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Volumn 87, Issue 6, 1998, Pages 732-737

Transit compartments versus gamma distribution function to model signal transduction processes in pharmacodynamics

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMPARTMENT MODEL; PHARMACOKINETICS; PROBABILITY; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION; STOCHASTIC MODEL;

EID: 0031835741     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js970414z     Document Type: Article
Times cited : (151)

References (29)
  • 3
    • 0010510049 scopus 로고
    • Nuclear receptor-DNA interactions
    • Tsai, M-J., O'Malley, B. W., Eds.; R. G. Landes Company: Austin, TX
    • Cooney, A. J.; Tsai, S. Y. Nuclear receptor-DNA interactions. In Mechanism of Steroid Hormone Regulation of Gene Transcription; Tsai, M-J., O'Malley, B. W., Eds.; R. G. Landes Company: Austin, TX, 1994; pp 25-59.
    • (1994) Mechanism of Steroid Hormone Regulation of Gene Transcription , pp. 25-59
    • Cooney, A.J.1    Tsai, S.Y.2
  • 5
    • 0017757555 scopus 로고
    • Resolution of some components of adenylate cyclase necessary for catalytic activity
    • Ross, E. M.; Gilman, A. G. Resolution of some components of adenylate cyclase necessary for catalytic activity. J. Biol. Chem. 1977, 252, 6966-6969.
    • (1977) J. Biol. Chem. , vol.252 , pp. 6966-6969
    • Ross, E.M.1    Gilman, A.G.2
  • 6
    • 0344188711 scopus 로고    scopus 로고
    • Evolutions: Steroid-hormone receptor signaling
    • Tingley, D. W. Evolutions: steroid-hormone receptor signaling. J. NIH Res. 1996, 8, 81-88.
    • (1996) J. NIH Res. , vol.8 , pp. 81-88
    • Tingley, D.W.1
  • 7
    • 0028984526 scopus 로고
    • Early signaling events in neutrophils detected by rapid confocal laser scanning
    • Pettit, E. J.; Hallett, M. B. Early signaling events in neutrophils detected by rapid confocal laser scanning. Biochem. J. 1995, 310, 445-448.
    • (1995) Biochem. J. , vol.310 , pp. 445-448
    • Pettit, E.J.1    Hallett, M.B.2
  • 8
    • 0029552810 scopus 로고
    • Third-generation model for corticosteroid pharmacodynamics: Roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver
    • Xu, Z.-X.; Sun, Y.-N.; DuBois, D. C.; Almon, R. R.; Jusko, W. J. Third-generation model for corticosteroid pharmacodynamics: Roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver. J. Pharmacokinet. Biopharm. 1995, 23, 163-181.
    • (1995) J. Pharmacokinet. Biopharm. , vol.23 , pp. 163-181
    • Xu, Z.-X.1    Sun, Y.-N.2    DuBois, D.C.3    Almon, R.R.4    Jusko, W.J.5
  • 9
    • 0014309505 scopus 로고
    • The effect of carbon tetrachloride on the kinetics of bromsulphalein clearance in the rabbit
    • Alfieri-Rolla, G.; Segre, G. The effect of carbon tetrachloride on the kinetics of bromsulphalein clearance in the rabbit. Eur. J. Pharmacol. 1968, 3, 330-336.
    • (1968) Eur. J. Pharmacol. , vol.3 , pp. 330-336
    • Alfieri-Rolla, G.1    Segre, G.2
  • 11
  • 14
    • 0016833554 scopus 로고
    • Platelet kinetics in idiopathic thrombocytopenic purpura (ITP) before and at different times after splenectomy
    • Branehög, I. Platelet kinetics in idiopathic thrombocytopenic purpura (ITP) before and at different times after splenectomy. Br. J. Haematol. 1975, 29, 413-426.
    • (1975) Br. J. Haematol. , vol.29 , pp. 413-426
    • Branehög, I.1
  • 17
    • 77049220618 scopus 로고
    • Affinity and intrinsic activity m the theory of competitive inhibition
    • Ariëns, E. J. Affinity and intrinsic activity m the theory of competitive inhibition. Arch. Int. Pharmacodyn. Ther. 1954, 99, 32-49.
    • (1954) Arch. Int. Pharmacodyn. Ther. , vol.99 , pp. 32-49
    • Ariëns, E.J.1
  • 19
    • 0018394195 scopus 로고
    • Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine
    • Sheiner, L. B.; Stanski, D. R.; Vozeh, S.; Miller, R. D.; Ham, J. Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine. Clin. Pharmacol. Ther. 1979, 25, 358-371.
    • (1979) Clin. Pharmacol. Ther. , vol.25 , pp. 358-371
    • Sheiner, L.B.1    Stanski, D.R.2    Vozeh, S.3    Miller, R.D.4    Ham, J.5
  • 20
    • 0027769745 scopus 로고
    • Comparison of four basic models of indirect pharmacodynamic responses
    • Dayneka, N. L.; Garg, V.; Jusko, W. J. Comparison of four basic models of indirect pharmacodynamic responses. J. Pharmacokinet. Biopharm. 1993, 21, 457-478.
    • (1993) J. Pharmacokinet. Biopharm. , vol.21 , pp. 457-478
    • Dayneka, N.L.1    Garg, V.2    Jusko, W.J.3
  • 21
    • 0028800137 scopus 로고
    • Convergence of direct and indirect pharmacodynamic response models
    • Jusko, W. J.; Ko, H. C.; Ebling, W. F. Convergence of direct and indirect pharmacodynamic response models. J. Pharmacokinet. Biopharm. 1995, 23, 5-8.
    • (1995) J. Pharmacokinet. Biopharm. , vol.23 , pp. 5-8
    • Jusko, W.J.1    Ko, H.C.2    Ebling, W.F.3
  • 22
    • 0024390992 scopus 로고
    • Second generation model for prednisolone pharmacodynamics in the rat
    • Nichols, A. I.; Boudinot, F. D.; Jusko, W. J. Second generation model for prednisolone pharmacodynamics in the rat. J. Pharmacokinet. Biopharm. 1989, 17, 209-227.
    • (1989) J. Pharmacokinet. Biopharm. , vol.17 , pp. 209-227
    • Nichols, A.I.1    Boudinot, F.D.2    Jusko, W.J.3
  • 23
    • 0027288626 scopus 로고
    • Molar quantification of specific messenger ribonucleic acid expression in Northern hybridization using cRNA standards
    • DuBois, D. C.; Almon, R. R.; Jusko, W. J. Molar quantification of specific messenger ribonucleic acid expression in Northern hybridization using cRNA standards. Anal. Biochem. 1993, 210, 140-144.
    • (1993) Anal. Biochem. , vol.210 , pp. 140-144
    • DuBois, D.C.1    Almon, R.R.2    Jusko, W.J.3
  • 24
    • 85030335840 scopus 로고    scopus 로고
    • Fourth-generation model for corticosteroid pharmacodynamics: A model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction m rat liver
    • Unpublished results. submitted
    • Sun, Y.-N.; DuBois, D. C.; Almon, R. R.; Jusko, W. J. Unpublished results. Fourth-generation model for corticosteroid pharmacodynamics: A model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction m rat liver J. Pharmacokin. Biopharm., submitted.
    • J. Pharmacokin. Biopharm.
    • Sun, Y.-N.1    DuBois, D.C.2    Almon, R.R.3    Jusko, W.J.4
  • 25
    • 0024476764 scopus 로고
    • Mechanism of insulin-induced insulin-receptor down-regulation: Decrease of receptor biosynthesis and mRNA levels
    • Okabayashi, Y.; Maddux, B. A.; McDonald, A. R.; Logsdon, C. D.; Williams, J. A.; Goldfine, I. D. Mechanism of insulin-induced insulin-receptor down-regulation: Decrease of receptor biosynthesis and mRNA levels. Diabetes 1989, 38, 182-187.
    • (1989) Diabetes , vol.38 , pp. 182-187
    • Okabayashi, Y.1    Maddux, B.A.2    McDonald, A.R.3    Logsdon, C.D.4    Williams, J.A.5    Goldfine, I.D.6
  • 26
    • 0028812135 scopus 로고
    • Glucose-induced stimulation of human insulin-receptor mRNA and tyrosine kinase activity in cultured cells
    • Hauguel-de-Mouzon, A.; Mrejen, C.; Alengrin, F.; Obberghen, E. V. Glucose-induced stimulation of human insulin-receptor mRNA and tyrosine kinase activity in cultured cells. Biochem. J. 1995, 305, 119-124.
    • (1995) Biochem. J. , vol.305 , pp. 119-124
    • Hauguel-de-Mouzon, A.1    Mrejen, C.2    Alengrin, F.3    Obberghen, E.V.4
  • 27
    • 0024040764 scopus 로고
    • Down-regulation of β-adrenergic receptors: Agonist-induced reduction in receptor mRNA levels
    • Hadcock, J. R.; Malbon, C. C. Down-regulation of β-adrenergic receptors: Agonist-induced reduction in receptor mRNA levels Proc. Natl. Acad. Sci. U.S.A. 1988, 85, 5021-5025.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 5021-5025
    • Hadcock, J.R.1    Malbon, C.C.2
  • 28
    • 0018934044 scopus 로고
    • Elevation of β-adrenergic receptor density in human lymphocytes after propranolol administration
    • Aarons, R. D.; Nies, A. S.; Gal, J.; Hegstrand, L. R.; Molinoff, P. B. Elevation of β-adrenergic receptor density in human lymphocytes after propranolol administration. J. Clin. Invest. 1980, 65, 949-957.
    • (1980) J. Clin. Invest. , vol.65 , pp. 949-957
    • Aarons, R.D.1    Nies, A.S.2    Gal, J.3    Hegstrand, L.R.4    Molinoff, P.B.5
  • 29
    • 0024442891 scopus 로고
    • Drug- or hormone-induced adaptation: Model of adrenergic hypersensitivity
    • Lima, J. J.; Krukemyer, J. J.; Boudoulas, H. Drug-or hormone-induced adaptation: Model of adrenergic hypersensitivity. J. Pharmacokinet. Biopharm. 1989, 17, 347-364.
    • (1989) J. Pharmacokinet. Biopharm. , vol.17 , pp. 347-364
    • Lima, J.J.1    Krukemyer, J.J.2    Boudoulas, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.