Toll-like receptor 9 activation in neutrophils impairs chemotaxis and reduces sepsis outcome

Critical Care Medicine

Volumn 40, Issue 9, 2012, Pages 2631-2637

  Trevelin, Silvia C ^a   Alves Filho, José C ^a   Sônego, Fabiane ^a   Turato, Walter ^a   Nascimento, Daniele C ^a   Souto, Fabricio O ^a   Cunha, Thiago M ^a   Gazzinelli, Ricardo T ^b   Cunha, Fernando Q ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

chemotaxis; CXCR2; failure of neutrophil migration; G protein coupled receptor kinase 2; sepsis; toll like receptor 9

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; G PROTEIN COUPLED RECEPTOR KINASE 2; MYELOPEROXIDASE; TOLL LIKE RECEPTOR 9;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; DOWN REGULATION; FEMALE; INFLAMMATION; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEPSIS; SURVIVAL; WILD TYPE;

ANIMALS; CELL SURVIVAL; CHEMOTAXIS; DISEASE MODELS, ANIMAL; FEMALE; G-PROTEIN-COUPLED RECEPTOR KINASE 2; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; RANDOM ALLOCATION; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SEPSIS; STATISTICS, NONPARAMETRIC; TOLL-LIKE RECEPTOR 9;

EID: 84865524152     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318258fb70     Document Type: Article

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