-
1
-
-
70350089249
-
Trends in waiting list registration for liver transplantation for viral hepatitis in the United States
-
Kim WR, Terrault NA, Pedersen RA, et al. Trends in waiting list registration for liver transplantation for viral hepatitis in the United States. Gastroenterology. 2009;137:1680-1686.
-
(2009)
Gastroenterology
, vol.137
, pp. 1680-1686
-
-
Kim, W.R.1
Terrault, N.A.2
Pedersen, R.A.3
-
2
-
-
0029914375
-
Long-term outcome of hepatitis C infection after liver transplantation
-
Gane EJ, Portmann BC, Naoumov NV, et al. Long-term outcome of hepatitis C infection after liver transplantation. N Engl J Med. 1996;334:815-820.
-
(1996)
N Engl J Med
, vol.334
, pp. 815-820
-
-
Gane, E.J.1
Portmann, B.C.2
Naoumov, N.V.3
-
3
-
-
0036146088
-
Timing of reinfection and mechanisms of hepatocellular damage in transplanted hepatitis C virus-reinfected liver
-
Ballardini G, De Raffele E, Groff P, et al. Timing of reinfection and mechanisms of hepatocellular damage in transplanted hepatitis C virus-reinfected liver. Liver Transpl. 2002;8:10-20.
-
(2002)
Liver Transpl.
, vol.8
, pp. 10-20
-
-
Ballardini, G.1
De Raffele, E.2
Groff, P.3
-
4
-
-
0034078396
-
Early detection of hepatitis C allograft reinfection after orthotopic liver transplantation: A molecular and histologic study
-
Guerrero RB, Batts KP, Burgart LJ, et al. Early detection of hepatitis C allograft reinfection after orthotopic liver transplantation: A molecular and histologic study. Mod Pathol. 2000;13:229-237.
-
(2000)
Mod Pathol
, vol.13
, pp. 229-237
-
-
Guerrero, R.B.1
Batts, K.P.2
Burgart, L.J.3
-
5
-
-
0036793302
-
Natural history of recurrent hepatitis C
-
Berenguer M. Natural history of recurrent hepatitis C. Liver Transpl. 2002;8:S14-S18.
-
(2002)
Liver Transpl.
, vol.8
-
-
Berenguer, M.1
-
6
-
-
33845488548
-
Clinical and histological efficacy of pegylated interferon and ribavirin therapy of recurrent hepatitis C after liver transplantation
-
Fernandez I, Meneu JC, Colina F, et al. Clinical and histological efficacy of pegylated interferon and ribavirin therapy of recurrent hepatitis C after liver transplantation. Liver Transpl. 2006;12:1805-1812.
-
(2006)
Liver Transpl.
, vol.12
, pp. 1805-1812
-
-
Fernandez, I.1
Meneu, J.C.2
Colina, F.3
-
7
-
-
34250866552
-
Sustained virologic response to therapy of recurrent hepatitis C after liver transplantation is related to early virologic response and dose adherence
-
Sharma P, Marrero JA, Fontana RJ, et al. Sustained virologic response to therapy of recurrent hepatitis C after liver transplantation is related to early virologic response and dose adherence. Liver Transpl. 2007;13:1100-1108.
-
(2007)
Liver Transpl
, vol.13
, pp. 1100-1108
-
-
Sharma, P.1
Marrero, J.A.2
Fontana, R.J.3
-
8
-
-
34247863801
-
Efficacy of antiviral therapy on hepatitis C recurrence after liver transplantation: A randomized controlled study
-
Carrion JA, Navasa M, Garcia-Retortillo M, et al. Efficacy of antiviral therapy on hepatitis C recurrence after liver transplantation: A randomized controlled study. Gastroenterology. 2007;132:1746-1756.
-
(2007)
Gastroenterology
, vol.132
, pp. 1746-1756
-
-
Carrion, J.A.1
Navasa, M.2
Garcia-Retortillo, M.3
-
9
-
-
20444377637
-
Combined treatment with pegylated interferon (a-2b) and ribavirin in the acute phase of hepatitis C virus recurrence after liver transplantation
-
Castells L, Vargas V, Allende H, et al. Combined treatment with pegylated interferon (a-2b) and ribavirin in the acute phase of hepatitis C virus recurrence after liver transplantation. J Hepatol. 2005;43:53-59.
-
(2005)
J Hepatol
, vol.43
, pp. 53-59
-
-
Castells, L.1
Vargas, V.2
Allende, H.3
-
10
-
-
10744233319
-
Treatment of recurrent hepatitis C infection after liver transplantation with combination of pegylated interferon a2b and ribavirin: An open-label series
-
Rodriguez-Luna H, Khatib A, Sharma P, et al. Treatment of recurrent hepatitis C infection after liver transplantation with combination of pegylated interferon a2b and ribavirin: An open-label series. Transplantation. 2004;77: 190-194.
-
(2004)
Transplantation.
, vol.77
, pp. 190-194
-
-
Rodriguez-Luna, H.1
Khatib, A.2
Sharma, P.3
-
11
-
-
1642565346
-
Pegylated interferon a-2b plus ribavirin in the treatment of post-liver transplant recurrent hepatitis C
-
Ross AS, Bhan AK, Pascual M, et al. Pegylated interferon a-2b plus ribavirin in the treatment of post-liver transplant recurrent hepatitis C. Clin Transplant. 2004;18:166-173.
-
(2004)
Clin Transplant
, vol.18
, pp. 166-173
-
-
Ross, A.S.1
Bhan, A.K.2
Pascual, M.3
-
12
-
-
33646813936
-
Impact of pegylated interferon a-2B and ribavirin on hepatic fibrosis in liver transplant patients with recurrent hepatitis C: An open-label series
-
Mukherjee S, Lyden E. Impact of pegylated interferon a-2B and ribavirin on hepatic fibrosis in liver transplant patients with recurrent hepatitis C: An open-label series. Liver Int. 2006;26:529-535.
-
(2006)
Liver Int
, vol.26
, pp. 529-535
-
-
Mukherjee, S.1
Lyden, E.2
-
13
-
-
33846256585
-
Histological benefit of retreatment by pegylated interferon alfa-2b and ribavirin in patients with recurrent hepatitis C virus infection posttransplantation
-
Bizollon T, Pradat P, Mabrut J-Y, et al. Histological benefit of retreatment by pegylated interferon alfa-2b and ribavirin in patients with recurrent hepatitis C virus infection posttransplantation. Am J Transplant. 2007;7:448-453.
-
(2007)
Am J Transplant
, vol.7
, pp. 448-453
-
-
Bizollon, T.1
Pradat, P.2
Mabrut, J.-Y.3
-
14
-
-
8644285360
-
Treatment of established recurrent hepatitis C in liver-transplant recipients with pegylated interferon-alfa-2b and ribavirin therapy
-
Neff GW, Montalbano M, O'Brien CB, et al. Treatment of established recurrent hepatitis C in liver-transplant recipients with pegylated interferon-alfa-2b and ribavirin therapy. Transplantation. 2004;78:1303-1307.
-
(2004)
Transplantation
, vol.78
, pp. 1303-1307
-
-
Neff, G.W.1
Montalbano, M.2
O'Brien, C.B.3
-
15
-
-
34249864417
-
Increasing adherence to therapy for recurrent hepatitis C after liver transplantation by starting at lower drug doses and adding growth factors
-
Rahim N, Prosser C, Bowlus C, et al. Increasing adherence to therapy for recurrent hepatitis C after liver transplantation by starting at lower drug doses and adding growth factors. Pract Gastroenterol. 2007;31:24-33.
-
(2007)
Pract Gastroenterol
, vol.31
, pp. 24-33
-
-
Rahim, N.1
Prosser, C.2
Bowlus, C.3
-
16
-
-
38649139137
-
Recurrent hepatitis C after liver transplantation: On-treatment prediction of response to peginterferon/ribavirin therapy
-
Hanouneh IA, Miller C, Aucejo F, et al. Recurrent hepatitis C after liver transplantation: on-treatment prediction of response to peginterferon/ribavirin therapy. Liver Transpl. 2008;14: 53-58.
-
(2008)
Liver Transpl.
, vol.14
, pp. 53-58
-
-
Hanouneh, I.A.1
Miller, C.2
Aucejo, F.3
-
17
-
-
0037371521
-
Interferon-A 2b plus ribavirin in patients with chronic hepatitis C after liver transplantation: A randomized study
-
Samuel D, Bizollon T, Feray C, et al. Interferon-a 2b plus ribavirin in patients with chronic hepatitis C after liver transplantation: A randomized study. Gastroenterology. 2003; 124:642-650.
-
(2003)
Gastroenterology
, vol.124
, pp. 642-650
-
-
Samuel, D.1
Bizollon, T.2
Feray, C.3
-
18
-
-
46349089961
-
Systematic review of the treatment of established recurrent hepatitis C with pegylated interferon in combination with ribavirin
-
Berenguer M. Systematic review of the treatment of established recurrent hepatitis C with pegylated interferon in combination with ribavirin. J Hepatol. 2008;49:274-287.
-
(2008)
J Hepatol
, vol.49
, pp. 274-287
-
-
Berenguer, M.1
-
19
-
-
11844249361
-
Applicability, tolerability and efficacy of preemptive antiviral therapy in hepatitis C-infected patients undergoing liver transplantation
-
Shergill AK, Khalili M, Straley S, et al. Applicability, tolerability and efficacy of preemptive antiviral therapy in hepatitis C-infected patients undergoing liver transplantation. Am J Transplant. 2005;5:118-124.
-
(2005)
Am J Transplant.
, vol.5
, pp. 118-124
-
-
Shergill, A.K.1
Khalili, M.2
Straley, S.3
-
20
-
-
3242772980
-
Effects of interferon treatment on liver histology and allograft rejection in patients with recurrent hepatitis C following liver transplantation
-
Stravitz RT, Shiffman ML, Sanyal AJ, et al. Effects of interferon treatment on liver histology and allograft rejection in patients with recurrent hepatitis C following liver transplantation. Liver Transpl. 2004;10:850-858.
-
(2004)
Liver Transpl
, vol.10
, pp. 850-858
-
-
Stravitz, R.T.1
Shiffman, M.L.2
Sanyal, A.J.3
-
21
-
-
19944430229
-
Peginterferon alfa-2a for hepatitis C after liver transplantation: Two randomized, controlled trials
-
Chalasani N, Manzarbeitia C, Ferenci P, et al. Peginterferon alfa-2a for hepatitis C after liver transplantation: Two randomized, controlled trials. Hepatology. 2005;41:289-298.
-
(2005)
Hepatology
, vol.41
, pp. 289-298
-
-
Chalasani, N.1
Manzarbeitia, C.2
Ferenci, P.3
-
22
-
-
23044500773
-
Treatment of advanced hepatitis C with a low accelerating dosage regimen of antiviral therapy
-
Everson GT, Trotter J, Forman L, et al. Treatment of advanced hepatitis C with a low accelerating dosage regimen of antiviral therapy. Hepatology. 2005;42:255-262.
-
(2005)
Hepatology
, vol.42
, pp. 255-262
-
-
Everson, G.T.1
Trotter, J.2
Forman, L.3
-
23
-
-
58249086156
-
Hepatitis C virus therapy in liver transplant recipients: Response predictors, effect on fibrosis progression, and importance of the initial stage of fibrosis
-
Roche B, Sebagh M, Canfora ML, et al. Hepatitis C virus therapy in liver transplant recipients: Response predictors, effect on fibrosis progression, and importance of the initial stage of fibrosis. Liver Transpl. 2008;14:1766-1777.
-
(2008)
Liver Transpl.
, vol.14
, pp. 1766-1777
-
-
Roche, B.1
Sebagh, M.2
Canfora, M.L.3
-
24
-
-
33748497126
-
Hepatitis C recurrence after liver transplantation: Viral and histologic response to full-dose PEG-interferon and ribavirin
-
Oton E, Barcena R, Moreno-Planas JM, et al. Hepatitis C recurrence after liver transplantation: viral and histologic response to full-dose PEG-interferon and ribavirin. Am J Transplant. 2006;6:2348-2355.
-
(2006)
Am J Transplant.
, vol.6
, pp. 2348-2355
-
-
Oton, E.1
Barcena, R.2
Moreno-Planas, J.M.3
-
25
-
-
33745997054
-
Efficacy, predictors of response, and potential risks associated with antiviral therapy in liver transplant recipients with recurrent hepatitis C
-
Berenguer M, Palau A, Fernandez A, et al. Efficacy, predictors of response, and potential risks associated with antiviral therapy in liver transplant recipients with recurrent hepatitis C. Liver Transpl. 2006;12:1067-1076.
-
(2006)
Liver Transpl.
, vol.12
, pp. 1067-1076
-
-
Berenguer, M.1
Palau, A.2
Fernandez, A.3
-
26
-
-
33645911783
-
Evaluation of the antihepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811
-
Goto K, Watashi K, Murata T, et al. Evaluation of the antihepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811. Biochem Biophys Res Commun. 2006;343:879-884.
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 879-884
-
-
Goto, K.1
Watashi, K.2
Murata, T.3
-
27
-
-
33645106470
-
Cyclosporine suppresses hepatitis C virus in vitro and increases the chance of a sustained virological response after liver transplantation
-
Firpi RJ, Zhu H, Morelli G, et al. Cyclosporine suppresses hepatitis C virus in vitro and increases the chance of a sustained virological response after liver transplantation. Liver Transpl. 2006;12:51-57.
-
(2006)
Liver Transpl
, vol.12
, pp. 51-57
-
-
Firpi, R.J.1
Zhu, H.2
Morelli, G.3
-
28
-
-
73849094005
-
Antiviral treatment of recurrent hepatitis C after liver transplantation: Predictors of response and long-term outcome
-
Selzner N, Renner EL, Selzner M, et al. Antiviral treatment of recurrent hepatitis C after liver transplantation: Predictors of response and long-term outcome. Transplantation. 2009;88: 1214-1221.
-
(2009)
Transplantation
, vol.88
, pp. 1214-1221
-
-
Selzner, N.1
Renner, E.L.2
Selzner, M.3
-
29
-
-
74049157660
-
The use of cyclosporine for recurrent hepatitis C after liver transplant: A randomized pilot study
-
Firpi RJ, Soldevila-Pico C, Morelli GG, et al. The use of cyclosporine for recurrent hepatitis C after liver transplant: A randomized pilot study. Dig Dis Sci. 2010;55:196-203.
-
(2010)
Dig Dis Sci
, vol.55
, pp. 196-203
-
-
Firpi, R.J.1
Soldevila-Pico, C.2
Morelli, G.G.3
-
30
-
-
0242437747
-
Once-weekly epoetin alfa improves anemia and facilitates maintenance of ribavirin dosing in hepatitis C virus-infected patients receiving ribavirin plus interferon alfa
-
Dieterich DT, Wasserman R, Brau N, et al. Once-weekly epoetin alfa improves anemia and facilitates maintenance of ribavirin dosing in hepatitis C virus-infected patients receiving ribavirin plus interferon alfa. Am J Gastroenterol. 2003;98:2491-2499.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 2491-2499
-
-
Dieterich, D.T.1
Wasserman, R.2
Brau, N.3
-
31
-
-
11144358403
-
Epoetin alfa maintains ribavirin dose in HCV-infected patients: A prospective, double-blind, randomized controlled study
-
Afdhal NH, Dieterich DT, Pockros PJ, et al. Epoetin alfa maintains ribavirin dose in HCV-infected patients: A prospective, double-blind, randomized controlled study. Gastroenterology. 2004;126:1302-1311.
-
(2004)
Gastroenterology
, vol.126
, pp. 1302-1311
-
-
Afdhal, N.H.1
Dieterich, D.T.2
Pockros, P.J.3
-
32
-
-
79959549897
-
Telaprevir, boceprevir, cytochrome P450 and immunosuppressive agents - A potentially lethal cocktail
-
Charlton M. Telaprevir, boceprevir, cytochrome P450 and immunosuppressive agents - a potentially lethal cocktail. Hepatology. 2011;54:3-5. 637-648
-
(2011)
Hepatology
, vol.54
, pp. 637-648
-
-
Charlton, M.1
-
33
-
-
84873573110
-
Globocan 2008 v1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No 10 (GLOBOCAN web site)
-
Available at Accessed September 22, 2011
-
Ferlay J, Shin HR, Bray F, et al. GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 (GLOBOCAN web site). Lyon, France International Agency for Research on Cancer; 2010. Available at: http:// globocan.iarc.fr. Accessed September 22, 2011.
-
(2010)
Lyon France International Agency for Research on Cancer
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
-
34
-
-
77952002277
-
Gastric cancer: A primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease
-
Shah MA, Kelsen DP. Gastric cancer: A primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease. J Natl Compr Canc Netw. 2010;8:437-447.
-
(2010)
J Natl Compr Canc Netw
, vol.8
, pp. 437-447
-
-
Shah, M.A.1
Kelsen, D.P.2
-
35
-
-
20944437877
-
Survival after gastric adenocarcinoma resection: Eighteen-year experience at a single institution
-
Cunningham SC, Kamangar F, Kim MP, et al. Survival after gastric adenocarcinoma resection: Eighteen-year experience at a single institution. J Gastrointest Surg. 2010;9:718-725.
-
(2010)
J Gastrointest Surg
, vol.9
, pp. 718-725
-
-
Cunningham, S.C.1
Kamangar, F.2
Kim, M.P.3
-
37
-
-
33646568784
-
Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
-
Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world. J ClinOncol. 2006;24:2137-2150.
-
(2006)
J ClinOncol
, vol.24
, pp. 2137-2150
-
-
Kamangar, F.1
Dores, G.M.2
Anderson, W.F.3
-
38
-
-
78650115024
-
Against Cancer Classification of gastric adenocarcinoma in comparison with the sixth classification
-
Evaluation Of The Seventh American Joint Committee On CancerInternational Union
-
Ahn HS, Lee HJ, Hahn S, et al. Evaluation of the seventh American Joint Committee on Cancer/International Union Against Cancer Classification of gastric adenocarcinoma in comparison with the sixth classification. Cancer. 2010;116: 5592-5598.
-
(2010)
Cancer.
, Issue.116
, pp. 5592-5598
-
-
Ahn, H.S.1
Lee, H.J.2
Hahn, S.3
-
39
-
-
22344438694
-
Epidemiology of gastric cancer in Japan
-
Inoue M, Tsugane S. Epidemiology of gastric cancer in Japan. Postgrad Med J. 2005;81:419-424.
-
(2005)
Postgrad Med J
, vol.81
, pp. 419-424
-
-
Inoue, M.1
Tsugane, S.2
-
40
-
-
0027217474
-
Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer
-
Murad AM, Santiago FF, Petroianu A, et al. Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer. Cancer. 1993;72:37-41.
-
(1993)
Cancer
, vol.72
, pp. 37-41
-
-
Murad, A.M.1
Santiago, F.F.2
Petroianu, A.3
-
41
-
-
79960752090
-
Our experiences of best supportive care for gastric cancer patients
-
(in Japanese with English abstract)
-
Shimoyama S, Itouji T, Enomoto H, et al. Our experiences of best supportive care for gastric cancer patients (in Japanese with English abstract). Gan To Kagaku Ryoho. 2010;37: 259-262.
-
(2010)
Gan To Kagaku Ryoho
, vol.37
, pp. 259-262
-
-
Shimoyama, S.1
Itouji, T.2
Enomoto, H.3
-
42
-
-
79957997894
-
Chemotherapy in the treatment of metastatic gastric cancer: Is there a global standard?
-
Kang H, Kauh JS. Chemotherapy in the treatment of metastatic gastric cancer: is there a global standard? Curr Treat Options Oncol. 2011;12:96-106.
-
(2011)
Curr Treat Options Oncol
, vol.12
, pp. 96-106
-
-
Kang, H.1
Kauh, J.S.2
-
45
-
-
40749153540
-
S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial
-
Koizumi W, Narahara H, Hara T, et al. S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial. Lancet Oncol. 2008;9:215-221.
-
(2008)
Lancet Oncol
, vol.9
, pp. 215-221
-
-
Koizumi, W.1
Narahara, H.2
Hara, T.3
-
46
-
-
38049047178
-
Capecitabine and oxaliplatin for advanced esophagogastric cancer
-
Cunningham D, Starling N, Rao S, et al. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N Engl J Med. 2008;358:36-46.
-
(2008)
N Engl J Med.
, vol.358
, pp. 36-46
-
-
Cunningham, D.1
Starling, N.2
Rao, S.3
-
47
-
-
63749118193
-
Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: A randomised phase III noninferiority trial
-
Kang YK, Kang WK, Shin DB, et al. Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: A randomised phase III noninferiority trial. Ann Oncol. 2009;20:666-673.
-
(2009)
Ann Oncol
, vol.20
, pp. 666-673
-
-
Kang, Y.K.1
Kang, W.K.2
Shin, D.B.3
-
48
-
-
63749096474
-
Meta-analysis of the REAL-2 and ML17032 trials: Evaluating capecitabine-based combination chemotherapy and infused 5-fluorouracil-based combination chemotherapy for the treatment of advanced oesophago-gastric cancer
-
Okines AF, Norman AR,McCloud P, et al.Meta-analysis of the REAL-2 and ML17032 trials: Evaluating capecitabine-based combination chemotherapy and infused 5-fluorouracil-based combination chemotherapy for the treatment of advanced oesophago-gastric cancer. Ann Oncol. 2009;20:1529-1534.
-
(2009)
Ann Oncol
, vol.20
, pp. 1529-1534
-
-
Okines, A.F.1
Norman, A.R.2
McCloud, P.3
-
49
-
-
33750949065
-
Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: A report of the V325 Study Group
-
Van Cutsem E, Moiseyenko VM, Tjulandin S, et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: A report of the V325 Study Group. J Clin Oncol. 2006;24:4991-4997.
-
(2006)
J Clin Oncol.
, vol.24
, pp. 4991-4997
-
-
Van Cutsem, E.1
Moiseyenko, V.M.2
Tjulandin, S.3
-
50
-
-
50849123421
-
HER2 in gastric cancer: A new prognostic factor and a novel therapeutic target
-
Gravalos C, Jimeno A. HER2 in gastric cancer: A new prognostic factor and a novel therapeutic target. Ann Oncol. 2008;19:1523-1529.
-
(2008)
Ann Oncol
, vol.19
, pp. 1523-1529
-
-
Gravalos, C.1
Jimeno, A.2
-
51
-
-
77955479419
-
Combined detection of Her2/neu gene amplification and protein overexpression in effusions from patients with breast and ovarian cancer
-
Schluter B, Gerhards R, Strumberg D, et al. Combined detection of Her2/neu gene amplification and protein overexpression in effusions from patients with breast and ovarian cancer. J Cancer Res Clin Oncol. 2010;136:1389-1400.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 1389-1400
-
-
Schluter, B.1
Gerhards, R.2
Strumberg, D.3
-
52
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987;235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
53
-
-
79953824572
-
HER2 expression in gastric cancer in Peru
-
(in Spanish with English abstract)
-
Beltran GB, Yabar BA. HER2 expression in gastric cancer in Peru (in Spanish with English abstract). Rev Gastroenterol Peru. 2010;30:324-327.
-
(2010)
Rev Gastroenterol Peru
, vol.30
, pp. 324-327
-
-
Beltran, G.B.1
Yabar, B.A.2
-
54
-
-
44249092320
-
Assessment of a HER2 scoring system for gastric cancer: Results from a validation study
-
Hofmann M, Stoss O, Shi D, et al. Assessment of a HER2 scoring system for gastric cancer: Results from a validation study. Histopathology. 2008;52:797-805.
-
(2008)
Histopathology
, vol.52
, pp. 797-805
-
-
Hofmann, M.1
Stoss, O.2
Shi, D.3
-
55
-
-
79958066203
-
Clinicopathologic characteristics of patients with stage III/IV (M(0)) advanced gastric cancer, according to HER2 status assessed by immunohistochemistry and fluorescence in situ hybridization
-
Im SA, Kim JW, Kim JS, et al. Clinicopathologic characteristics of patients with stage III/IV (M(0)) advanced gastric cancer, according to HER2 status assessed by immunohistochemistry and fluorescence in situ hybridization. Diagn Mol Pathol. 2011;20:94-100.
-
(2011)
Diagn Mol Pathol
, vol.20
, pp. 94-100
-
-
Im, S.A.1
Kim, J.W.2
Kim, J.S.3
-
56
-
-
20044372721
-
Amplification of HER-2 in gastric carcinoma: Association with topoisomerase II alpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab
-
Tanner M, Hollme'n M, Junttila TT, et al. Amplification of HER-2 in gastric carcinoma: Association with topoisomerase II alpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab. Ann Oncol. 2005;16:273-278.
-
(2005)
Ann Oncol
, vol.16
, pp. 273-278
-
-
Tanner, M.1
Hollme'n, M.2
Junttila, T.T.3
-
58
-
-
77749273477
-
HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value - conclusions from 924 cases of two independent series
-
Grabsch H, Sivakumar S, Gray S, et al. HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value - conclusions from 924 cases of two independent series. Cell Oncol. 2010;32:57-65.
-
(2010)
Cell Oncol
, vol.32
, pp. 57-65
-
-
Grabsch, H.1
Sivakumar, S.2
Gray, S.3
-
59
-
-
80055001527
-
Her-2/neu gene amplification and over-expression in stomach and esophageal adenocarcinoma: from pathology to treatment
-
Epub ahead of print]
-
Maresch J, Schoppmann SF, Thallinger CM, et al. Her-2/neu gene amplification and over-expression in stomach and esophageal adenocarcinoma: from pathology to treatment. Crit Rev Oncol Hematol. 2011. [Epub ahead of print].
-
(2011)
Crit Rev Oncol Hematol.
-
-
Maresch, J.1
Schoppmann, S.F.2
Thallinger, C.M.3
-
60
-
-
34347395733
-
Trastuzumab - mechanism of action and use in clinical practice
-
Hudis CA. Trastuzumab - mechanism of action and use in clinical practice. N Engl J Med. 2007;357:39-51.
-
(2007)
N Engl J Med
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
61
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001;344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
62
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med. 2005;353:1659-1672.
-
(2005)
N Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
63
-
-
84872651746
-
Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients: BCIRG 006 study. San Antonio Breast Cancer Symposium
-
Slamon D, Eiermann W, Robert N, et al. Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients: BCIRG 006 study. San Antonio Breast Cancer Symposium, 2009; San Antonio, TX, abstract 62.
-
(2009)
San Antonio, TX, abstract 62
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
64
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J, et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med. 2005;353:1673-1684.
-
(2005)
N Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
66
-
-
73349085919
-
Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer
-
Spector NL, Blackwell KL. Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol. 2009;27:5838-5847.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5838-5847
-
-
Spector, N.L.1
Blackwell, K.L.2
-
67
-
-
42449156456
-
Phase II of trastuzumab and cisplatin in patients (pts) with advanced gastric cancer (AGC) with HER2/neu overexpression/amplification
-
Abstract 4613
-
Corte's-Funes H, Rivera F, Alé s I, et al. Phase II of trastuzumab and cisplatin in patients (pts) with advanced gastric cancer (AGC) with HER2/neu overexpression/amplification. J Clin Oncol. 2007;18S. Abstract 4613.
-
(2007)
J Clin Oncol.
-
-
Corte's-Funes, H.1
Rivera, F.2
Alé, S.I.3
-
68
-
-
67650395446
-
Early results of a trial of trastuzumab, cisplatin, and docetaxel (TCD) for the treatment of metastatic gastric cancer overexpressing HER-2
-
Istanbul, Turkey, abstract 1105P
-
Nicholas G, Cripps C, Au H-J, et al. Early results of a trial of trastuzumab, cisplatin, and docetaxel (TCD) for the treatment of metastatic gastric cancer overexpressing HER-2. European Society for Medical Oncology Meeting, 2006; Istanbul, Turkey, abstract 1105P.
-
(2006)
European Society for Medical Oncology Meeting
-
-
Nicholas, G.1
Cripps, C.2
Au, H.-J.3
-
69
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet. 2010;376:687-697.
-
(2010)
Lancet
, Issue.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
-
70
-
-
77954216167
-
Quality of life results from a phase III trial of trastuzumab plus chemotherapy in first-line HER2-positive advanced gastric and GE junction cancer
-
Orlando, FL, abstract 7
-
Satoh T, Leon J, Lopez RI, et al. Quality of life results from a phase III trial of trastuzumab plus chemotherapy in first-line HER2-positive advanced gastric and GE junction cancer. ASCO Gastrointestinal Cancers Symposium, 2010; Orlando, FL, abstract 7.
-
(2010)
ASCO Gastrointestinal Cancers Symposium
-
-
Satoh, T.1
Leon, J.2
Lopez, R.I.3
-
71
-
-
84872663778
-
Self-rated pain assessment by patients with HER2-positive advanced gastric/ GEJ cancer treated with 5-FU/capecitabine and cisplatin with or without trastuzumab: Exploratory QOL analysis from the Phase III ToGA study
-
Kang Y-K, Shen L, Lichinitser M, et al. Self-rated pain assessment by patients with HER2-positive advanced gastric/ GEJ cancer treated with 5-FU/capecitabine and cisplatin with or without trastuzumab: Exploratory QOL analysis from the Phase III ToGA study. Gastroenterology. 2011;140:S-204.
-
(2011)
Gastroenterology.
-
-
Kang, Y.-K.1
Shen, L.2
Lichinitser, M.3
-
72
-
-
0031972496
-
Interpreting the significance of changes in health-related quality-of-life scores
-
Osoba D, Rodrigues G, Myles J, et al. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol. 1998;16:139-144.
-
(1998)
J Clin Oncol
, vol.16
, pp. 139-144
-
-
Osoba, D.1
Rodrigues, G.2
Myles, J.3
-
74
-
-
0024462761
-
A quality-of-lifeoriented endpoint for comparing therapies
-
Gelber RD, Gelman RS, Goldhirsch A. A quality-of-lifeoriented endpoint for comparing therapies. Biometrics. 1989; 45:781-795.
-
(1989)
Biometrics.
, vol.45
, pp. 781-795
-
-
Gelber, R.D.1
Gelman, R.S.2
Goldhirsch, A.3
-
76
-
-
79954436118
-
Q-TWIST analysis of trastuzumab plus fluoropyrimidine/cisplatin (T-XP/ FP) versus XP/FP alone as first-line therapy for advanced HER2-positive gastric cancer
-
Abstract 4048
-
Chung HC, Bang Y-J, Van Cutsem E, et al. (Q)-TWIST analysis of trastuzumab plus fluoropyrimidine/cisplatin (T-XP/ FP) versus XP/FP alone as first-line therapy for advanced HER2-positive gastric cancer. J Clin Oncol. 2010;28. Abstract 4048.
-
(2010)
J Clin Oncol.
, pp. 28
-
-
Chung, H.C.1
Bang, Y.-J.2
Van Cutsem, E.3
-
77
-
-
79251532001
-
Determining the HER2 status in gastric cancer: A method comparison study of two patient cohorts
-
Orlando, FL, abstract 17
-
Powell WC, Zielinski D, Ranger-Moore J, et al. Determining the HER2 status in gastric cancer: A method comparison study of two patient cohorts. ASCO Gastrointestinal Cancers Symposium, 2010; Orlando, FL, abstract 17.
-
(2010)
ASCO Gastrointestinal Cancers Symposium
-
-
Powell, W.C.1
Zielinski, D.2
Ranger-Moore, J.3
-
78
-
-
84872672686
-
Herceptin summary of product characteristics
-
Available at
-
Herceptin summary of product characteristics. Available at: http://www.ema.europa.eu/docs/en-GB/document-library/ EPAR-Product-Information/ human/000278/WC500074922. pdf. Accessed September 22, 2011.
-
(2011)
Accessed September
, vol.22
-
-
-
80
-
-
84872658328
-
-
Accessed September Available at 26
-
Herceptin prescribing information. Available at: http:// www.accessdata.fda.gov/drugsatfda-docs/label/2010/103792s5 256lbl.pdf. Accessed September 26, 2011.
-
(2011)
Herceptin Prescribing Information
-
-
-
82
-
-
80054057131
-
Southwest Oncology Group study S0413: A phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer
-
Iqbal S, Goldman B, Fenoglio-Preiser CM, et al. Southwest Oncology Group study S0413: A phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer. Ann Oncol. 2011;22:2610-2615.
-
(2011)
Ann Oncol
, vol.22
, pp. 2610-2615
-
-
Iqbal, S.1
Goldman, B.2
Fenoglio-Preiser, C.M.3
-
83
-
-
74549210351
-
Lapatinib: A small-molecule inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor-2 tyrosine kinases used in the treatment of breast cancer
-
Tevaarwerk AJ, Kolesar JM. Lapatinib: A small-molecule inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor-2 tyrosine kinases used in the treatment of breast cancer. Clin Ther. 2009;31:2332-2348.
-
(2009)
Clin Ther
, vol.31
, pp. 2332-2348
-
-
Tevaarwerk, A.J.1
Kolesar, J.M.2
-
84
-
-
0035874981
-
Trastuzumab (Herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
-
Molina MA, Codony-Servat J, Albanell J, et al. Trastuzumab (Herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res. 2001;61:4744-4749.
-
(2001)
Cancer Res
, vol.61
, pp. 4744-4749
-
-
Molina, M.A.1
Codony-Servat, J.2
Albanell, J.3
-
85
-
-
49449112267
-
Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain
-
Gril B, Palmieri D, Bronder JL, et al. Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain. J Natl Cancer Inst. 2008;100:1092-1103.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1092-1103
-
-
Gril, B.1
Palmieri, D.2
Bronder, J.L.3
-
86
-
-
42949112556
-
Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer
-
Lin NU, Carey LA, Younger J, et al. Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol. 2008;26:1993-1999.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 1993-1999
-
-
Lin, N.U.1
Carey, L.A.2
Younger, J.3
-
87
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
Geyer CE, Forster J, Lindquist D, et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med. 2006;355:2733-2743.
-
(2006)
N Engl J Med
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
88
-
-
77955096969
-
Lapatinib and HER2 status: Results of a meta-analysis of randomized phase III trials in metastatic breast cancer
-
Amir E, Ocana A, Seruga B, et al. Lapatinib and HER2 status: Results of a meta-analysis of randomized phase III trials in metastatic breast cancer. Cancer Treat Rev. 2010;36: 410-415.
-
(2010)
Cancer Treat Rev.
, Issue.36
, pp. 410-415
-
-
Amir, E.1
Ocana, A.2
Seruga, B.3
-
89
-
-
77951298743
-
Survival benefits from lapatinib therapy in women with HER2-overexpressing breast cancer: A systematic review
-
Yip AY, Tse LA, Ong EY, et al. Survival benefits from lapatinib therapy in women with HER2-overexpressing breast cancer: A systematic review. Anticancer Drugs. 2010;21:487-493.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 487-493
-
-
Yip, A.Y.1
Tse, L.A.2
Ong, E.Y.3
-
90
-
-
84872666409
-
LOGiC - lapatinib optimization study in ErbB2 (HER2) positive gastric cancer: A phase III global, blinded study designed to evaluate clinical endpoints and safety of chemotherapy plus lapatinib
-
Available at
-
LOGiC - lapatinib optimization study in ErbB2 (HER2) positive gastric cancer: A phase III global, blinded study designed to evaluate clinical endpoints and safety of chemotherapy plus lapatinib. Available at: http://clinicaltrials.gov/ct2/show/NCT00680901. Accessed September 22, 2011.
-
(2011)
Accessed September
, vol.22
-
-
-
91
-
-
84872659874
-
A phase III study of CapeOx +/lapatinib in HER2 positive locally advanced/ metastatic upper gastrointestinal adenocarcinoma: Interim safety results
-
Berlin, Germany, poster 6.584
-
Hecht J, Bang Y-J, Sobrero A, et al. A phase III study of CapeOx +/lapatinib in HER2 positive locally advanced/ metastatic upper gastrointestinal adenocarcinoma: interim safety results. European Society for Medical Oncology Meeting 2009; Berlin, Germany, poster 6.584.
-
(2009)
European Society for Medical Oncology Meeting
-
-
Hecht, J.1
Bang, Y.-J.2
Sobrero, A.3
-
93
-
-
79960081156
-
Interim safety analysis from TYTAN: A phase III Asian study of lapatinib in combination with paclitaxel as second-line therapy in gastric cancer
-
Abstract 4057
-
Satoh T, Bang Y, Wang J, et al. Interim safety analysis from TYTAN: A phase III Asian study of lapatinib in combination with paclitaxel as second-line therapy in gastric cancer. J Clin Oncol. 2010;28. Abstract 4057.
-
(2010)
J Clin Oncol.
, pp. 28
-
-
Satoh, T.1
Bang, Y.2
Wang, J.3
-
94
-
-
67651174452
-
Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization
-
Hughes JB, Berger C, Rodland MS, et al. Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization. Mol Cancer Ther. 2009;8:1885-1892.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1885-1892
-
-
Hughes, J.B.1
Berger, C.2
Rodland, M.S.3
-
95
-
-
77949903478
-
Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
-
Baselga J, Gelmon KA, Verma S, et al. Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy. J Clin Oncol. 2010;28:1138-1144.
-
(2010)
J Clin Oncol.
, Issue.28
, pp. 1138-1144
-
-
Baselga, J.1
Gelmon, K.A.2
Verma, S.3
-
96
-
-
84872670831
-
A Study of pertuzumab in combination with trastuzumab and chemotherapy in patients with HER2-positive advanced gastric
-
Available at
-
A Study of pertuzumab in combination with trastuzumab and chemotherapy in patients with HER2-positive advanced gastric cancer. Available at: http://clinicaltrials.gov/ct2/show/ NCT01461057. Accessed February 23, 2012.
-
Cancer
, vol.23
, pp. 2012
-
-
-
97
-
-
56449129810
-
Targeting HER2- positive breast cancer with trastuzumab-DM1, an antibodycytotoxic drug conjugate
-
Lewis Phillips GD, Li G, Dugger DL, et al. Targeting HER2- positive breast cancer with trastuzumab-DM1, an antibodycytotoxic drug conjugate. Cancer Res. 2008;68:9280-9290.
-
(2008)
Cancer Res
, vol.68
, pp. 9280-9290
-
-
Lewis Phillips, G.D.1
Li, G.2
Dugger, D.L.3
-
98
-
-
79959700509
-
Trastuzumab-DM1 (TDM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer
-
Junttila TT, Li G, Parsons K, et al. Trastuzumab-DM1 (TDM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer. Breast Cancer Res Treat. 2010;128:347-356.
-
(2010)
Breast Cancer Res Treat
, vol.128
, pp. 347-356
-
-
Junttila, T.T.1
Li, G.2
Parsons, K.3
-
99
-
-
84872648176
-
Trastuzumab emtansine (TDM1) versus trastuzumab plus docetaxel (H+T) in previouslyuntreated HER2-positive metastatic breast cancer (MBC): Primary results of a randomized, multicenter, open-label phase II study (TDM4450g/BO21976)
-
Milan, Italy, abstract 5001
-
Hurvitz S, Dirix L, Kocsis J, et al. Trastuzumab emtansine (TDM1) versus trastuzumab plus docetaxel (H+T) in previouslyuntreated HER2-positive metastatic breast cancer (MBC): Primary results of a randomized, multicenter, open-label phase II study (TDM4450g/BO21976). European Society for Medical Oncology Meeting, 2010; Milan, Italy, abstract 5001.
-
(2010)
European Society for Medical Oncology Meeting
-
-
Hurvitz, S.1
Dirix, L.2
Kocsis, J.3
-
100
-
-
84872672728
-
Efficacy and safety of trastuzumab-DM1 versus trastuzumab plus docetaxel in HER2- positive metastatic breast cancer patients with no prior chemotherapy for metastatic disease: Preliminary results of a randomized, multicenter, open-label phase 2 study
-
Milan, Italy, abstract LBA3
-
Perez EA, Dirix L, Kocsis J, et al. Efficacy and safety of trastuzumab-DM1 versus trastuzumab plus docetaxel in HER2- positive metastatic breast cancer patients with no prior chemotherapy for metastatic disease: Preliminary results of a randomized, multicenter, open-label phase 2 study. European Society for Medical Oncology Meeting, 2010; Milan, Italy, abstract LBA3.
-
(2010)
European Society for Medical Oncology Meeting
-
-
Perez, E.A.1
Dirix, L.2
Kocsis, J.3
-
101
-
-
84872664212
-
-
Anti-cancer agent, Herceptins obtained approval for additional indication of advanced or recurrent gastric cancer overexpressing HER2, not amenable to curative resection. Available at Accessed September 22
-
Chugai (press release). Anti-cancer agent, Herceptins obtained approval for additional indication of advanced or recurrent gastric cancer overexpressing HER2, not amenable to curative resection. Available at: http://www.chugai- pharm.co. jp/hc/ss/english/news/detail/20110310150000.html. Accessed September 22, 2011.
-
(2011)
Chugai (Press Release)
-
-
-
102
-
-
35148885729
-
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
-
Berns K, Horlings HM, Hennessy BT, et al. A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer. Cancer Cell. 2007;12:395-402.
-
(2007)
Cancer Cell.
, vol.12
, pp. 395-402
-
-
Berns, K.1
Horlings, H.M.2
Hennessy, B.T.3
-
103
-
-
0035915421
-
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu Y, Zi X, Zhao Y, et al. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst. 2001;93:1852-1857.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1852-1857
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
-
104
-
-
33846552656
-
Escape from HERfamily tyrosine kinase inhibitor therapy by the kinaseinactive HER3
-
Sergina NV, Rausch M, Wang D, et al. Escape from HERfamily tyrosine kinase inhibitor therapy by the kinaseinactive HER3. Nature. 2007;445:437-441.
-
(2007)
Nature
, vol.445
, pp. 437-441
-
-
Sergina, N.V.1
Rausch, M.2
Wang, D.3
-
105
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan KH, Zhou X, et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell. 2004;6:117-127.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
-
106
-
-
3543146052
-
Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer
-
Kostler WJ, Schwab B, Singer CF, et al. Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer. Clin Cancer Res. 2004;10:1618-1624.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1618-1624
-
-
Kostler, W.J.1
Schwab, B.2
Singer, C.F.3
-
107
-
-
0026071364
-
The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3
-
Zabrecky JR, Lam T, McKenzie SJ, et al. The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J Biol Chem. 1991;266: 1716-1720.
-
(1991)
J Biol Chem
, vol.266
, pp. 1716-1720
-
-
Zabrecky, J.R.1
Lam, T.2
McKenzie, S.J.3
-
108
-
-
12544250996
-
Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptinresistant, MUC4-expressing breast cancer cell line
-
Nagy P, Friedlander E, Tanner M, et al. Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptinresistant, MUC4-expressing breast cancer cell line. Cancer Res. 2005;65:473-482.
-
(2005)
Cancer Res.
, vol.65
, pp. 473-482
-
-
Nagy, P.1
Friedlander, E.2
Tanner, M.3
-
109
-
-
0037142184
-
Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance
-
Price-Schiavi SA, Jepson S, Li P, et al. Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance. Int J Cancer. 2002;99:783-791.
-
(2002)
Int J Cancer
, vol.99
, pp. 783-791
-
-
Price-Schiavi, S.A.1
Jepson, S.2
Li, P.3
-
110
-
-
42949157368
-
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neupositive metastatic breast cancer
-
Musolino A, Naldi N, Bortesi B, et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neupositive metastatic breast cancer. J Clin Oncol. 2008;26: 1789-1796.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 1789-1796
-
-
Musolino, A.1
Naldi, N.2
Bortesi, B.3
-
111
-
-
77949884661
-
Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer
-
Blackwell KL, Burstein HJ, Storniolo AM, et al. Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer. J Clin Oncol. 2010;28:1124-1130.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1124-1130
-
-
Blackwell, K.L.1
Burstein, H.J.2
Storniolo, A.M.3
-
112
-
-
79952258750
-
First results of the NeoALTTO Trial (BIG 01-06/EGF 106903): A phase III, randomized, open label, neoadjuvant study of lapatinib, trastuzumab, and their combination plus paclitaxel in women with HER2-positive primary breast cancer
-
San Antonio, TX, abstract S3-3
-
Baselga J, Bradbury I, Eidtmann H, et al. First results of the NeoALTTO Trial (BIG 01-06/EGF 106903): A phase III, randomized, open label, neoadjuvant study of lapatinib, trastuzumab, and their combination plus paclitaxel in women with HER2-positive primary breast cancer. San Antonio Breast Cancer Symposium, 2010; San Antonio, TX, abstract S3-3.
-
(2010)
San Antonio Breast Cancer Symposium
-
-
Baselga, J.1
Bradbury, I.2
Eidtmann, H.3
-
113
-
-
84872666485
-
-
San Antonio, TX, abstract S3-2
-
Gianni L, Pienkowski T, Im Y-H, et al. Neoadjuvant pertuzumab (P) and trastuzumab (H): Antitumor and safety analysis of a randomized phase II study ('NeoSphere'). San Antonio Breast Cancer Symposium, 2010; San Antonio, TX, abstract S3-2.
-
(2010)
Neoadjuvant pertuzumab (P) and trastuzumab (H): Antitumor and safety analysis of a randomized phase II study ('NeoSphere'). San Antonio Breast Cancer Symposium
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.-H.3
-
114
-
-
80053526705
-
Adjuvant capecitabine and oxaliplatin for gastric cancer: Results of the phase III CLASSIC trial
-
abstract LBA4002
-
Bang Y, Kim YW, Yang H, et al. Adjuvant capecitabine and oxaliplatin for gastric cancer: Results of the phase III CLASSIC trial. J Clin Oncol. 2011;29. abstract LBA4002.
-
(2011)
J Clin Oncol.
, vol.29
-
-
Bang, Y.1
Kim, Y.W.2
Yang, H.3
|