Second-generation arthroscopic autologous chondrocyte implantation for the treatment of degenerative cartilage lesions

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 20, Issue 9, 2012, Pages 1704-1713

  Filardo, Giuseppe ^a   Kon, Elizaveta ^a   Martino, Alessandro Di ^a   Patella, Silvio ^a   Altadonna, Giulio ^a   Balboni, Federica ^a   Bragonzoni, Laura ^a   Visani, Andrea ^a   Marcacci, Maurilio ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

Arthroscopy; Cartilage degeneration; Knee; Second generation autologous chondrocyte implantation

Indexed keywords

HYALURONIC ACID; IMMUNOLOGICAL ADJUVANT; TISSUE SCAFFOLD;

ADULT; ARTHROSCOPY; ARTICLE; ARTICULAR CARTILAGE; AUTOTRANSPLANTATION; CARTILAGE CELL; CHONDROPATHY; FEMALE; HUMAN; KNEE; MALE; TRANSPLANTATION;

ADJUVANTS, IMMUNOLOGIC; ADULT; ARTHROSCOPY; CARTILAGE DISEASES; CARTILAGE, ARTICULAR; CHONDROCYTES; FEMALE; HUMANS; HYALURONIC ACID; KNEE JOINT; MALE; TISSUE SCAFFOLDS; TRANSPLANTATION, AUTOLOGOUS; YOUNG ADULT;

EID: 84865504010     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-011-1732-5     Document Type: Article

References (51)

1. Bae DK, Yoon KH, Song SJ (2006) Cartilage healing after microfracture in osteoarthritic knees. Arthroscopy 22(4): 367-374.
2. Basad E, Ishaque B, Bachmann G, Stürz H, Steinmeyer J (2010) Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study. Knee Surg Sports Traumatol Arthrosc 18(4): 519-527.
3. Behrens P, Bitter T, Kurz B, Russlies M (2006) Matrix-associated autologous chondrocyte transplantation/implantation (MATC/MACI) 5 year follow-up. Knee 13: 194-202.
4. Bekkers JE, Inklaar M, Saris DB (2009) Treatment selection in articular cartilage lesions of the knee: a systematic review. Am J Sports Med 37(1): 148S-155S.
5. Bosnakovski D, Mizuno M, Kim G, Takagi S, Okumura M, Fujinaga T (2006) Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells (MSCs) in different hydrogels: influence of collagen type II extracellular matrix on MSC chondrogenesis. Biotechnol Bioeng 20 93(6): 1152-1163.
6. Brittberg M (2010) Cell carriers as the next generation of cell therapy for cartilage repair: a review of the matrix-induced autologous chondrocyte implantation procedure. Am J Sports Med 38(6): 1259-1271.
7. Brittberg M, Lindahl A, Ohlsson C, Isaksson O, Peterson L (1994) Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331: 889-895.
8. Browne JE, Anderson AF, Arciero R et al (2005) Clinical outcome of autologous chondrocyte implantation at 5 years in US subjects. Clin Orthop Relat Res 436: 237-245.
9. Buckwalter JA, Mankin HJ (1997) Articular cartilage. J Bone Joint Surg 79A(4): 600-611.
10. Buckwalter JA, Mankin HJ (1997) Articular cartilage. Part II: degeneration and osteoarthrosis, repair, regeneration, and transplantation. J Bone Joint Surg 79A(4): 612-632.
11. Cavallo C, Desando G, Facchini A, Grigolo B (2010) Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold. J Biomed Mater Res A 93(1): 86-95.
12. Cicuttini F, Ding C, Wluka A, Davis S, Ebeling PR, Jones G (2005) Association of cartilage defects with loss of knee cartilage in healthy, middle-age adults: a prospective study. Arthritis Rheum 52(7): 2033-2039.
13. Davies-Tuck ML, Wluka AE, Wang Y, Teichtahl AJ, Jones G, Ding C, Cicuttini FM (2008) The natural history of cartilage defects in people with knee osteoarthritis. Osteoarthr Cartil 16(3): 337-342.
14. de Windt TS, Bekkers JE, Creemers LB, Dhert WJ, Saris DB (2009) Patient profiling in cartilage regeneration: prognostic factors determining success of treatment for cartilage defects. Am J Sports Med 37(1): 58S-62S.
15. Della Villa S, Kon E, Filardo G, Ricci M, Vincentelli F, Delcogliano M, Marcacci M (2010) Does intensive rehabilitation permit early return to sport without compromising the clinical outcome after arthroscopic autologous chondrocyte implantation in highly competitive athletes? Am J Sports Med 38(1): 68-77.
16. Ferruzzi A, Buda R, Faldini C, Vannini F et al (2008) Autologous chondrocyte implantation in the knee joint: open compared with arthroscopic technique. Comparison at a minimum follow-up of 5 years. J Bone Joint Surg Am 90(4): 90-101.
17. Filardo G, Kon E, Berruto M, et al. (2011) Arthroscopic second generation autologous chondrocytes implantation associated to bone grafting for the treatment of knee osteochondritis dissecans: results at 6 years. The Knee. doi: 10. 1016/j. knee. 2011. 08. 007.
18. Filardo G, Kon E, Di Martino A, Iacono F, Marcacci M (2011) Arthroscopic second-generation autologous chondrocyte implantation: A prospective 7-year follow-up study. Am J Sports Med. doi: 10. 1177/0363546511415658.
19. Gille J, Schuseil E, Wimmer J, Gellissen J, Schulz AP, Behrens P (2010) Mid-term results of autologous matrix-induced chondrogenesis for treatment of focal cartilage defects in the knee. Knee Surg Sports Traumatol Arthrosc 18(11): 1456-1464.
20. Gobbi A, Kon E, Berruto M et al (2009) Patellofemoral full-thickness chondral defects treated with second-generation autologous chondrocyte implantation: results at 5 years' follow-up. Am J Sports Med 37(6): 1083-1092.
21. Gomoll AH, Madry H, Knutsen G, van Dijk N, Seil R, Brittberg M, Kon E (2010) The subchondral bone in articular cartilage repair: current problems in the surgical management. Knee Surg Sports Traumatol Arthrosc 18(4): 434-447.
22. Gratz KR, Wong BL, Bae WC, Sah RL (2009) The effects of focal articular defects on cartilage contact mechanics. J Orthop Res 27(5): 584-592.
23. Hollander AP, Dickinson SC, Sims TJ et al (2006) Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees. Tissue Eng 12(7): 1787-1798.
24. ICRS Cartilage Injury Evaluation Package 2000 http://www.cartilage.org/Evaluation_Package/ICRS_Evaluation.pdf.
25. Knutsen G, Engebretsen L, Ludvigsen TC et al (2004) Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial. J Bone Joint Surg Am 86(3): 455-464.
26. Knutsen G, Drogset JO, Engebretsen L et al (2007) A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at 5 years. J Bone Joint Surg Am 89(10): 2105-2112.
27. Kon E, Delcogliano M, Filardo G, Montaperto C, Marcacci M (2008) Second generation issues in cartilage repair. Sports Med Arthrosc 16(4): 221-229.
28. Kon E, Filardo G, Berruto M, Benazzo F, Zanon G, Della Villa S, Marcacci M (2011) Articular cartilage treatment in high-level male soccer players: a prospective comparative study of arthroscopic second-generation autologous chondrocyte implantation versus microfracture. Am J Sports Med. doi: 10. 1177/0363546511420688.
29. Kon E, Gobbi A, Filardo G, Delcogliano M, Zaffagnini S, Marcacci M (2009) Arthroscopic second-generation autologous chondrocyte implantation compared with microfracture for chondral lesions of the knee: prospective nonrandomized study at 5 years. Am J Sports Med 37(1): 33-41.
30. Kon E, Verdonk P, Condello V et al (2009) Matrix-assisted autologous chondrocyte transplantation for the repair of cartilage defects of the knee: systematic clinical data review and study quality analysis. Am J Sports Med 37(1): 156S-166S.
31. Kreuz PC, Müller S, Ossendorf C, Kaps C, Erggelet C (2009) Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four-year clinical results. Arthritis Res Ther 11(2): R33.
32. Løken S, Ludvigsen TC, Høysveen T, Holm I, Engebretsen L, Reinholt FP (2009) Autologous chondrocyte implantation to repair knee cartilage injury: ultrastructural evaluation at 2 years and long-term follow-up including muscle strength measurements. Knee Surg Sports Traumatol Arthrosc 17(11): 1278-1288.
33. Marcacci M, Zaffagnini S, Kon E, Visani A, Iacono F, Loreti I (2002) Arthroscopic autologous chondrocyte transplantation: technical note. Knee Surg Sports Traumatol Arthrosc 10(3): 154-159.
34. Marlovits S, Singer P, Zeller P et al (2006) Magnetic resonance observation of cartilage repair tissue (MOCART) for the evaluation of autologous chondrocyte transplantation: determination of interobserver variability and correlation to clinical outcome after 2 years. Eur J Radiol 57(1): 16-23.
35. Miller BS, Steadman JR, Briggs KK, Rodrigo JJ, Rodkey WG (2004) Patient satisfaction and outcome after microfracture of the degenerative knee. J Knee Surg 17(1): 13-17.
36. Minas T, Gomoll AH, Solpour S, Rosenberger R, Probst C, Bryant T (2010) Autologous chondrocyte transplantation for joint preservation in patients with early osteoarthritis. Clin Orthop Relat Res 468: 146-157.
37. Mithöfer K, Minas T, Peterson L, Yeon H, Micheli LJ (2005) Functional outcome of articular cartilage repair in adolescent athletes. Am J Sports Med 33: 1147-1153.
38. Mithoefer K, Williams RJ, Warren RF, Wickiewicz TL, Marx RG (2006) High-impact athletics after knee articular cartilage repair: A prospective evaluation of the microfracture technique. Am J Sports Med 34: 1413-1418.
39. Nehrer S, Domayer S, Dorotka S, et al. (2007) Five years clinical results after matrix assisted autologous chondrocyte transplantation using a hyaluronan matrix. Osteoarthr Cartil. 15(B, 16. 7): 74.
40. Ochi M, Uchio Y, Kawasaki K, Wakitani S, Iwasa J (2002) Transplantation of cartilage-like tissue made by tissue engineering in the treatment of cartilage defects of the knee. J Bone Joint Surg Br 84(4): 571-578.
41. Ossendorf C, Kaps C, Kreuz PC, Burmester GR, Sittinger M, Erggelet C (2007) Treatment of posttraumatic and focal osteoarthritic cartilage defects of the knee with autologous polymer-based three-dimensional chondrocyte grafts: 2-year clinical results. Arthritis Res Ther 9(2): R41.
42. Ozsoy MH, Aydogdu S, Taskiran D, Sezak M, Hayran M, Oztop F, Ozsoy A (2009) The effects of early or late treatment of osteochondral defects on joint homoeostasis: an experimental study in rabbits. Knee Surg Sports Traumatol Arthrosc 17(6): 578-589.
43. Peterson L, Brittberg M, Kiviranta I, Akerlund EL, Lindahl A (2002) Autologous chondrocyte transplantation. Biomechanics and long-term durability. Am J. Sports Med 30(1): 2-12.
44. Rodrigo JJ, Steadman JR, Syftestad G, Benton H, Silliman J (1995) Effects of human knee synovial fluid on chondrogenesis in vitro. Am J Knee Surg 8(4): 124-129.
45. Saris DB, Dhert WJ, Verbout AJ (2003) Joint homeostasis. The discrepancy between old and fresh defects in cartilage repair. J Bone Joint Surg Br 85(7): 1067-1076.
46. Saris DB, Vanlauwe J, Victor J et al (2008) Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med 36(2): 235-246.
47. Saris DB, Vanlauwe J, Victor J et al (2009) Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med 37(1): 10S-19S.
48. Sgaglione NA, Miniaci A, Gillogly SD, Carter TR (2002) Update on advanced surgical techniques in the treatment of traumatic focal articular cartilage lesions in the knee. Arthroscopy 18(2): 9-32.
49. Tallheden T, Bengtsson C, Brantsing C et al (2005) Proliferation and differentiation potential of chondrocytes from osteoarthritic patients. Arthritis Res Ther 7(3): R560-R568.
50. Tegner Y, Lysholm J (1985) Rating systems in the evaluation of knee ligament injuries. Clin Orthop 198: 43-49.
51. Ulrich-Vinther M, Maloney MD, Schwarz EM, Rosier R, O'Keefe RJ (2003) Articular cartilage biology. J Am Acad Orthop Surg 11(6): 421-430.