Trastuzumab anti-tumor efficacy in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Wu, Xianhua ^a   Zhang, Jingchuan ^b   Zhen, Ruheng ^a   Lv, Jing ^b   Zheng, Li ^b   Su, Xinying ^b   Zhu, Guanshan ^b   Gavine, Paul R ^b   Xu, Songtao ^a   Lu, Shaohua ^a   Hou, Jun ^a   Liu, Yalan ^a   Xu, Chen ^a   Tan, Yunshan ^a   Xie, Liang ^b   Yin, Xiaolu ^b   He, Deming ^a   Ji, Qunsheng ^b   Hou, Yingyong ^a   Ge, Di ^a  

^a FUDAN UNIVERSITY   (China)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Esophageal carcinoma; HER 2; Herceptin; PIK3CA mutation; Xenograft model

Indexed keywords

AZD 5363; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; TRASTUZUMAB; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; B RAF GENE; CANCER REGRESSION; CONTROLLED STUDY; DRUG EFFICACY; EGFR GENE; ENZYME ACTIVATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE AMPLIFICATION; GENE DOSAGE; GENE MUTATION; GENETIC SCREENING; HER 2 GENE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; K RAS GENE; MOUSE; NONHUMAN; ONCOGENE; PIK3 GENE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; DISEASE MODELS, ANIMAL; DNA PRIMERS; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICE, NUDE; MICE, SCID; POLYMERASE CHAIN REACTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84865463264     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-180     Document Type: Article

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