Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension

Circulation

Volumn 126, Issue 9, 2012, Pages 1099-1109

  Ormiston, Mark L ^a   Chang, Chiwen ^a   Long, Lu L ^a   Soon, Elaine ^a   Jones, Des ^a   Machado, Rajiv ^c   Treacy, Carmen ^d   Toshner, Mark R ^a   Campbell, Kate ^e   Riding, Alex ^a   Southwood, Mark ^e   Pepke Zaba, Joanna ^d   Exley, Andrew ^e   Trembath, Richard C ^c   Colucci, Francesco ^b   Wills, Mark ^a   Trowsdale, John ^a   Morrell, Nicholas W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d Pulmonary Vascular Diseases Unit   (United Kingdom)

^e PAPWORTH HOSPITAL   (United Kingdom)

Author keywords

Immunology; Natural killer cells; Pulmonary hypertension; Transforming growth factor

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; GAMMA INTERFERON; GELATINASE B; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR S1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL FUNCTION; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; DNA POLYMORPHISM; DOWN REGULATION; FLOW CYTOMETRY; GENOTYPE; HLA SYSTEM; HUMAN; HUMAN CELL; HYPOXIA; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RAT; T LYMPHOCYTE SUBPOPULATION; THROMBOEMBOLISM;

ADULT; AGED; ANIMALS; ANTIGENS, CD56; CHEMOKINE CCL4; CYTOTOXICITY, IMMUNOLOGIC; EXTRACELLULAR MATRIX; FEMALE; GENOTYPE; GPI-LINKED PROTEINS; HUMANS; HYPERTENSION, PULMONARY; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MIDDLE AGED; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; PULMONARY EMBOLISM; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IGG; RECEPTORS, KIR2DL1; RECEPTORS, KIR3DL1; RECEPTORS, KIR3DS1; TRANSFORMING GROWTH FACTOR BETA;

EID: 84865498747     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.110619     Document Type: Article

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