bain J., Plater L., Elliott M., Shpiro N., Hastie C.J., McLauchlan H., Klevernic I., Arthur J.S., Alessi D.R., Cohen P. Biochem. J. 2007, 408:297-315.
27. Brar S.S., Grigg C., Wilson K.S., Holder W.D., Dreau D., Austin C., Foster M., Ghio A.J., Whorton A.R., Stowell G.W., Whittall L.B., Whittle R.R., White D.P., Kennedy T.P. Mol. Cancer Ther. 2004, 3:1049-1060.
28. Alemany R., Olmos G., Garcia-Sevilla J.A. Br. J. Pharmacol. 1995, 114:837-845.
29. Liang Y., Vogel J.L., Narayanan A., Peng H., Kristie T.M. Nat. Med. 2009, 15:1312-1317.
30. Binda C., Valente S., Romanenghi M., Pilotto S., Cirilli R., Karytinos A., Ciossani G., Botrugno O.A., Forneris F., Tardugno M., Edmondson D.E., Minucci S., Mattevi A., Mai A. J. Am. Chem. Soc. 2010, 132:6827-6833.
31. Martin Y.C., Kofron J.L., Traphagen L.M. J. Med. Chem. 2002, 45:4350-4358.
32. Stone D.J., Marine S., Majercak J., Ray W.J., Espeseth A., Simon A., Ferrer M. Cell Cycle 2007, 6:898-901.
33. Malo N., Hanley J.A., Cerquozzi S., Pelletier J., Nadon R. Nat. Biotechnol. 2006, 24:167-175.
34. Consortium G.O. Nucleic Acids Res. 2008, 36:D440-D444.
35. Seethala R., Zhang L. Handbook of Drug Screening 2009, Informa Healthcare, New York. second ed.