PIK3CA Mutation Status in Japanese Esophageal Squamous Cell Carcinoma

Journal of Surgical Research

Volumn 145, Issue 2, 2008, Pages 320-326

  Mori, Ryota ^a   Ishiguro, Hideyuki ^a   Kimura, Masahiro ^a   Mitsui, Akira ^a   Sasaki, Hidefumi ^a   Tomoda, Keisuke ^a   Mori, Yoichiro ^a   Ogawa, Ryo ^a   Katada, Takeyasu ^a   Kawano, Osamu ^a   Harada, Koshiro ^a   Fujii, Yoshitaka ^a   Kuwabara, Yoshiyuki ^a  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

esophageal cancer; mutational analysis; PI3K inhibitor (LY294002); PIK3CA

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; PHOSPHATIDYLINOSITOL 3 KINASE;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER SURGERY; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; GENE MUTATION; GENE SEQUENCE; HETEROZYGOSITY; HUMAN; HUMAN CELL; JAPAN; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL LINE, TUMOR; CHROMONES; DNA MUTATIONAL ANALYSIS; ENZYME INHIBITORS; ESOPHAGEAL NEOPLASMS; EXONS; FEMALE; HUMANS; MALE; MIDDLE AGED; MORPHOLINES; MUTATION, MISSENSE;

EID: 40149101093     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2007.03.044     Document Type: Article

References (30)

1. Karakas B., Bachman K.E., and Park B.H. Mutation of the PIK3CA oncogene in human cancers. Br J Cancer 94 (2006) 455
2. Samuels Y., Wang Z., Bardelli A., et al. High frequency of mutations of the PIK3CA gene in human cancers. Science (2004) 304
3. Bachman K.E., Argani P., Samuels Y., et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther 3 (2004) 772
4. Lee J.W., Soung Y.H., Kim S.Y., et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 24 (2005) 1477
5. Campbell I.G., Russell S.E., Choong D.Y., et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 64 (2004) 7678
6. Broderick D.K., Di C., Parrett T.J., et al. Mutations of PIK3CA gene in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. Cancer Res 64 (2004) 5048
7. Wang Y., Helland A., Holm R., et al. PIK3CA mutation in advanced ovarian carcinomas. Hum Mutant 25 (2005) 322
8. Kang S., Bader A.G., and Vogt P.K. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci USA 102 (2005) 802
9. Phillips W.A., Russell S.E., Ciavarell M.L., et al. Mutation analysis of PIK3CA and PIK3CB in esophageal cancer and Barrett's esophagus. Int J Cancer 118 (2006) 2644
10. Wittwer C.T., Herrmann M.G., Moss A.A., et al. Continuous fluorescence monitoring of rapid cycle DNA amplification. Biotechniques 22 (1997) 130
11. Wittwer C.T., Reed G.B., and Ririe K.M. Rapid cycle amplification. In: Mullis K.B., Ferre F., and Gibbs R.A. (Eds). The Polymerase Chain Reaction (1994), Birkhauser, Boston 174
12. Pals G., Pindolia K., and Worsham M.J. A rapid and sensitive approach to mutation detection using real-time polymerase chain reaction and melting curve analyses, using BRCA1 as an example. Mol Diagn 4 (1999) 241
13. Wittwer C.T., Ririe M., Andrew V., et al. The LightCycler: A microvolume multi-sample fluorimeter with rapid temperature control. Biotechniques 22 (1997) 176
14. Whyte D.B., and Holbeck S.L. Correlation of PIK3CA mutations with gene expression and drug sensitivity in NCI-60 cell lines. Biochem Biophys Res Commun 340 (2006) 469
15. Qiu W., Schönleben F., Li X., et al. PIK3CA mutations in head and neck squamous cell carcinoma. Clin Cancer Res 12 (2006) 1441
16. Endo K., Konishi A., Sasaki H., et al. Epidermal growth factor receptor gene mutation in non-small cell lung cancer using highly sensitive and fast TaqMan PCR assay. Lung Cancer 50 (2005) 375
17. Sasaki H., Endo K., Konishi A., et al. EGFR mutation status in Japanese lung cancer patients: Genotyping analysis using LightCycler. Clin Cancer Res 11 (2005) 2924
18. Pals G., Young C., Mao H.S., et al. Detection of a single base substitution in a single cell using the LightCycler. J Biochem Biophys Methods 47 (2001) 121
19. Heid C.A., Stevens J., and William P.M. Real time quantitative PCR. Genome Res 6 (1996) 986
20. Li V.S., Wong C.W., Chan T.L., et al. Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer 5 (2005) 29
21. Ikenoue T., Kanai F., Hikiba Y., et al. Functional analysis of PIK3CA gene mutations in human colorectal cancer. Cancer Res 65 (2005) 4562
22. Kang S., Bader A.G., and Vogt P.K. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci USA 102 (2005) 802
23. Samuel Y., Dia Jr. L.A., and Schmidt-Kittler N. Mutant PIK3CA promote cell growth and invasion of human cancer cells. Cancer Cell 7 (2005) 561
24. Bader A.G., Kang S., and Vogt P.K. Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci USA 103 (2006) 1475
25. Sugita M., Tanaka N., Davidson S., et al. Molecular definition of a small amplification domain within 3q26 in tumors of cervix, ovary, and lung. Cancer Genet Cytogenet 117 (2000) 9
26. Chujo M., Noguchi M., Miura T., et al. Comparative genomic hybridization analysis detected frequent overrepresentation of chromosome 3q in squamous cell carcinoma of the lung. Lung Cancer 38 (2002) 23
27. Racz A., Brass N., Heckel D., et al. Expression analysis of genes at 3q26-q27 involved in frequent amplification in squamous cell lung carcinoma. Eur J Cancer 35 (1999) 641
28. Limin H., Charles Z., et al. In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002). Clin Cancer Res 6 (2000) 880
29. Downward J. Ras signaling and apoptosis. Curr Opin Genet Dev 1 (1988) 49
30. Foukas L.C., Claret M., Pearce W., et al. Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature 441 (2006) 366-370