-
1
-
-
33646568784
-
Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
-
Kamangar F, Dores G M, Anderson W F. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006; 24: 2137-50.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2137-2150
-
-
Kamangar, F.1
Dores, G.M.2
Anderson, W.F.3
-
2
-
-
0032722946
-
Comprehensive prevention and treatment for esophageal cancer
-
Lu S, Lin P, Wang G, Luo X, Wu M. Comprehensive prevention and treatment for esophageal cancer. Chin Med J (Engl) 1999; 112: 918-23.
-
(1999)
Chin Med J (Engl)
, vol.112
, pp. 918-923
-
-
Lu, S.1
Lin, P.2
Wang, G.3
Luo, X.4
Wu, M.5
-
3
-
-
0037109014
-
ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
-
Wakeling A E, Guy S P, Woodburn J R etal. ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 2002; 62: 5749-54.
-
(2002)
Cancer Res
, vol.62
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
-
4
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
-
Fukuoka M, Yano S, Giaccone G etal. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 2003; 21: 2237-46.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
-
5
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial
-
Kris M G, Natale R B, Herbst R S etal. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003; 290: 2149-58.
-
(2003)
JAMA
, vol.290
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
-
6
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T J, Bell D W, Sordella R etal. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
7
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J G, Janne P A, Lee J C etal. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
8
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M etal. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004; 101: 13306-11.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
9
-
-
21044445279
-
Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer
-
Chou T Y, Chiu C H, Li L H etal. Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer. Clin Cancer Res 2005; 11: 3750-7.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3750-3757
-
-
Chou, T.Y.1
Chiu, C.H.2
Li, L.H.3
-
10
-
-
20244389188
-
Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib
-
Han S W, Kim T Y, Hwang P G etal. Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. J Clin Oncol 2005; 23: 2493-501.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2493-2501
-
-
Han, S.W.1
Kim, T.Y.2
Hwang, P.G.3
-
11
-
-
34548182258
-
Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features
-
Finberg K E, Sequist L V, Joshi V A etal. Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features. J Mol Diagn 2007; 9: 320-6.
-
(2007)
J Mol Diagn
, vol.9
, pp. 320-326
-
-
Finberg, K.E.1
Sequist, L.V.2
Joshi, V.A.3
-
12
-
-
33846220461
-
Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas
-
Kwak E L, Jankowski J, Thayer S P etal. Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas. Clin Cancer Res 2006; 12 (Pt 1): 4283-7.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.PART 1
, pp. 4283-4287
-
-
Kwak, E.L.1
Jankowski, J.2
Thayer, S.P.3
-
13
-
-
33846337182
-
Identification of EGFR mutations in esophageal cancer
-
Sudo T, Mimori K, Nagahara H etal. Identification of EGFR mutations in esophageal cancer. Eur J Surg Oncol 2007; 33: 44-8.
-
(2007)
Eur J Surg Oncol
, vol.33
, pp. 44-48
-
-
Sudo, T.1
Mimori, K.2
Nagahara, H.3
-
14
-
-
33646706077
-
Gefitinib-sensitizing mutations in esophageal carcinoma
-
Guo M, Liu S, Lu F. Gefitinib-sensitizing mutations in esophageal carcinoma. N Engl J Med 2006; 354: 2193-4.
-
(2006)
N Engl J Med
, vol.354
, pp. 2193-2194
-
-
Guo, M.1
Liu, S.2
Lu, F.3
-
15
-
-
31844432805
-
EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus
-
Hanawa M, Suzuki S, Dobashi Y etal. EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus. Int J Cancer 2006; 118: 1173-80.
-
(2006)
Int J Cancer
, vol.118
, pp. 1173-1180
-
-
Hanawa, M.1
Suzuki, S.2
Dobashi, Y.3
-
16
-
-
33645734242
-
Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients
-
Janmaat M L, Gallegos-Ruiz M I, Rodriguez J A etal. Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients. J Clin Oncol 2006; 24: 1612-19.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1612-1619
-
-
Janmaat, M.L.1
Gallegos-Ruiz, M.I.2
Rodriguez, J.A.3
-
17
-
-
33846218549
-
Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas
-
Puhringer-Oppermann F A, Stein H J, Sarbia M. Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas. Dis Esophagus 2007; 20: 9-11.
-
(2007)
Dis Esophagus
, vol.20
, pp. 9-11
-
-
Puhringer-Oppermann, F.A.1
Stein, H.J.2
Sarbia, M.3
-
18
-
-
0025303624
-
Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products
-
Meltzer S J, Mane S M, Wood P K etal. Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products. Cancer Res 1990; 50: 3627-30.
-
(1990)
Cancer Res
, vol.50
, pp. 3627-3630
-
-
Meltzer, S.J.1
Mane, S.M.2
Wood, P.K.3
-
19
-
-
0030843339
-
ras mutation and expression of the ras-regulated genes osteopontin and cathepsin L in human esophageal cancer
-
Casson A G, Wilson S M, McCart J A etal. ras mutation and expression of the ras-regulated genes osteopontin and cathepsin L in human esophageal cancer. Int J Cancer 1997; 72: 739-45.
-
(1997)
Int J Cancer
, vol.72
, pp. 739-745
-
-
Casson, A.G.1
Wilson, S.M.2
McCart, J.A.3
-
20
-
-
0029792591
-
K-ras point mutations are rare events in premalignant forms of Barrett's oesophagus
-
Trautmann B, Wittekind C, Strobel D etal. K-ras point mutations are rare events in premalignant forms of Barrett's oesophagus. Eur J Gastroenterol Hepatol 1996; 8: 799-804.
-
(1996)
Eur J Gastroenterol Hepatol
, vol.8
, pp. 799-804
-
-
Trautmann, B.1
Wittekind, C.2
Strobel, D.3
-
21
-
-
10744233317
-
Mutations of BRAF and KRAS2 in the development of Barrett's adenocarcinoma
-
Sommerer F, Vieth M, Markwarth A etal. Mutations of BRAF and KRAS2 in the development of Barrett's adenocarcinoma. Oncogene 2004; 23: 554-8.
-
(2004)
Oncogene
, vol.23
, pp. 554-558
-
-
Sommerer, F.1
Vieth, M.2
Markwarth, A.3
-
22
-
-
0034230732
-
K-ras codon 12 mutations in Barrett's oesophagus and adenocarcinomas of the oesophagus and oesophagogastric junction
-
Lord R V, O'Grady R, Sheehan C, Field A F, Ward R L. K-ras codon 12 mutations in Barrett's oesophagus and adenocarcinomas of the oesophagus and oesophagogastric junction. J Gastroenterol Hepatol 2000; 15: 730-6.
-
(2000)
J Gastroenterol Hepatol
, vol.15
, pp. 730-736
-
-
Lord, R.V.1
O'Grady, R.2
Sheehan, C.3
Field, A.F.4
Ward, R.L.5
-
23
-
-
0034076511
-
Activation of c-K-ras mutations in human gastrointestinal tumors
-
Arber N, Shapira I, Ratan J etal. Activation of c-K-ras mutations in human gastrointestinal tumors. Gastroenterology 2000; 118: 1045-50.
-
(2000)
Gastroenterology
, vol.118
, pp. 1045-1050
-
-
Arber, N.1
Shapira, I.2
Ratan, J.3
-
24
-
-
58549098525
-
K-ras mutation, HPV infection and smoking or alcohol abuse positively correlate with esophageal squamous carcinoma
-
Lyronis I D, Baritaki S, Bizakis I, Krambovitis E, Spandidos j D A. K-ras mutation, HPV infection and smoking or alcohol abuse positively correlate with esophageal squamous carcinoma. Pathol Oncol Res 2008; 14: 267-73.
-
(2008)
Pathol Oncol Res
, vol.14
, pp. 267-273
-
-
Lyronis, I.D.1
Baritaki, S.2
Bizakis, I.3
Krambovitis, E.4
Spandidos, D.A.5
-
25
-
-
0025118675
-
No evidence for point mutations in codons 12, 13, and 61 of the ras gene in a high-incidence area for esophageal and gastric cancers
-
Victor T, Du Toit R, Jordaan A M, Bester A J, van Helden P D. No evidence for point mutations in codons 12, 13, and 61 of the ras gene in a high-incidence area for esophageal and gastric cancers. Cancer Res 1990; 50: 4911-14.
-
(1990)
Cancer Res
, vol.50
, pp. 4911-4914
-
-
Victor, T.1
Du Toit, R.2
Jordaan, A.M.3
Bester, A.J.4
van Helden, P.D.5
-
26
-
-
21744460198
-
Antitumor effect of gefitinib ('Iressa') on esophageal squamous cell carcinoma cell lines in vitro and in vivo
-
Hara F, Aoe M, Doihara H etal. Antitumor effect of gefitinib ('Iressa') on esophageal squamous cell carcinoma cell lines in vitro and in vivo. Cancer Lett 2005; 226: 37-47.
-
(2005)
Cancer Lett
, vol.226
, pp. 37-47
-
-
Hara, F.1
Aoe, M.2
Doihara, H.3
-
27
-
-
33750618860
-
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
-
Dragovich T, McCoy S, Fenoglio-Preiser C M etal. Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. J Clin Oncol 2006; 24: 4922-7.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4922-4927
-
-
Dragovich, T.1
McCoy, S.2
Fenoglio-Preiser, C.M.3
-
28
-
-
35348826772
-
A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response
-
Ferry D R, Anderson M, Beddard K etal. A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response. Clin Cancer Res 2007; 13: 5869-75.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5869-5875
-
-
Ferry, D.R.1
Anderson, M.2
Beddard, K.3
-
30
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N, Chang A, Parikh P etal. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005; 366: 1527-37.
-
(2005)
Lancet
, vol.366
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
-
31
-
-
67649213371
-
Epidermal growth factor receptor mutations and the clinical outcome in male smokers with squamous cell carcinoma of lung
-
Park S H, Ha S Y, Lee J I etal. Epidermal growth factor receptor mutations and the clinical outcome in male smokers with squamous cell carcinoma of lung. J Korean Med Sci 2009; 24: 448-52.
-
(2009)
J Korean Med Sci
, vol.24
, pp. 448-452
-
-
Park, S.H.1
Ha, S.Y.2
Lee, J.I.3
-
32
-
-
33846609066
-
EGFR mutations and human papillomavirus in squamous cell carcinoma of tongue and tonsil
-
Na I I, Kang H J, Cho S Y etal. EGFR mutations and human papillomavirus in squamous cell carcinoma of tongue and tonsil. Eur J Cancer 2007; 43: 520-6.
-
(2007)
Eur J Cancer
, vol.43
, pp. 520-526
-
-
Na, I.I.1
Kang, H.J.2
Cho, S.Y.3
-
33
-
-
34250880807
-
Detection of epidermal growth factor receptor mutation in transbronchial needle aspirates of non-small cell lung cancer
-
Horiike A, Kimura H, Nishio K etal. Detection of epidermal growth factor receptor mutation in transbronchial needle aspirates of non-small cell lung cancer. Chest 2007; 131: 1628-34.
-
(2007)
Chest
, vol.131
, pp. 1628-1634
-
-
Horiike, A.1
Kimura, H.2
Nishio, K.3
-
34
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications
-
Kosaka T, Yatabe Y, Endoh H, Kuwano H, Takahashi T, Mitsudomi T. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 2004; 64: 8919-23.
-
(2004)
Cancer Res
, vol.64
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Kuwano, H.4
Takahashi, T.5
Mitsudomi, T.6
-
35
-
-
0023707058
-
Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung
-
Rodenhuis S, Slebos R J, Boot A J etal. Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung. Cancer Res 1988; 48: 5738-41.
-
(1988)
Cancer Res
, vol.48
, pp. 5738-5741
-
-
Rodenhuis, S.1
Slebos, R.J.2
Boot, A.J.3
-
36
-
-
0025334341
-
K-ras activation in colorectal tumors from patients with familial polyposis coli
-
Sasaki M, Sugio K, Sasazuki T. K-ras activation in colorectal tumors from patients with familial polyposis coli. Cancer 1990; 65: 2576-9.
-
(1990)
Cancer
, vol.65
, pp. 2576-2579
-
-
Sasaki, M.1
Sugio, K.2
Sasazuki, T.3
-
37
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 1988; 53: 549-54.
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
38
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H, Lin L, Takahashi T etal. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005; 97: 339-46.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
|