Allosteric inhibition of the DNA-dependent ATPase activity of Escherichia coli DNA gyrase by a representative of a novel class of inhibitors

Biochemical Pharmacology

Volumn 84, Issue 7, 2012, Pages 900-904

  Shapiro, Adam B ^a   Andrews, Beth ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

ATPase; Ciprofloxacin; Fluoroquinolone; Gyrase; Inhibitor; Topoisomerase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BACTERIAL DNA; CIPROFLOXACIN; DNA; GYRASE INHIBITOR; QUINOLINE DERIVED ANTIINFECTIVE AGENT; VIQUIDACIN;

ALLOSTERISM; ARTICLE; BINDING SITE; CATALYSIS; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ALLOSTERIC REGULATION; ANTI-BACTERIAL AGENTS; BINDING SITES; CIPROFLOXACIN; DNA GYRASE; ENZYME INHIBITORS; ESCHERICHIA COLI; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84865473314     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.07.007     Document Type: Article

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