Long-term outcome of hepatitis C infection after liver transplantation

New England Journal of Medicine

Volumn 334, Issue 13, 1996, Pages 815-820

  Gane, Edward J ^a   Portmann, Bernard G ^a   Naoumov, Nikolai V ^a   Smith, Heather M ^a   Underhill, James A ^a   Donaldson, Peter T ^a   Maertens, Geert ^b   Willlams, Roger ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b INNOGENETICS   (Belgium)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; FEMALE; FOLLOW UP; GRAFT REJECTION; GRAFT SURVIVAL; HEPATITIS C; HLA MATCHING; HUMAN; LIVER FAILURE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; RECURRENT INFECTION; TREATMENT OUTCOME;

ADULT; AGED; BIOPSY; CHRONIC DISEASE; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; GRAFT SURVIVAL; HEPACIVIRUS; HEPATITIS C; HISTOCOMPATIBILITY TESTING; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0029914375     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199603283341302     Document Type: Article

References (45)

1. Wright TL, Donegan E, Hsu HH, et al. Recurrent and acquired hepatitis C viral infection in liver transplant recipients. Gastroenterology 1992;103: 317-22.
2. Konig V, Bauditz J, Lobeck H, et al. Hepatitis C virus reinfection in allografts after orthotopic liver transplantation. Hepatology 1992;16.1137-43.
3. Ascher NL, Lake JR, Emond J, Roberts J Liver transplantation for hepatitis C virus-related cirrhosis. Hepatology 1994,20:24S-27S.
4. Shah G, Demetris AJ, Gavaler JS, et al. Incidence, prevalence, and clinical course of hepatitis C following liver transplantation. Gastroenterology 1992;103:323-9.
5. Chazouilleres O, Kim M, Combs C, et al. Quantitation of hepatitis C virus RNA in liver transplant recipients. Gastroenterology 1994;106 994-9.
6. Weinstein JS, Poterucha JJ, Rakela J, Krom RAF, Wiesner RH. Long-term outcome of hepatitis C (HCV) infected liver transplant (OLT) recipients. Hepatology 1994,20:Suppl:133A. abstract.
7. Casavilla A, Mateo R, Rakela J, et al. Impact of hepatitis C virus (HCV) infection on survival following primary liver transplantation (OLTX) under FK506 Hepatology 1994;20:Suppl 133A. abstract
8. Feray C, Gigou M, Samuel D, et al. The course of hepatitis C infection after liver transplantation. Hepatology 1994;20:1137-43.
9. Seeff LB, Buskell-Bales Z, Wright EC, et al. Long-term mortality after transfusion-associated non-A, non-B hepatitis N Engl J Med 1992;327:1906-11.
10. Alter MJ, Margolis HS, Krawczynski K, et al. The natural history of community-acquired hepatitis C in the United States N Engl J Med 1992;327. 1899-905
11. Gretch D, Wile M, Gaur L, et al. Donor-recipient match at the HLA-DQB locus is associated with recrudescence of chronic hepatitis following liver transplantation for end stage hepatitis C Hepatology 1993;18 Suppl:108A. abstract.
12. Feray C, Gigou M, Samuel D, et al. Influence of the genotypes of hepatitis C virus on the severity of recurrent liver disease after liver transplantation. Gastroenterology 1995;108:1089-96.
13. Zhou S, Kim M, Ferrell L, Wright TL HCV genotyping of liver transplant (OLT) recipientsrelation to viremia and histology. Hepatology 1994;20: Suppl:134A. abstract
14. Gane E, Naoumov N, Qian K, et al A longitudinal analysis of hepatitis C virus replication following liver transplantation. Gastroenterology 1996; 110:167-77.
15. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994,19: 1513-20.
16. Tilston P, Morris DJ, Klapper PE, Corbitt G. Commercial assay for hepatitis C virus RNA. Lancet 1994;344:201-2.
17. Izopet J, Bogard M, Costes J, et al. Multicenter evaluation of analytical performances of the Amplicor HCV RNA qualitative assay. Hepatology 1994; 20:Suppl:241A. abstract.
18. van Doom LJ, Kleter B, Stuyver L, et al. Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles. J Hepatol 1994;21:122-9
19. Terasaki P, McClelland JD, Park MS, McCurdy B. Microdroplet assay of human serum cytotoxins. In: Ray JG, Hare DB, Pederson PD, Kayhoe DE, eds. Manual of tissue typing techniques Bethesda, Md : National Institutes of Health, 1974:67-74. (DHEW publication no. (NIH) 75-548)
20. Donaldson P, Underbill J, Doherty D, et al. Influence of human leukocyte antigen matching on liver allograft survival and rejection: "the dualistic effect." Hepatology 1993;17:1008-15.
21. Cox DR, Oakes D. Analysis of survival data. London. Chapman & Hall, 1984
22. Armitage P, Berry G. Statistical methods in medical research. 3rd ed Oxford, England Blackwell Science, 1994.
23. Lim HL, Lau GK, Davis GL, Dolson DJ, Lau JY. Cholestatic hepatitis leading to hepatic failure in a patient with organ-transmitted hepatitis C virus infection Gastroenterology 1994;106:248-51.
24. Schluger LK, Min A, Wolf DC, et al. Severe recurrent cholestatic hepatitis C following orthotopic liver transplantation. Gastroenterology 1994;106: Suppl:A978 abstract.
25. Davies SE, Portmann BC, O'Grady JG, et al. Hepatic histological findings after transplantation for chronic hepatitis B virus infection, including a unique pattern of fibrosing cholestatic hepatitis Hepatology 1991;13:150-7.
26. DiBisceghe AM, Goodman ZD, Ishak KG, Hoofnagle JH, Melpolder JJ, Alter HJ Long-term clinical and histopathological follow-up of chronic posttransfusion hepatitis. Hepatology 1991;14:969-74.
27. Mondelli M. Alberti A, Tremolada F, Williams R, Eddleston AL, Realdi G. In-vitro cell-mediated cytotoxicity for autologous liver cells in chronic non-A, non-B hepatitis. Clin Exp Immunol 1986;63:147-55.
28. Koziel MJ, Dudley D, Afdhal N, et al. Hepatitis C virus (HCV) specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV. J Virol 1993;67:7522-32.
29. Botarelli P, Brunetto MR, Minutello MA, et al. T-lymphocyte response to hepatitis C virus in different clinical courses of infection. Gastroenterology 1993;104.580-7.
30. Ferrari C, Valli A, Galati L, et al. T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections. Hepatology 1994;19:286-95.
31. Dusheiko G, Schmilovilz-Weiss H, Brown D, et al. Hepatitis C virus genotypes: an investigation of type-specific differences in geographic origin and disease. Hepatology 1994;19.13-8.
32. Qu D, Li JS, Vitvitski L, et al Hepatitis C virus genotypes in France: comparison of clinical features of patients infected with HCV type I and type II. J Hepatol 1994;21:70-5.
33. Pozzato G, Kaneko S, Moretti M, et al. Different genotypes of hepatitis C virus are associated with different severity of chronic liver disease. J Med Virol 1994;43:291-6.
34. Yuki N, Hayashi N, Kasahara A, et al. Pretreatment viral load and response to prolonged interferon-alpha course for chronic hepatitis C. J Hepatol 1995;22.457-63.
35. Poynard T, Bedossa P, Chevallier M, et al. A comparison of three Interferon alfa-2b regimens for the long-term treatment of chronic non-A, non-B hepatitis. N Engl J Med 1995;332.1457-62.
36. Ballardini G, Groff P, Pontisso P, et al. Hepatitis C virus (HCV) genotype, tissue HCV antigens, hepatocellular expression of HLA-A,B,C, and intercellular adhesion-1 molecules: clues to pathogenesis of hepatocellular dam age and response to interferon treatment in patients with chronic hepatitis C. J Clin Invest 1995;95:2067-75.
37. Nagayama R, Tsuda F, Okamoto H, et al. Genotype dependence of hepatitis C virus antibodies detectable by the first-generation enzyme-linked immunosorbent assay with C100-3 protein. J Clin Invest 1993,92:1529-33
38. Tanaka T, Tsukiyama-Kohara K, Yamaguchi K, et al Significance of specific antibody assay for genotyping of hepatitis C virus. Hepatology 1994;19 1347-53.
39. Willems M, Sheng L, Roskams T, et al. Hepatitis C virus and its genotypes in patients suffering from chronic hepatitis C with or without a cryoglobulinemia-related syndrome. J Med Virol 1994.44:266-71.
40. Magrin S, Craxi A, Fabiano C, et al. Hepatitis C viremia in chronic liver disease: relationship to interferon-α or corticosteroid treatment Hepatology 1994;19:273-9
41. McHutchison JG, Wilkes LB, Pockros PJ, et al. Pulse corticosteroid therapy increases viremia (HCV RNA) in patients with chronic HCV infection. Hepatology 1993;18:Suppl:87A, abstract.
42. Sheiner PA, Schwartz ME, Mor E, et al. Severe or multiple rejection episodes are associated with early recurrence of hepatitis C after orthotopic liver transplantation. Hepatology 1995;21:30-4.
43. The U.S Multicenter FK506 Liver Study Group. A comparison of tacrolimus (FK 506) and cyclosporine for immunosappression in liver transplantation. N Engl J Med 1994;331:1110-5.
44. European FK506 Multicentre Liver Study Group. Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejection Lancet 1994;344:423-8.
45. Rosen HR, Martin P, Shackleton CR, Farmer DA, Holt C, Busuttil RW. OKT3 use associated with diminished graft and patient survival in patients transplanted for chronic hepatitis C. Hepatology 1995;22:Suppl. 132A. abstract.