Fatty acids bind tightly to the N-terminal domain of angiopoietin-like protein 4 and modulate its interaction with lipoprotein lipase

Journal of Biological Chemistry

Volumn 287, Issue 35, 2012, Pages 29739-29752

  Robal, Terje ^a   Larsson, Mikael ^b   Martin, Miina ^a   Olivecrona, Gunilla ^b   Lookene, Aivar ^a  

^a TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COILED-COIL DOMAINS; CONFORMATIONAL CHANGE; DIMERIC ENZYME; DISSOCIATION RATES; EQUILIBRIUM DISSOCIATION CONSTANT; FLUORESCENCE PROPERTIES; HELICAL CONTENT; HIGH AFFINITY; HUMAN PLASMAS; ISOTHERMAL TITRATION CALORIMETRY; LINOLEIC AND LINOLENIC ACIDS; LINOLENIC ACIDS; LIPOPROTEIN LIPASE; MYRISTIC ACID; N-TERMINAL DOMAINS; N-TERMINALS; NANOMOLAR RANGE; PLASMA TRIGLYCERIDES; STABLE COMPLEXES; STRUCTURAL STABILITIES;

ASSOCIATION REACTIONS; DISSOCIATION; FLUORESCENCE; OLEIC ACID; OLIGOMERS; SATURATED FATTY ACIDS; STABILITY; UNSATURATED FATTY ACIDS;

LINOLEIC ACID;

ANGIOPOIETIN; ANGIOPOIETIN LIKE PROTEIN 4; FATTY ACID; LINOLEIC ACID; LIPOPROTEIN LIPASE; MYRISTIC ACID; OLEIC ACID; PALMITIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ANGIOPOIETINS; ANIMALS; BINDING SITES; CATTLE; FATTY ACIDS; HUMANS; LIPOPROTEIN LIPASE; MICE; PLASMA; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SERUM ALBUMIN; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE;

EID: 84865455762     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.303529     Document Type: Article

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