Molecular characterization of the type I IFN receptor in two woodchuck species and detection of its expression in liver samples from woodchucks infected with woodchuck hepatitis virus (WHV)

Cytokine

Volumn 60, Issue 1, 2012, Pages 179-185

  Fan, Hebin ^a,d   Zhu, Zhenni ^a   Wang, Yang ^a   Zhang, Xiaoyong ^a,b   Lu, Yinping ^a   Tao, Yuanqing ^c   Fan, Wei ^c   Wang, Zhongdong ^c   Wang, Hu ^c   Roggendorf, Micheal ^b   Lu, Mengji ^a,b   Wang, Baoju ^a   Yang, Dongliang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c Qinghai Institute for Endemic Disease Prevention and Control   (China)

^d 161 Hospital   (China)

Author keywords

Marmota himalayana; Marmota monax; Type i interferon receptor; Woodchuck; Woodchuck hepatitis virus

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERFERON RECEPTOR; MESSENGER RNA; SMALL INTERFERING RNA; TYPE I INTERFERON RECEPTOR 1; TYPE I INTERFERON RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; LIVER; LIVER CELL; MARMOTA HIMALAYANA; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA INTERFERENCE; SEQUENCE ANALYSIS; UPREGULATION; WOODCHUCK; WOODCHUCK HEPATITIS; WOODCHUCK HEPATITIS VIRUS;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CLONING, MOLECULAR; GENE EXPRESSION; GTP-BINDING PROTEINS; HEPATITIS B; HEPATITIS B VIRUS, WOODCHUCK; HEPATOCYTES; HOST-PATHOGEN INTERACTIONS; INTERFERON-ALPHA; INTERFERON-GAMMA; LIVER; MARMOTA; MOLECULAR SEQUENCE DATA; PHYLOGENY; RECEPTOR, INTERFERON ALPHA-BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

HEPATITIS B VIRUS; MARMOTA HIMALAYANA; MARMOTA MONAX; WOODCHUCK HEPATITIS VIRUS;

EID: 84865413083     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.05.013     Document Type: Article

References (37)

1. de Weerd N.A., Samarajiwa S.A., Hertzog P.J. Type I interferon receptors: biochemistry and biological functions. J Biol Chem 2007, 282:20053-20057.
2. Zuniga E.I., Hahm B., Oldstone M.B. Type I interferon during viral infections: multiple triggers for a multifunctional mediator. Curr Top Microbiol Immunol 2007, 316:337-357.
3. Darnell J.J., Kerr I.M., Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264:1415-1421.
4. Guidotti L.G., Chisari F.V. Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 2006, 1:23-61.
5. Williams R. Global challenges in liver disease. Hepatology 2006, 44:521-526.
6. Zhou J., Huang J.D., Poon V.K., Chen D.Q., Chan C.C., Ng F., et al. Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection. J Hepatol 2009, 51:322-332.
7. Zhou J., Lu L., Yuen M.F., Lam T.W., Chung C.P., Lam C.L., et al. Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection. J Hepatol 2007, 46:198-205.
8. Gong Q.M., Kong X.F., Yang Z.T., Xu J., Wang L., Li X.H., et al. Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection. J Viral Hepat 2009, 16:674-680.
9. Frodsham A.J., Zhang L., Dumpis U., Taib N.A., Best S., Durham A., et al. Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence. Proc Natl Acad Sci USA 2006, 103:9148-9153.
10. Meng F., Wang J., Ge J., Fan X., Wang B., Han L., et al. Alteration of interferon-alpha/beta receptors in chronic hepatitis B patients. J Clin Immunol 2011, 31:521-532.
11. Fujiwara D., Hino K., Yamaguchi Y., Kubo Y., Yamashita S., Uchida K., et al. Type I interferon receptor and response to interferon therapy in chronic hepatitis C patients: a prospective study. J Viral Hepat 2004, 11:136-140.
12. Mizukoshi E., Kaneko S., Yanagi M., Ohno H., Kaji K., Terasaki S., et al. Expression of interferon alpha/beta receptor in the liver of chronic hepatitis C patients. J Med Virol 1998, 56:217-223.
13. Morita K., Tanaka K., Saito S., Kitamura T., Kondo M., Sakaguchi T., et al. Expression of interferon receptor genes (IFNAR1 and IFNAR2 mRNA) in the liver may predict outcome after interferon therapy in patients with chronic genotype 2a or 2b hepatitis C virus infection. J Clin Gastroenterol 1998, 26:135-140.
14. Yatsuhashi H., Fujino T., Matsumoto T., Inoue O., Koga M., Yano M. Immunohistochemical analysis of hepatic interferon alpha-beta receptor level: relationship between receptor expression and response to interferon therapy in patients with chronic hepatitis C. J Hepatol 1999, 30:995-1003.
15. Yamaguchi Y., Hino K., Fujiwara D., Ren F., Katoh Y., Satoh Y., et al. Expression of type I interferon receptor in liver and peripheral blood mononuclear cells in chronic hepatitis C patients. Dig Dis Sci 2002, 47:1611-1617.
16. Fukuda R., Ishimura N., Hamamoto S., Moritani M., Uchida Y., Ishihara S., et al. Co-infection by serologically-silent hepatitis B virus may contribute to poor interferon response in patients with chronic hepatitis C by down-regulation of type-I interferon receptor gene expression in the liver. J Med Virol 2001, 63:220-227.
17. Tennant B.C., Gerin J.L. The woodchuck model of hepatitis B virus infection. ILAR J 2001, 42:89-102.
18. Summers J., Smolec J.M., Snyder R. A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks. Proc Natl Acad Sci USA 1978, 75:4533-4537.
19. Roggendorf M., Yang D., Lu M. The woodchuck: a model for therapeutic vaccination against hepadnaviral infection. Pathol Biol (Paris) 2010, 58:308-314.
20. Roggendorf M., Tolle T.K. The woodchuck: an animal model for hepatitis B virus infection in man. Intervirology 1995, 38:100-112.
21. Menne S., Cote P.J. The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection. World J Gastroenterol 2007, 13:104-124.
22. Lu M., Roggendorf M. Evaluation of new approaches to prophylactic and therapeutic vaccinations against hepatitis B viruses in the woodchuck model. Intervirology 2001, 44:124-131.
23. Galibert F., Chen T.N., Mandart E. Localization and nucleotide sequence of the gene coding for the woodchuck hepatitis virus surface antigen: comparison with the gene coding for the human hepatitis B virus surface antigen. Proc Natl Acad Sci USA 1981, 78:5315-5319.
24. Steppan S.J., Akhverdyan M.R., Lyapunova E.A., Fraser D.G., Vorontsov N.N., Hoffmann R.S., et al. Molecular phylogeny of the marmots (Rodentia:Sciuridae): tests of evolutionary and biogeographic hypotheses. Syst Biol 1999, 48:715-734.
25. Wang B.J., Tian Y.J., Meng Z.J., Jiang M., Wei B.Q., Tao Y.Q., et al. Establishing a new animal model for hepadnaviral infection: susceptibility of Chinese Marmota-species to woodchuck hepatitis virus infection. J Gen Virol 2011, 92:681-691.
26. Lu Y., Xu Y., Yang D., Kemper T., Roggendorf M., Lu M. Molecular characterization of woodchuck type I interferons and their expression by woodchuck peripheral blood lymphocytes. Cytokine 2008, 41:127-135.
27. Lu Y., Wang B., Huang H., Tian Y., Bao J., Dong J., et al. The interferon-alpha gene family of Marmota himalayana, a Chinese marmot species with susceptibility to woodchuck hepatitis virus infection. Dev Comp Immunol 2008, 32:445-457.
28. Bazan J.F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 1990, 87:6934-6938.
29. Mogensen K.E., Lewerenz M., Reboul J., Lutfalla G., Uze G. The type I interferon receptor: structure, function, and evolution of a family business. J Interferon Cytokine Res 1999, 19:1069-1098.
30. Owczarek C.M., Hwang S.Y., Holland K.A., Gulluyan L.M., Tavaria M., Weaver B., et al. Cloning and characterization of soluble and transmembrane isoforms of a novel component of the murine type I interferon receptor, IFNAR 2. J Biol Chem 1997, 272:23865-23870.
31. Novick D., Cohen B., Rubinstein M. The human interferon alpha/beta receptor: characterization and molecular cloning. Cell 1994, 77:391-400.
32. Wang B., Lohrengel B., Lu Y., Meng Z., Xu Y., Yang D., et al. Molecular characterization of woodchuck interleukin 15 (wIL-15) and detection of its expression in liver samples of woodchucks infected with woodchuck hepatitis virus (WHV). Cytokine 2005, 32:296-303.
33. Hardy M.P., Hertzog P.J., Owczarek C.M. Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression. Biochem J 2002, 365:355-367.
34. Mizukoshi E., Kaneko S., Yanagi M., Ohno H., Matsushita E., Kobayashi K. Upregulation of type I interferon receptor by IFN-gamma. J Interferon Cytokine Res 1999, 19:1019-1023.
35. Seo Y.J., Hahm B. Type I interferon modulates the battle of host immune system against viruses. Adv Appl Microbiol 2010, 73:83-101.
36. Lu M., Lohrengel B., Hilken G., Kemper T., Roggendorf M. Woodchuck gamma interferon upregulates major histocompatibility complex class I transcription but is unable to deplete woodchuck hepatitis virus replication intermediates and RNAs in persistently infected woodchuck primary hepatocytes. J Virol 2002, 76:58-67.
37. Meng Z., Qiu S., Zhang X., Wu J., Schreiter T., Xu Y., et al. Inhibition of woodchuck hepatitis virus gene expression in primary hepatocytes by siRNA enhances the cellular gene expression. Virology 2009, 384:88-96.