메뉴 건너뛰기




Volumn 7, Issue 8, 2012, Pages 819-832

Analysis of multiple cell reservoirs expressing unspliced HIV-1 gag-pol mRNA in patients on antiretroviral therapy

Author keywords

activated memory T cell; antiretroviral; cellular reservoirs; HIV 1; macrophage; memory T cell; monocyte; naive T cell; total CD4+; transcriptionally active

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; LAMIVUDINE; MESSENGER RNA;

EID: 84865513216     PISSN: 17460794     EISSN: 17460808     Source Type: Journal    
DOI: 10.2217/fvl.12.69     Document Type: Review
Times cited : (5)

References (70)
  • 1
    • 77954296648 scopus 로고    scopus 로고
    • Good cell, bad cell: Flow cytometry reveals T-cell subsets important in HIV disease
    • Chattopadhyay PK, Roederer M. Good cell, bad cell: Flow cytometry reveals T-cell subsets important in HIV disease. Cytometry A 77, 614-622 (2010).
    • (2010) Cytometry A , vol.77 , pp. 614-622
    • Chattopadhyay, P.K.1    Roederer, M.2
  • 2
    • 53849134844 scopus 로고    scopus 로고
    • Cellular reservoirs of HIV-1 and their role in viral persistence
    • Alexaki A, Liu Y, Wigdahl B. Cellular reservoirs of HIV-1 and their role in viral persistence. Curr. HIV Res. 6, 388-400 (2008).
    • (2008) Curr. HIV Res. , vol.6 , pp. 388-400
    • Alexaki, A.1    Liu, Y.2    Wigdahl, B.3
  • 3
    • 79957966626 scopus 로고    scopus 로고
    • Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy
    • Chun TW, Murray D, Justement JS et al. Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy. J. Infect. Dis. 204(1), 135-138 (2011).
    • (2011) J. Infect. Dis. , vol.204 , Issue.1 , pp. 135-138
    • Chun, T.W.1    Murray, D.2    Justement, J.S.3
  • 4
    • 79952204267 scopus 로고    scopus 로고
    • Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure
    • Sharkey M, Babic DZ, Greenough T, Gulick R, Kuritzkes DR, Stevenson M. Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure. Plos Pathog. 7(2), E1001303 (2011).
    • (2011) Plos Pathog , vol.7 , Issue.2
    • Sharkey, M.1    Babic, D.Z.2    Greenough, T.3    Gulick, R.4    Kuritzkes, D.R.5    Stevenson, M.6
  • 6
    • 79955777644 scopus 로고    scopus 로고
    • Evaluation of the Roche COBAS® TaqMan® HIV-1 test for quantifying HIV-1 RNA in infected cells and lymphoid tissue
    • Gil C, Garcia MT, Garcia F et al. Evaluation of the Roche COBAS® TaqMan® HIV-1 test for quantifying HIV-1 RNA in infected cells and lymphoid tissue. J. Virol. Methods 174, 69-76 (2011).
    • (2011) J. Virol. Methods , vol.174 , pp. 69-76
    • Gil, C.1    Garcia, M.T.2    Garcia, F.3
  • 7
    • 79551712331 scopus 로고    scopus 로고
    • Cell-associated viral burden provides evidence of ongoing viral replication in aviremic HIV-2-infected patients
    • Soares RS, Tendeiro R, Foxall RB et al. Cell-associated viral burden provides evidence of ongoing viral replication in aviremic HIV-2-infected patients. J. Virol. 85, 2429-2438 (2011).
    • (2011) J. Virol. , vol.85 , pp. 2429-2438
    • Soares, R.S.1    Tendeiro, R.2    Foxall, R.B.3
  • 8
    • 77949530887 scopus 로고    scopus 로고
    • Cellular levels of HIV unspliced RNA from patients on combination antiretroviral therapy with undetectable plasma viremia predict the therapy outcome
    • Pasternak AO, Jurriaans S, Bakker M, Prins JM, Berkhout B, Lukashov VV. Cellular levels of HIV unspliced RNA from patients on combination antiretroviral therapy with undetectable plasma viremia predict the therapy outcome. Plos One 4, E8490 (2009).
    • (2009) Plos One , vol.4
    • Pasternak, A.O.1    Jurriaans, S.2    Bakker, M.3    Prins, J.M.4    Berkhout, B.5    Lukashov, V.V.6
  • 12
    • 63449124466 scopus 로고    scopus 로고
    • Emerging concepts in the immunopathogenesis of AIDS
    • Douek DC, Roederer M, Koup RA. Emerging concepts in the immunopathogenesis of AIDS. Annu. Rev. Med. 60, 471-484 (2009).
    • (2009) Annu. Rev. Med. , vol.60 , pp. 471-484
    • Douek, D.C.1    Roederer, M.2    Koup, R.A.3
  • 13
    • 74549154662 scopus 로고    scopus 로고
    • Immune activation and the pathogenesis of HIV disease: Implications for therapy
    • Fernandez S, Lim A, French M. Immune activation and the pathogenesis of HIV disease: Implications for therapy. J. HIV Ther. 14, 52-56 (2009).
    • (2009) J. HIV Ther. , vol.14 , pp. 52-56
    • Fernandez, S.1    Lim, A.2    French, M.3
  • 14
    • 74549115403 scopus 로고    scopus 로고
    • HIV as an inflammatory disease
    • Smith D. HIV as an inflammatory disease. J. HIV Ther. 14, 50-51 (2009).
    • (2009) J. HIV Ther. , vol.14 , pp. 50-51
    • Smith, D.1
  • 15
    • 73449117263 scopus 로고    scopus 로고
    • Modeling latently infected cell activation: Viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
    • Rong L, Perelson AS. Modeling latently infected cell activation: Viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy. Plos Comput. Biol. 5, 1-18 (2009).
    • (2009) Plos Comput. Biol. , vol.5 , pp. 1-18
    • Rong, L.1    Perelson, A.S.2
  • 16
    • 39849096860 scopus 로고    scopus 로고
    • Immune activation and AIDS pathogenesis
    • DOI 10.1097/QAD.0b013e3282f2dbe7, PII 0000203020080219000001
    • Sodora DL, Silvestri G. Immune activation and AIDS pathogenesis. AIDS 22, 439-446 (2008). (Pubitemid 351317285)
    • (2008) AIDS , vol.22 , Issue.4 , pp. 439-446
    • Sodora, D.L.1    Silvestri, G.2
  • 17
    • 34548088101 scopus 로고    scopus 로고
    • Transient viremia, plasma viral load, and reservoir replenishment in HIV-infected patients on antiretroviral therapy
    • DOI 10.1097/QAI.0b013e3180654836, PII 0012633420070815000001
    • Jones LE, Perelson AS. Transient viremia, plasma viral load, and reservoir replenishment in HIV-infected patients on antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 15, 483-493 (2007). (Pubitemid 47294919)
    • (2007) Journal of Acquired Immune Deficiency Syndromes , vol.45 , Issue.5 , pp. 483-493
    • Jones, L.E.1    Perelson, A.S.2
  • 19
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin JM. HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy. Science 267, 483-489 (1995).
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 20
    • 79952110521 scopus 로고    scopus 로고
    • Simultaneous ultrasensitive subpopulation staining/hybridization in situ (SUSHI) in HIV-1 disease monitoring
    • Patterson BK. Simultaneous ultrasensitive subpopulation staining/hybridization in situ (SUSHI) in HIV-1 disease monitoring. Methods Mol. Biol. 659, 337-346 (2010).
    • (2010) Methods Mol. Biol. , vol.659 , pp. 337-346
    • Patterson, B.K.1
  • 21
    • 0035822946 scopus 로고    scopus 로고
    • Persistence of intracellular HIV-1 mRNA correlates with HIV-1-specific immune responses in infected subjects on stable HAART
    • DOI 10.1097/00002030-200109070-00005
    • Patterson BK, McCallister S, Schutz M et al. Persistence of intracellular HIV-1 mRNA correlates with HIV-1-specific immune responses in infected subjects on stable HAART. AIDS 15, 1635-1641 (2001). (Pubitemid 32923062)
    • (2001) AIDS , vol.15 , Issue.13 , pp. 1635-1641
    • Patterson, B.K.1    McCallister, S.2    Schutz, M.3    Siegel, J.N.4    Shults, K.5    Flener, Z.6    Landay, A.7
  • 22
    • 0033385794 scopus 로고    scopus 로고
    • Cell-associated HIV-1 messenger RNA and DNA in T-helper cell and monocytes in asymptomatic HIV-1-infected subjects on HAART plus an inactivated HIV-1 immunogen
    • DOI 10.1097/00002030-199909100-00002
    • Patterson BK, Carlo DJ, Kaplan MH, Marecki M, Pawha S. Cell-associated HIV-1 messenger RNA and DNA in T-helper cell and monocytes in asymptomatic HIV-1-infected subjects on HAART plus an inactivated HIV-1 immunogen. AIDS 13(13), 1607-1611 (1999). (Pubitemid 30015706)
    • (1999) AIDS , vol.13 , Issue.13 , pp. 1607-1611
    • Patterson, B.K.1    Carlo, D.J.2    Kaplan, M.H.3    Marecki, M.4    Pawha, S.5    Moss, R.B.6
  • 23
    • 0031956807 scopus 로고    scopus 로고
    • Detection of HIV-RNA-positive monocytes in peripheral blood of HIV- positive patients by simultaneous flow cytometric analysis of intracellular HIV RNA and cellular immunophenotype
    • DOI 10.1002/(SICI)1097-0320(19980401)31:4 <265::AID-CYTO6>3.0.CO;2- I
    • Patterson BK, Mosiman VL, Cantarero L, Furtado M, Bhattacharya M, Goolsby C. Detection of HIV-RNA-positive monocytes in peripheral blood of HIV-positive patients by simultaneous flow cytometric analysis of intracellular HIV RNA and cellular immunophenotype. Cytometry 31, 265-274 (1998). (Pubitemid 28162978)
    • (1998) Cytometry , vol.31 , Issue.4 , pp. 265-274
    • Patterson, B.K.1    Mosiman, V.L.2    Cantarero, L.3    Furtado, M.4    Bhattacharya, M.5    Goolsby, C.6
  • 24
    • 70349436101 scopus 로고    scopus 로고
    • Determination of hepatitis C virus-infected, monocyte lineage reservoirs in individuals with or without HIV coinfection
    • Coquillard G, Patterson BK. Determination of hepatitis C virus-infected, monocyte lineage reservoirs in individuals with or without HIV coinfection. J. Infect. Dis. 200, 947-954 (2009).
    • (2009) J. Infect. Dis. , vol.200 , pp. 947-954
    • Coquillard, G.1    Patterson, B.K.2
  • 26
    • 0033634864 scopus 로고    scopus 로고
    • Up-regulation of CCR5 expression in the placenta is associated with human immunodeficiency virus-1 vertical transmission
    • Behbahani H, Popek E, Garcia P et al. Up-regulation of CCR5 expression in the placenta is associated with human immunodeficiency virus-1 vertical transmission. Am. J. Pathol. 157, 1811-1818 (2000).
    • (2000) Am. J. Pathol. , vol.157 , pp. 1811-1818
    • Behbahani, H.1    Popek, E.2    Garcia, P.3
  • 28
    • 0034033172 scopus 로고    scopus 로고
    • Development of an in vitro organ culture model to study transmission of HIV-1 in the female genital tract
    • DOI 10.1038/74743
    • Collins KB, Patterson BK, Naus GJ, Landers DV, Gupta P. Development of an in vitro organ culture model to study transmission of HIV-1 in the female genital tract. Nat. Med. 6, 475-479 (2000). (Pubitemid 30208169)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 475-479
    • Collins, K.B.1    Patterson, B.K.2    Naus, G.J.3    Landers, D.V.4    Gupta, P.5
  • 29
    • 61849179239 scopus 로고    scopus 로고
    • A Phase I study to explore the activity and safety of SCH532706, a small molecule chemokine receptor-5 antagonist in HIV type-1-infected patients
    • Pett SL, McCarthy MC, Cooper DA et al. A Phase I study to explore the activity and safety of SCH532706, a small molecule chemokine receptor-5 antagonist in HIV type-1-infected patients. Antivir. Ther. 14, 111-115 (2009).
    • (2009) Antivir. Ther. , vol.14 , pp. 111-115
    • Pett, S.L.1    McCarthy, M.C.2    Cooper, D.A.3
  • 30
    • 0033016482 scopus 로고    scopus 로고
    • Monitoring HIV-1 treatment in immune-cell subsets with ultrasensitive fluorescence-in-situ hybridisation
    • DOI 10.1016/S0140-6736(05)77222-6
    • Patterson BK, Czerniewski MA, Pottage J, Agnoli M, Kessler H, Landay A. Monitoring HIV-1 treatment in immune-cell subsets with ultrasensitive fluorescence-in-situ hybridisation. Lancet 353(9148), 211-212 (1999). (Pubitemid 29088043)
    • (1999) Lancet , vol.353 , Issue.9148 , pp. 211-212
    • Patterson, B.K.1    Czerniewski, M.A.2    Pottage, J.3    Agnoli, M.4    Kessler, H.5    Landay, A.6
  • 31
    • 0010472999 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone
    • Folks TM, Clouse KA, Justement J et al. Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc. Natl Acad. Sci. USA 86(7), 2365-2368 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.86 , Issue.7 , pp. 2365-2368
    • Folks, T.M.1    Clouse, K.A.2    Justement, J.3
  • 32
    • 0023508507 scopus 로고
    • Cytokine induced expression of HIV-1 in a chronically-infected promonocyte cell line
    • Folks TM, Justement J, Kinter A, Dinarello CA, Fauci AS. Cytokine induced expression of HIV-1 in a chronically-infected promonocyte cell line. Science 238, 800-802 (1987).
    • (1987) Science , vol.238 , pp. 800-802
    • Folks, T.M.1    Justement, J.2    Kinter, A.3    Dinarello, C.A.4    Fauci, A.S.5
  • 33
    • 53049084290 scopus 로고    scopus 로고
    • HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells
    • Rosenstiel PE, Gruosso T, Letourneau AM et al. HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. Kidney Int. 74(8), 1049-1058 (2008).
    • (2008) Kidney Int , vol.74 , Issue.8 , pp. 1049-1058
    • Rosenstiel, P.E.1    Gruosso, T.2    Letourneau, A.M.3
  • 34
    • 0028217413 scopus 로고
    • Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus
    • Pearce-Pratt R, Malamud D, Phillips DM. Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus. J. Virol. 68(5), 2898-2905 (1994). (Pubitemid 24129737)
    • (1994) Journal of Virology , vol.68 , Issue.5 , pp. 2898-2905
    • Pearce-Pratt, R.1    Malamud, D.2    Phillips, D.M.3
  • 36
    • 0027410459 scopus 로고
    • Induction of cell differentiation by human immunodeficiency virus 1 vpr
    • DOI 10.1016/0092-8674(93)90073-Y
    • Levy DN, Fernandes LS, Williams WV, Weiner DB. Induction of cell differentiation by human immunodeficiency virus 1 vpr. Cell 72(4), 541-550 (1993). (Pubitemid 23077742)
    • (1993) Cell , vol.72 , Issue.4 , pp. 541-550
    • Levy, D.N.1    Fernandes, L.S.2    Williams, W.V.3    Weiner, D.B.4
  • 37
    • 0027064712 scopus 로고
    • Membrane alterations linked to early interactions of HIV with the cell surface
    • DOI 10.1016/0042-6822(92)90269-U
    • Fermin CD, Garry RF. Membrane alterations linked to early interactions of HIV with the cell surface. Virology 191(2), 941-946 (1992). (Pubitemid 23022498)
    • (1992) Virology , vol.191 , Issue.2 , pp. 941-946
    • Fermin, C.D.1    Garry, R.F.2
  • 38
    • 33748626539 scopus 로고    scopus 로고
    • Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission
    • Groot F, van Capel TM, Schuitemaker J, Berkhout B, de Jong EC. Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission. Retrovirology 3, 1-10 (2006).
    • (2006) Retrovirology , vol.3 , pp. 1-10
    • Groot, F.1    Van Capel, T.M.2    Schuitemaker, J.3    Berkhout, B.4    De Jong, E.C.5
  • 39
    • 0026055182 scopus 로고
    • Human immunodeficiency virus DNA is present in a high percentage of CD4+ lymphocytes of seropositive individuals
    • Hsia K, Spector SA. Human immunodeficiency virus DNA is present in a high percentage of CD4+ lymphocytes of seropositive individuals. J. Infect. Dis. 164, 470-475 (1991).
    • (1991) J. Infect. Dis. , vol.164 , pp. 470-475
    • Hsia, K.1    Spector, S.A.2
  • 41
    • 13444309162 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1128/JVI.79.4.2199-2210.2005
    • Zhou Y, Zhang H, Siliciano JD, Siliciano RF. Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells. J. Virol. 79, 2199-2210 (2005). (Pubitemid 40204577)
    • (2005) Journal of Virology , vol.79 , Issue.4 , pp. 2199-2210
    • Zhou, Y.1    Zhang, H.2    Siliciano, J.D.3    Siliciano, R.F.4
  • 42
    • 3242723423 scopus 로고    scopus 로고
    • HIV infection of primary human T cells is determined by tunable thresholds of T cell activation
    • DOI 10.1002/eji.200424892
    • Oswald-Richter K, Grill SM, Leelawong M, Unutmaz D. HIV infection of primary human T cells is determined by tunable thresholds of T cell activation. Eur. J. Immunol. 34, 1705-1714 (2004). (Pubitemid 39256053)
    • (2004) European Journal of Immunology , vol.34 , Issue.6 , pp. 1705-1714
    • Oswald-Richter, K.1    Grill, S.M.2    Leelawong, M.3    Unutmaz, D.4
  • 43
    • 0033532628 scopus 로고    scopus 로고
    • Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes
    • DOI 10.1084/jem.189.11.1735
    • Unutmaz D, KewalRamani VN, Marmon S, Littman DR. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes. J. Exp. Med. 189, 1735-1746 (1999). (Pubitemid 29272690)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.11 , pp. 1735-1746
    • Unutmaz, D.1    KewalRamani, V.N.2    Marmon, S.3    Littman, D.R.4
  • 44
    • 0038342442 scopus 로고    scopus 로고
    • HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
    • DOI 10.1038/nature01749
    • Swingler S, Brichacek B, Jacque JM, Ulich C, Zhou J, Stevenson M. HIV-1 Nef intersects the macrophage CD40L signaling pathway to promote resting-cell infection. Nature 424, 213-219 (2003). (Pubitemid 36858691)
    • (2003) Nature , vol.424 , Issue.6945 , pp. 213-219
    • Swingler, S.1    Brichacek, B.2    Jacque, J.-M.3    Ulich, C.4    Zhou, J.5    Stevenson, M.6
  • 45
    • 0242364699 scopus 로고    scopus 로고
    • + t cells: Role of lymphoid tissue microenvironment and effect of immunomodulating agents
    • DOI 10.1089/088922203322493012
    • Kinter A, Moorthy A, Jackson R, Fauci AS. Productive HIV infection of resting CD4+ T cells: Role of lymphoid tissue microenvironment and effect of immunomodulating agents. AIDS Res. Hum. Retroviruses 19, 847-856 (2003). (Pubitemid 37338910)
    • (2003) AIDS Research and Human Retroviruses , vol.19 , Issue.10 , pp. 847-856
    • Kinter, A.1    Moorthy, A.2    Jackson, R.3    Fauci, A.S.4
  • 47
    • 0032742547 scopus 로고    scopus 로고
    • Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells
    • Zhang Z, Schuler T, Zupancic M et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science 286, 1353-1357 (1999).
    • (1999) Science , vol.286 , pp. 1353-1357
    • Zhang, Z.1    Schuler, T.2    Zupancic, M.3
  • 48
    • 0037302334 scopus 로고    scopus 로고
    • Latency in human immunodeficiency virus type 1 infection: No easy answers
    • DOI 10.1128/JVI.77.3.1659-1665.2003
    • Persaud D, Zhou Y, Siliciano JM, Siliciano RF. Latency in human immunodeficiency virus type 1 infection: No easy answers. J. Virol. 77, 1659-1665 (2003). (Pubitemid 36109978)
    • (2003) Journal of Virology , vol.77 , Issue.3 , pp. 1659-1665
    • Persaud, D.1    Zhou, Y.2    Siliciano, J.M.3    Siliciano, R.F.4
  • 51
    • 0036138852 scopus 로고    scopus 로고
    • + monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy
    • DOI 10.1128/JVI.76.2.707-716.2002
    • Zhu T, Muthui D, Holte S et al. Evidence for human immunodeficiency virus type 1 replication in vivo in CD14+ monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy. J. Virol. 76, 707-716 (2002). (Pubitemid 34033369)
    • (2002) Journal of Virology , vol.76 , Issue.2 , pp. 707-716
    • Zhu, T.1    Muthui, D.2    Holte, S.3    Nickle, D.4    Feng, F.5    Brodie, S.6    Hwangbo, Y.7    Mullins, J.I.8    Corey, L.9
  • 53
    • 0037045054 scopus 로고    scopus 로고
    • Persistence of replication-competent HIV in both memory and naive CD4 T cell subsets in patients on prolonged and effective HAART
    • DOI 10.1097/00002030-200211080-00007
    • Lambotte O, Demoustier A, de Goër MG et al. Persistence of replication-competent HIV in both memory and naive CD4 T cell subsets in patients on prolonged and effective HAART. AIDS 16, 2151-2157 (2002). (Pubitemid 35387269)
    • (2002) AIDS , vol.16 , Issue.16 , pp. 2151-2157
    • Lambotte, O.1    Demoustier, A.2    De Goer, M.G.3    Wallon, C.4    Gasnault, J.5    Goujard, C.6    Delfraissy, J.F.7    Taoufik, Y.8
  • 54
    • 0030968495 scopus 로고    scopus 로고
    • Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro
    • Spina CA, Prince HE, Richman DD. Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro. J. Clin. Invest. 99, 1774-1785 (1997). (Pubitemid 27163830)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.7 , pp. 1774-1785
    • Spina, C.A.1    Prince, H.E.2    Richman, D.D.3
  • 55
    • 0031016699 scopus 로고    scopus 로고
    • Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells
    • Woods TC, Roberts BD, Butera ST, Folks TM. Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells. Blood 89, 1635-1641 (1997). (Pubitemid 27097457)
    • (1997) Blood , vol.89 , Issue.5 , pp. 1635-1641
    • Woods, T.C.1    Roberts, B.D.2    Butera, S.T.3    Folks, T.M.4
  • 56
    • 0037189506 scopus 로고    scopus 로고
    • Nuclear factor of activated T cells is a driving force for preferential productive HIV-1 infection of CD45RO-expressing CD4+ T cells
    • DOI 10.1074/jbc.M201563200
    • Robichaud GA, Barbeau B, Fortin JF, Rothstein DM, Tremblay MJ. Nuclear factor of activated T cells is a driving force for preferential productive HIV-1 infection of CD45RO-expressing CD4+ T cells. J. Biol. Chem. 277, 23733-23741 (2002). (Pubitemid 34952214)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.26 , pp. 23733-23741
    • Robichaud, G.A.1    Barbeau, B.2    Fortin, J.-F.3    Rothstein, D.M.4    Tremblay, M.J.5
  • 58
    • 77950676781 scopus 로고    scopus 로고
    • Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage
    • Le Douce V, Herbein G, Rohr O, Schwartz C. Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage. Retrovirology 7, 1-16 (2010).
    • (2010) Retrovirology , vol.7 , pp. 1-16
    • Le Douce, V.1    Herbein, G.2    Rohr, O.3    Schwartz, C.4
  • 59
    • 72249123176 scopus 로고    scopus 로고
    • Intracellular pharmacokinetics of antiretroviral drugs in HIV-infected patients, and their correlation with drug action
    • Bazzoli C, Jullien V, Le Tiec C, Rey E, Mentré F, Taburet AM. Intracellular pharmacokinetics of antiretroviral drugs in HIV-infected patients, and their correlation with drug action. Clin. Pharmacokinet. 49, 17-45 (2010).
    • (2010) Clin. Pharmacokinet. , vol.49 , pp. 17-45
    • Bazzoli, C.1    Jullien, V.2    Le Tiec, C.3    Rey, E.4    Mentré, F.5    Taburet, A.M.6
  • 60
    • 76449103996 scopus 로고    scopus 로고
    • Identification of a potential pharmacological sanctuary for HIV type 1 in a fraction of CD4+ primary cells
    • Valentin A, Morrow M, Poirier RH et al. Identification of a potential pharmacological sanctuary for HIV type 1 in a fraction of CD4+ primary cells. AIDS Res. Hum. Retroviruses 26, 79-88 (2010).
    • (2010) AIDS Res. Hum. Retroviruses , vol.26 , pp. 79-88
    • Valentin, A.1    Morrow, M.2    Poirier, R.H.3
  • 61
    • 66749103433 scopus 로고    scopus 로고
    • The transport of anti-HIV drugs across blood-CNS interfaces: Summary of current knowledge and recommendations for further research
    • Varatharajan L, Thomas SA. The transport of anti-HIV drugs across blood-CNS interfaces: Summary of current knowledge and recommendations for further research. Antivir. Res. 82, 99-109 (2009).
    • (2009) Antivir. Res. , vol.82 , pp. 99-109
    • Varatharajan, L.1    Thomas, S.A.2
  • 64
    • 77957063611 scopus 로고    scopus 로고
    • Resistant viral variants in cellular reservoirs of human immunodeficiency virus infection
    • Turriziani O, Andreoni M, Antonelli G. Resistant viral variants in cellular reservoirs of human immunodeficiency virus infection. Clin. Microbiol. Infect. 16, 1518-1524 (2010).
    • (2010) Clin. Microbiol. Infect. , vol.16 , pp. 1518-1524
    • Turriziani, O.1    Andreoni, M.2    Antonelli, G.3
  • 65
    • 77954209627 scopus 로고    scopus 로고
    • Mutational resistance pattern of HIV type 1 in CD14+ monocytes, CD4+ T cells, and plasma from treated patients
    • Turriziani O, Boni A, Falasca F et al. Mutational resistance pattern of HIV type 1 in CD14+ monocytes, CD4+ T cells, and plasma from treated patients. AIDS Res. Hum. Retroviruses 26, 625-634 (2010).
    • (2010) AIDS Res. Hum. Retroviruses , vol.26 , pp. 625-634
    • Turriziani, O.1    Boni, A.2    Falasca, F.3
  • 68
    • 0037455578 scopus 로고    scopus 로고
    • Differential cellular distribution of HIV-1 drug resistance in vivo: Evidence for infection of CD8+ T cells during HAART
    • DOI 10.1006/viro.2002.1703
    • Potter SJ, Dwyer DE, Saksena NK. Differential cellular distribution of HIV-1 drug resistance in vivo: Evidence for infection of CD8+ T cells during HAART. Virology 305, 339-352 (2003). (Pubitemid 36259668)
    • (2003) Virology , vol.305 , Issue.2 , pp. 339-352
    • Potter, S.J.1    Dwyer, D.E.2    Saksena, N.K.3
  • 69
    • 59349092367 scopus 로고    scopus 로고
    • Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy
    • Fischer M, Joos B, Niederöst B et al. Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy. Retrovirology 5, 107 (2008).
    • (2008) Retrovirology , vol.5 , pp. 107
    • Fischer, M.1    Joos, B.2    Niederöst, B.3
  • 70
    • 77952540443 scopus 로고    scopus 로고
    • Pathogenesis of HIV infection: Total CD4+ T-cell pool, immune activation, and inflammation
    • Lane HC. Pathogenesis of HIV infection: Total CD4+ T-cell pool, immune activation, and inflammation. Top. HIV Med. 18, 2-6 (2010).
    • (2010) Top. HIV Med. , vol.18 , pp. 2-6
    • Lane, H.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.