Implementation of dose superimposition to introduce multiple doses for a mathematical absorption model (transit compartment model)

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 39, Issue 3, 2012, Pages 251-262

  Shen, Jun ^a   Boeckmann, Alison ^b   Vick, Andrew ^a  

^a Seventh Wave   (United States)

^b ICON Development Solutions   (United States)

Author keywords

Dose superimposition; Mathematical absorption model; Multiple doses; NONMEM; Transit compartment model; WinNonlin

Indexed keywords

DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; CALCULATION; DOSE SUPERIMPOSITION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; MATHEMATICAL ABSORPTION MODEL; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MULTIPLE DRUG DOSE; PHARMACOLOGICAL PARAMETERS; PREDICTION; PRIORITY JOURNAL; SIMULATION; TRANSIT COMPARTMENT MODEL;

ABSORPTION; DOSE-RESPONSE RELATIONSHIP, DRUG; MODELS, BIOLOGICAL; MODELS, THEORETICAL; PHARMACEUTICAL PREPARATIONS;

EID: 84865470874     PISSN: 1567567X     EISSN: 15738744     Source Type: Journal    
DOI: 10.1007/s10928-012-9247-3     Document Type: Article

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