-
1
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989;244:707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
2
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that over-expresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that over-expresses HER2. N Engl J Med 2001;344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
3
-
-
34548178720
-
Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: The trastuzumab and vinorelbine or taxane study
-
Burstein HJ, Keshaviah A, Baron AD et al. Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: The trastuzumab and vinorelbine or taxane study. Cancer 2007;110: 965-972.
-
(2007)
Cancer
, vol.110
, pp. 965-972
-
-
Burstein, H.J.1
Keshaviah, A.2
Baron, A.D.3
-
4
-
-
65649133875
-
Phase II trial of weekly do-cetaxel, vinorelbine, and trastuzumab in the first-line treatment of patients with HER2-positive metastatic breast cancer
-
Infante JR, Yardley DA, Burris HA 3rd et al. Phase II trial of weekly do-cetaxel, vinorelbine, and trastuzumab in the first-line treatment of patients with HER2-positive metastatic breast cancer. Clin Breast Cancer 2009;9: 23-28.
-
(2009)
Clin Breast Cancer
, vol.9
, pp. 23-28
-
-
Infante, J.R.1
Yardley, D.A.2
Burris, H.A.3
-
5
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: The M77001 study group
-
Marty M, Cognetti F, Maraninchi D et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: The M77001 study group. J Clin Oncol 2005;23:4265-4274.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
-
6
-
-
34548256855
-
Phase II study of capecitabine plus tras-tuzumab in human epidermal growth factor receptor 2 overexpressing met-astatic breast cancer pretreated with anthracyclines or taxanes
-
Schaller G, Fuchs I, Gonsch T et al. Phase II study of capecitabine plus tras-tuzumab in human epidermal growth factor receptor 2 overexpressing met-astatic breast cancer pretreated with anthracyclines or taxanes. J Clin Oncol 2007;25:3246-3250.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3246-3250
-
-
Schaller, G.1
Fuchs, I.2
Gonsch, T.3
-
7
-
-
32144448027
-
Reversibility of trastuzumab-related cardiotoxicity: New insights based on clinical course and response to medical treatment
-
Ewer MS, Vooletich MT, Durand JB et al. Reversibility of trastuzumab-related cardiotoxicity: New insights based on clinical course and response to medical treatment. J Clin Oncol 2005;23:7820-7826.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7820-7826
-
-
Ewer, M.S.1
Vooletich, M.T.2
Durand, J.B.3
-
8
-
-
77951058617
-
Trastuzumab-based therapy for patients with HER2-positive breast cancer: From early scientific development to foundation of care
-
Brufsky A. Trastuzumab-based therapy for patients with HER2-positive breast cancer: From early scientific development to foundation of care. Am J Clin Oncol 2010;33:186-195.
-
(2010)
Am J Clin Oncol
, vol.33
, pp. 186-195
-
-
Brufsky, A.1
-
9
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N EnglJMed 2005;353: 1673-1684.
-
(2005)
N EnglJMed
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
10
-
-
33845914783
-
2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomised controlled trial
-
Smith I, Procter M, Gelber RD et al. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomised controlled trial. Lancet 2007;369:29-36.
-
(2007)
Lancet
, vol.369
, pp. 29-36
-
-
Smith, I.1
Procter, M.2
Gelber, R.D.3
-
11
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastricorgastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastricorgastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet 2010;376:687-697.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
van Cutsem, E.2
Feyereislova, A.3
-
12
-
-
33846568336
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
-
Wolff AC, Hammond ME, Schwartz JN et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med 2007;131:18-43.
-
(2007)
Arch Pathol Lab Med
, vol.131
, pp. 18-43
-
-
Wolff, A.C.1
Hammond, M.E.2
Schwartz, J.N.3
-
13
-
-
33748555196
-
Chromogenic in situ hybridization to detect HER-2/neu gene amplification in histological and ThinPrep-processed breast cancer fine-needle aspirates: A sensitive and practical method in the trastuzumab era
-
Vocaturo A, Novelli F, Benevolo M et al. Chromogenic in situ hybridization to detect HER-2/neu gene amplification in histological and ThinPrep-processed breast cancer fine-needle aspirates: A sensitive and practical method in the trastuzumab era. The Oncologist 2006;11:878-886.
-
(2006)
The Oncologist
, vol.11
, pp. 878-886
-
-
Vocaturo, A.1
Novelli, F.2
Benevolo, M.3
-
14
-
-
67650988834
-
The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry
-
Damen CW, Speijer H, Hermens WT et al. The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry. Anal Biochem 2009;393:73-79.
-
(2009)
Anal Biochem
, vol.393
, pp. 73-79
-
-
Damen, C.W.1
Speijer, H.2
Hermens, W.T.3
-
15
-
-
41149154859
-
Treatment of breast cancer with trastuzumab during pregnancy
-
Pant S, Landon MB, Blumenfeld M et al. Treatment of breast cancer with trastuzumab during pregnancy. J Clin Oncol 2008;26:1567-1569.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1567-1569
-
-
Pant, S.1
Landon, M.B.2
Blumenfeld, M.3
-
16
-
-
33846017680
-
Anhydramnios associated with administration of trastuzumab and paclitaxel for metastatic breast cancer during pregnancy
-
Bader AA, Schlembach D, Tamussino KF et al. Anhydramnios associated with administration of trastuzumab and paclitaxel for metastatic breast cancer during pregnancy. Lancet Oncol 2007;8:79-81.
-
(2007)
Lancet Oncol
, vol.8
, pp. 79-81
-
-
Bader, A.A.1
Schlembach, D.2
Tamussino, K.F.3
-
17
-
-
26244444364
-
Genetic determinants of cancer drug efficacy and toxicity: Practical considerations and perspectives
-
Candelaria M, Taja-Chayeb L, Arce-Salinas C et al. Genetic determinants of cancer drug efficacy and toxicity: Practical considerations and perspectives. Anticancer Drugs 2005;16:923-933.
-
(2005)
Anticancer Drugs
, vol.16
, pp. 923-933
-
-
Candelaria, M.1
Taja-Chayeb, L.2
Arce-Salinas, C.3
-
18
-
-
34548179576
-
Role of the HER2 [Ile655Val] genetic polymorphism in tumorogenesis and in the risk of trastuzumab-related cardiotoxicity
-
Beauclair S, Formento P, Fischel JL et al. Role of the HER2 [Ile655Val] genetic polymorphism in tumorogenesis and in the risk of trastuzumab-related cardiotoxicity. Ann Oncol 2007;18:1335-1341.
-
(2007)
Ann Oncol
, vol.18
, pp. 1335-1341
-
-
Beauclair, S.1
Formento, P.2
Fischel, J.L.3
-
19
-
-
42949157368
-
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
-
Musolino A, Naldi N, Bortesi B et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol 2008;26:1789-1796.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1789-1796
-
-
Musolino, A.1
Naldi, N.2
Bortesi, B.3
-
20
-
-
34548531901
-
Trastuzumab-associated cardiac adverse effects in the Herceptin Adjuvant trial
-
Suter TM, Procter M, van Veldhuisen DJ et al. Trastuzumab-associated cardiac adverse effects in the Herceptin Adjuvant trial. J Clin Oncol 2007;25: 3859-3865.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3859-3865
-
-
Suter, T.M.1
Procter, M.2
van Veldhuisen, D.J.3
-
21
-
-
29744442709
-
Assessmentofcardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31
-
Tan-Chiu E, Yothers G, Romond E et al. Assessmentofcardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31. J Clin Oncol 2005;23:7811-7819.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7811-7819
-
-
Tan-Chiu, E.1
Yothers, G.2
Romond, E.3
-
22
-
-
38549134656
-
Cardiotoxicity and incidence of brain metastases after adjuvant trastuzumab for early breast cancer: The dark side of the moon? A meta-analysis of the randomized trials
-
Bria E, Cuppone F, Fornier M et al. Cardiotoxicity and incidence of brain metastases after adjuvant trastuzumab for early breast cancer: The dark side of the moon? A meta-analysis of the randomized trials. Breast Cancer Res Treat 2008;109:231-239.
-
(2008)
Breast Cancer Res Treat
, vol.109
, pp. 231-239
-
-
Bria, E.1
Cuppone, F.2
Fornier, M.3
-
23
-
-
77955284952
-
Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosph-amide followed by trastuzumab adjuvant therapy: A combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials
-
Russell SD, Blackwell KL, Lawrence J et al. Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosph-amide followed by trastuzumab adjuvant therapy: A combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials. J Clin Oncol 2010;28:3416-3421.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3416-3421
-
-
Russell, S.D.1
Blackwell, K.L.2
Lawrence, J.3
-
24
-
-
77955284228
-
Longer-term assessment of tras-tuzumab-related cardiac adverse events in the Herceptin Adjuvant (HERA) trial
-
Procter M, Suter TM, deAzambuja E et al. Longer-term assessment of tras-tuzumab-related cardiac adverse events in the Herceptin Adjuvant (HERA) trial. J Clin Oncol 2010;28:3422-3428.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3422-3428
-
-
Procter, M.1
Suter, T.M.2
Deazambuja, E.3
-
25
-
-
33344478381
-
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
-
Joensuu H, Kellokumpu-Lehtinen PL, Bono P et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 2006;354:809-820.
-
(2006)
N Engl J Med
, vol.354
, pp. 809-820
-
-
Joensuu, H.1
Kellokumpu-Lehtinen, P.L.2
Bono, P.3
-
26
-
-
77955296163
-
Trastuzumab-related cardiotoxicity following an-thracycline-based adjuvant chemotherapy: How worried should we be?
-
Morris PG, Hudis CA. Trastuzumab-related cardiotoxicity following an-thracycline-based adjuvant chemotherapy: How worried should we be? J Clin Oncol 2010;28:3407-3410.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3407-3410
-
-
Morris, P.G.1
Hudis, C.A.2
-
27
-
-
68949121146
-
Trastuzumab mediated cardio-toxicity in the setting of adjuvant chemotherapy for breast cancer: A retrospective study
-
Wadhwa D, Fallah-Rad N, Grenier D et al. Trastuzumab mediated cardio-toxicity in the setting of adjuvant chemotherapy for breast cancer: A retrospective study. Breast Cancer Res Treat 2009;117:357-364.
-
(2009)
Breast Cancer Res Treat
, vol.117
, pp. 357-364
-
-
Wadhwa, D.1
Fallah-Rad, N.2
Grenier, D.3
-
28
-
-
33748642331
-
Long-term cardiac tolerability of trastuzumabinmetastatic breast cancer: The M.D. Anderson Cancer Center experience
-
Guarneri V, Lenihan DJ, Valero V et al. Long-term cardiac tolerability of trastuzumabinmetastatic breast cancer: The M.D. Anderson Cancer Center experience. J Clin Oncol 2006;24:4107-4115.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4107-4115
-
-
Guarneri, V.1
Lenihan, D.J.2
Valero, V.3
-
29
-
-
0036344533
-
Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors
-
Camenisch TD, Schroeder JA, Bradley J et al. Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors. Nat Med 2002;8:850-855.
-
(2002)
Nat Med
, vol.8
, pp. 850-855
-
-
Camenisch, T.D.1
Schroeder, J.A.2
Bradley, J.3
-
30
-
-
0028884413
-
Requirement for neuregulin receptor erbB2 in neural and cardiac development
-
Lee KF, Simon H, Chen H et al. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995;378:394-398.
-
(1995)
Nature
, vol.378
, pp. 394-398
-
-
Lee, K.F.1
Simon, H.2
Chen, H.3
-
31
-
-
0037172982
-
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
-
Ozcelik C, Erdmann B, Pilz B et al. Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci U S A 2002;99:8880-8885.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8880-8885
-
-
Ozcelik, C.1
Erdmann, B.2
Pilz, B.3
-
32
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
Crone SA, Zhao YY, Fan L et al. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 2002;8:459-465.
-
(2002)
Nat Med
, vol.8
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.Y.2
Fan, L.3
-
33
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995;378:386-390.
-
(1995)
Nature
, vol.378
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
34
-
-
0036289525
-
Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart
-
Uray IP, Connelly JH, Thomàzy V et al. Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart. J Heart Lung Transplant 2002;21:771-782.
-
(2002)
J Heart Lung Transplant
, vol.21
, pp. 771-782
-
-
Uray, I.P.1
Connelly, J.H.2
Thomàzy, V.3
-
35
-
-
0345688767
-
Analysis of HER2 and HER4 in human myocardium to clarify the cardiotoxicity of trastuzumab (Herceptin)
-
Fuchs IB, Landt S, Bueler H et al. Analysis of HER2 and HER4 in human myocardium to clarify the cardiotoxicity of trastuzumab (Herceptin). Breast Cancer Res Treat 2003;82:23-28.
-
(2003)
Breast Cancer Res Treat
, vol.82
, pp. 23-28
-
-
Fuchs, I.B.1
Landt, S.2
Bueler, H.3
-
36
-
-
33744831505
-
Indium-111-labeled tras-tuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
-
Perik PJ, Lub-De Hooge MN, Gietema JA et al. Indium-111-labeled tras-tuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. J Clin Oncol 2006;24:2276-2282.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2276-2282
-
-
Perik, P.J.1
de hooge, M.N.L.2
Gietema, J.A.3
-
37
-
-
77957567061
-
Trastuzumab-induced cardiotox-icity: Clinical and prognostic implications of troponin I evaluation
-
Cardinale D, Colombo A, Torrisi R et al. Trastuzumab-induced cardiotox-icity: Clinical and prognostic implications of troponin I evaluation. J Clin Oncol 2010;28:3910-3916.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3910-3916
-
-
Cardinale, D.1
Colombo, A.2
Torrisi, R.3
-
38
-
-
0034755872
-
Retrospective analysis of the safety of Herceptin immuno-therapy in metastatic breast cancer
-
Cook-Bruns N. Retrospective analysis of the safety of Herceptin immuno-therapy in metastatic breast cancer. Oncology 2001;61(suppl 2):58-66.
-
(2001)
Oncology
, vol.61
, Issue.SUPPL. 2
, pp. 58-66
-
-
Cook-Bruns, N.1
-
39
-
-
9244219598
-
Breast cancer-loss of PTEN predicts resistance to treatment
-
Pandolfi PP. Breast cancer-loss of PTEN predicts resistance to treatment. N Engl J Med 2004;351:2337-2338.
-
(2004)
N Engl J Med
, vol.351
, pp. 2337-2338
-
-
Pandolfi, P.P.1
-
40
-
-
35148854641
-
PI3 kinase activation and response to trastuzumab therapy: What's neu with Herceptin resistance
-
Park BH, Davidson NE. PI3 kinase activation and response to trastuzumab therapy: What's neu with Herceptin resistance? Cancer Cell 2007;12:297-299.
-
(2007)
Cancer Cell
, vol.12
, pp. 297-299
-
-
Park, B.H.1
Davidson, N.E.2
-
41
-
-
33947246109
-
Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer
-
Harris LN, You F, Schnitt SJ et al. Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer. Clin Cancer Res 2007;13:1198-1207.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1198-1207
-
-
Harris, L.N.1
You, F.2
Schnitt, S.J.3
-
42
-
-
34547854801
-
The oncogene HER2: Its signaling and transforming functions and its role in human cancer pathogenesis
-
Moasser MM. The oncogene HER2: Its signaling and transforming functions and its role in human cancer pathogenesis. Oncogene 2007;26:6469-6487.
-
(2007)
Oncogene
, vol.26
, pp. 6469-6487
-
-
Moasser, M.M.1
-
43
-
-
65349110371
-
Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A German Breast Group 26/Breast International Group 03-05 study
-
von Minckwitz G, du Bois A, Schmidt M et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A German Breast Group 26/Breast International Group 03-05 study. J Clin Oncol 2009;27:1999-2006.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1999-2006
-
-
von Minckwitz, G.1
du Bois, A.2
Schmidt, M.3
-
44
-
-
61649118623
-
Single-agent lapatinib for HER2-overexpressing advanced ormetastatic breast cancer that progressed on first-or second-line trastuzumab-containing regimens
-
Blackwell KL, Pegram MD, Tan-Chiu E et al. Single-agent lapatinib for HER2-overexpressing advanced ormetastatic breast cancer that progressed on first-or second-line trastuzumab-containing regimens. Ann Oncol 2009; 20:1026-1031.
-
(2009)
Ann Oncol
, vol.20
, pp. 1026-1031
-
-
Blackwell, K.L.1
Pegram, M.D.2
Tan-Chiu, E.3
-
45
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
Cameron D, Casey M, Press M et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses. Breast Cancer Res Treat 2008;112:533-543.
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 533-543
-
-
Cameron, D.1
Casey, M.2
Press, M.3
-
46
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
Geyer CE, Forster J, Lindquist D et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 2006;355:2733-2743.
-
(2006)
N Engl J Med
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
47
-
-
77949884661
-
Randomized study of lapa-tinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer
-
Blackwell KL, Burstein HJ, Storniolo AM et al. Randomized study of lapa-tinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer. J Clin Oncol 2010;28:1124-1130.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1124-1130
-
-
Blackwell, K.L.1
Burstein, H.J.2
Storniolo, A.M.3
-
48
-
-
77950497981
-
Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer
-
Burstein HJ, Sun Y, Dirix LY et al. Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer. J Clin Oncol 2010;28:1301-1307.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1301-1307
-
-
Burstein, H.J.1
Sun, Y.2
Dirix, L.Y.3
-
49
-
-
77954031486
-
Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer
-
Krop IE, Beeram M, Modi S et al. Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer. J Clin Oncol 2010;28:2698-2704.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2698-2704
-
-
Krop, I.E.1
Beeram, M.2
Modi, S.3
-
50
-
-
77949903478
-
Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastu-zumab therapy
-
Baselga J, Gelmon KA, Verma S et al. Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastu-zumab therapy. J Clin Oncol 2010;28:1138-1144.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1138-1144
-
-
Baselga, J.1
Gelmon, K.A.2
Verma, S.3
-
51
-
-
73949105921
-
Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: Results from the randomized phase III TAnDEM study
-
Kaufman B, Mackey JR, Clemens MR et al. Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: Results from the randomized phase III TAnDEM study. J Clin Oncol 2009;27:5529-5537.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5529-5537
-
-
Kaufman, B.1
Mackey, J.R.2
Clemens, M.R.3
-
52
-
-
33745530224
-
Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer
-
Robert N, Leyland-Jones B, Asmar L et al. Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer. J Clin Oncol 2006;24:2786-2792.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2786-2792
-
-
Robert, N.1
Leyland-Jones, B.2
Asmar, L.3
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