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Volumn 384, Issue 1, 2009, Pages 88-96

Inhibition of woodchuck hepatitis virus gene expression in primary hepatocytes by siRNA enhances the cellular gene expression

Author keywords

Hepadnavirus; IFN stimulated genes; ISGs; RNA interference; RNAi; Woodchuck

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; SMALL INTERFERING RNA;

EID: 58549120152     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.11.012     Document Type: Article
Times cited : (13)

References (53)
  • 2
    • 31544456413 scopus 로고    scopus 로고
    • Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
    • Bartlett D.W., and Davis M.E. Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging. Nucleic Acids Res. 34 (2006) 322-333
    • (2006) Nucleic Acids Res. , vol.34 , pp. 322-333
    • Bartlett, D.W.1    Davis, M.E.2
  • 6
    • 0038419800 scopus 로고    scopus 로고
    • Induction of an interferon response by RNAi vectors in mammalian cells
    • Bridge A.J., Pebernard S., Ducraux A., Nicoulaz A.L., and Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 34 (2003) 263-264
    • (2003) Nat. Genet. , vol.34 , pp. 263-264
    • Bridge, A.J.1    Pebernard, S.2    Ducraux, A.3    Nicoulaz, A.L.4    Iggo, R.5
  • 8
    • 0041331496 scopus 로고    scopus 로고
    • siRNA function in RNAi: a chemical modification analysis
    • Chiu Y.L., and Rana T.M. siRNA function in RNAi: a chemical modification analysis. RNA. 9 (2003) 1034-1048
    • (2003) RNA. , vol.9 , pp. 1034-1048
    • Chiu, Y.L.1    Rana, T.M.2
  • 9
    • 0036200712 scopus 로고    scopus 로고
    • Clinical and immunological efficacy of intradermal vaccine plus lamivudine with or without interleukin-2 in patients with chronic hepatitis B
    • Dahmen A., Herzog-Hauff S., Bocher W.O., Galle P.R., and Lohr H.F. Clinical and immunological efficacy of intradermal vaccine plus lamivudine with or without interleukin-2 in patients with chronic hepatitis B. J. Med. Virol. 66 (2002) 452-460
    • (2002) J. Med. Virol. , vol.66 , pp. 452-460
    • Dahmen, A.1    Herzog-Hauff, S.2    Bocher, W.O.3    Galle, P.R.4    Lohr, H.F.5
  • 10
    • 0043169550 scopus 로고    scopus 로고
    • Hepatitis B virus downregulates the human interferon-inducible MxA promoter through direct interaction of precore/core proteins
    • Fernandez M., Quiroga J.A., and Carreno V. Hepatitis B virus downregulates the human interferon-inducible MxA promoter through direct interaction of precore/core proteins. J. Gen. Virol. 84 (2003) 2073-2082
    • (2003) J. Gen. Virol. , vol.84 , pp. 2073-2082
    • Fernandez, M.1    Quiroga, J.A.2    Carreno, V.3
  • 11
    • 0025906989 scopus 로고
    • Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA
    • Foster G.R., Ackrill A.M., Goldin R.D., Kerr I.M., Thomas H.C., and Stark G.R. Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 2888-2892
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 2888-2892
    • Foster, G.R.1    Ackrill, A.M.2    Goldin, R.D.3    Kerr, I.M.4    Thomas, H.C.5    Stark, G.R.6
  • 14
  • 15
    • 33749054748 scopus 로고    scopus 로고
    • New developments in the treatment of chronic hepatitis B
    • Hadziyannis S.J. New developments in the treatment of chronic hepatitis B. Expert Opin. Biol. Ther. 6 (2006) 913-921
    • (2006) Expert Opin. Biol. Ther. , vol.6 , pp. 913-921
    • Hadziyannis, S.J.1
  • 17
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G.J. RNA interference. Nature 418 (2002) 244-251
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 18
    • 11844306534 scopus 로고    scopus 로고
    • In vivo immunization by vaccine therapy following virus suppression by lamivudine: a novel approach for treating patients with chronic hepatitis B
    • Horiike N., Fazle Akbar S.M., Michitaka K., Joukou K., Yamamoto K., Kojima N., Hiasa Y., Abe M., and Onji M. In vivo immunization by vaccine therapy following virus suppression by lamivudine: a novel approach for treating patients with chronic hepatitis B. J. Clin. Virol. 32 (2005) 156-161
    • (2005) J. Clin. Virol. , vol.32 , pp. 156-161
    • Horiike, N.1    Fazle Akbar, S.M.2    Michitaka, K.3    Joukou, K.4    Yamamoto, K.5    Kojima, N.6    Hiasa, Y.7    Abe, M.8    Onji, M.9
  • 20
    • 0141755412 scopus 로고    scopus 로고
    • Inhibition of HBV replication by siRNA in a stable HBV-producing cell line
    • Konishi M., Wu C.H., and Wu G.Y. Inhibition of HBV replication by siRNA in a stable HBV-producing cell line. Hepatology 38 (2003) 842-850
    • (2003) Hepatology , vol.38 , pp. 842-850
    • Konishi, M.1    Wu, C.H.2    Wu, G.Y.3
  • 21
    • 30344458192 scopus 로고    scopus 로고
    • Cellular and virological mechanisms of HBV drug resistance
    • Locarnini S., and Mason W.S. Cellular and virological mechanisms of HBV drug resistance. J. Hepatol. 44 (2006) 422-431
    • (2006) J. Hepatol. , vol.44 , pp. 422-431
    • Locarnini, S.1    Mason, W.S.2
  • 22
    • 0032889271 scopus 로고    scopus 로고
    • Immunization of woodchucks with plasmids expressing woodchuck hepatitis virus (WHV) core antigen and surface antigen suppresses WHV infection
    • Lu M., Hilken G., Kruppenbacher J., Kemper T., Schirmbeck R., Reimann J., and Roggendorf M. Immunization of woodchucks with plasmids expressing woodchuck hepatitis virus (WHV) core antigen and surface antigen suppresses WHV infection. J. Virol. 73 (1999) 281-289
    • (1999) J. Virol. , vol.73 , pp. 281-289
    • Lu, M.1    Hilken, G.2    Kruppenbacher, J.3    Kemper, T.4    Schirmbeck, R.5    Reimann, J.6    Roggendorf, M.7
  • 23
    • 18144406115 scopus 로고    scopus 로고
    • Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune responses in mice and woodchucks
    • Lu M., Isogawa M., Xu Y., and Hilken G. Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune responses in mice and woodchucks. J. Virol. 79 (2005) 6368-6376
    • (2005) J. Virol. , vol.79 , pp. 6368-6376
    • Lu, M.1    Isogawa, M.2    Xu, Y.3    Hilken, G.4
  • 24
    • 34249993791 scopus 로고    scopus 로고
    • Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model
    • Lu M., Menne S., Yang D., Xu Y., and Roggendorf M. Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model. Expert Opin. Investig. Drugs 16 (2007) 787-801
    • (2007) Expert Opin. Investig. Drugs , vol.16 , pp. 787-801
    • Lu, M.1    Menne, S.2    Yang, D.3    Xu, Y.4    Roggendorf, M.5
  • 26
    • 34547960175 scopus 로고    scopus 로고
    • Small self-RNA generated by RNase L amplifies antiviral innate immunity
    • Malathi K., Dong B., Gale Jr. M., and Silverman R.H. Small self-RNA generated by RNase L amplifies antiviral innate immunity. Nature 448 (2007) 816-819
    • (2007) Nature , vol.448 , pp. 816-819
    • Malathi, K.1    Dong, B.2    Gale Jr., M.3    Silverman, R.H.4
  • 27
    • 4644313122 scopus 로고    scopus 로고
    • Induction or expansion of T-cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers
    • Mancini-Bourgine M., Fontaine H., Scott-Algara D., Pol S., Brechot C., and Michel M.L. Induction or expansion of T-cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers. Hepatology 40 (2004) 874-882
    • (2004) Hepatology , vol.40 , pp. 874-882
    • Mancini-Bourgine, M.1    Fontaine, H.2    Scott-Algara, D.3    Pol, S.4    Brechot, C.5    Michel, M.L.6
  • 28
    • 0036434602 scopus 로고    scopus 로고
    • Advances in therapy for chronic hepatitis B
    • Marcellin P. Advances in therapy for chronic hepatitis B. Semin. Liver Dis. 22 Suppl. 1 (2002) 33-36
    • (2002) Semin. Liver Dis. , vol.22 , Issue.SUPPL. 1 , pp. 33-36
    • Marcellin, P.1
  • 31
    • 34648827820 scopus 로고    scopus 로고
    • Chemoimmunotherapy of chronic hepatitis B virus infection in the woodchuck model overcomes immunologic tolerance and restores T-cell responses to pre-S and S regions of the viral envelope protein
    • Menne S., Tennant B.C., Gerin J.L., and Cote P.J. Chemoimmunotherapy of chronic hepatitis B virus infection in the woodchuck model overcomes immunologic tolerance and restores T-cell responses to pre-S and S regions of the viral envelope protein. J. Virol. 81 (2007) 10614-10624
    • (2007) J. Virol. , vol.81 , pp. 10614-10624
    • Menne, S.1    Tennant, B.C.2    Gerin, J.L.3    Cote, P.J.4
  • 32
    • 0022083293 scopus 로고
    • Transcription of woodchuck hepatitis virus in the chronically infected liver
    • Moroy T., Etiemble J., Trepo C., Tiollais P., and Buendia M.A. Transcription of woodchuck hepatitis virus in the chronically infected liver. EMBO J. 4 (1985) 1507-1514
    • (1985) EMBO J. , vol.4 , pp. 1507-1514
    • Moroy, T.1    Etiemble, J.2    Trepo, C.3    Tiollais, P.4    Buendia, M.A.5
  • 34
    • 1842584178 scopus 로고    scopus 로고
    • Interfering with hepatitis C virus RNA replication
    • Randall G., and Rice C.M. Interfering with hepatitis C virus RNA replication. Virus Res. 102 (2004) 19-25
    • (2004) Virus Res. , vol.102 , pp. 19-25
    • Randall, G.1    Rice, C.M.2
  • 35
    • 34249885360 scopus 로고    scopus 로고
    • Chronic infections with hepatotropic viruses: mechanisms of impairment of cellular immune responses
    • Rehermann B. Chronic infections with hepatotropic viruses: mechanisms of impairment of cellular immune responses. Semin. Liver Dis. 27 (2007) 152-160
    • (2007) Semin. Liver Dis. , vol.27 , pp. 152-160
    • Rehermann, B.1
  • 37
    • 84889837282 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus
    • Thomas T.H., Zuckermann A., and Lemon S. (Eds), Blackwell Publishing Ltd., Oxford
    • Roggendorf M., and Lu M. Woodchuck hepatitis virus. In: Thomas T.H., Zuckermann A., and Lemon S. (Eds). Viral Hepatitis. 3rd ed. (2005), Blackwell Publishing Ltd., Oxford 210-224
    • (2005) Viral Hepatitis. 3rd ed. , pp. 210-224
    • Roggendorf, M.1    Lu, M.2
  • 39
    • 0037382795 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus expression and replication by RNA interference
    • Shlomai A., and Shaul Y. Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology 37 (2003) 764-770
    • (2003) Hepatology , vol.37 , pp. 764-770
    • Shlomai, A.1    Shaul, Y.2
  • 41
    • 0242636380 scopus 로고    scopus 로고
    • Dissecting HIV-1 through RNA interference
    • Stevenson M. Dissecting HIV-1 through RNA interference. Nat. Rev. Immunol. 3 (2003) 851-858
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 851-858
    • Stevenson, M.1
  • 42
    • 0033929057 scopus 로고    scopus 로고
    • Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
    • Stojdl D.F., Lichty B., Knowles S., Marius R., Atkins H., Sonenberg N., and Bell J.C. Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus. Nat. Med. 6 (2000) 821-825
    • (2000) Nat. Med. , vol.6 , pp. 821-825
    • Stojdl, D.F.1    Lichty, B.2    Knowles, S.3    Marius, R.4    Atkins, H.5    Sonenberg, N.6    Bell, J.C.7
  • 43
    • 0018084546 scopus 로고
    • A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks
    • Summers J., Smolec J.M., and Snyder R. A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks. Proc. Natl. Acad. Sci. U. S. A. 75 (1978) 4533-4537
    • (1978) Proc. Natl. Acad. Sci. U. S. A. , vol.75 , pp. 4533-4537
    • Summers, J.1    Smolec, J.M.2    Snyder, R.3
  • 44
    • 0024333523 scopus 로고
    • Transcription of the human beta interferon gene is inhibited by hepatitis B virus
    • Twu J.S., and Schloemer R.H. Transcription of the human beta interferon gene is inhibited by hepatitis B virus. J. Virol. 63 (1989) 3065-3071
    • (1989) J. Virol. , vol.63 , pp. 3065-3071
    • Twu, J.S.1    Schloemer, R.H.2
  • 45
    • 14144255291 scopus 로고    scopus 로고
    • Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs
    • Uprichard S.L., Boyd B., Althage A., and Chisari F.V. Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 773-778
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 773-778
    • Uprichard, S.L.1    Boyd, B.2    Althage, A.3    Chisari, F.V.4
  • 46
    • 36549028324 scopus 로고    scopus 로고
    • Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: a randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudine
    • Vandepapeliere P., Lau G.K., Leroux-Roels G., Horsmans Y., Gane E., Tawandee T., Merican M.I., Win K.M., Trepo C., Cooksley G., Wettendorff M., and Ferrari C. Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: a randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudine. Vaccine 25 (2007) 8585-8597
    • (2007) Vaccine , vol.25 , pp. 8585-8597
    • Vandepapeliere, P.1    Lau, G.K.2    Leroux-Roels, G.3    Horsmans, Y.4    Gane, E.5    Tawandee, T.6    Merican, M.I.7    Win, K.M.8    Trepo, C.9    Cooksley, G.10    Wettendorff, M.11    Ferrari, C.12
  • 47
    • 0035050667 scopus 로고    scopus 로고
    • Purification of woodchuck hepatitis surface antigen using a monoclonal antibody raised against the antigen
    • Waters J.A., O'Neill C., bdul-Gader A., Goldin R., Karayiannis P., and Monjardino J. Purification of woodchuck hepatitis surface antigen using a monoclonal antibody raised against the antigen. J. Virol. Methods 93 (2001) 97-103
    • (2001) J. Virol. Methods , vol.93 , pp. 97-103
    • Waters, J.A.1    O'Neill, C.2    bdul-Gader, A.3    Goldin, R.4    Karayiannis, P.5    Monjardino, J.6
  • 48
    • 5644250628 scopus 로고    scopus 로고
    • Inhibition of hepatitis viral replication by siRNA
    • Wu J., and Nandamuri K.M. Inhibition of hepatitis viral replication by siRNA. Expert. Opin. Biol. Ther. 4 (2004) 1649-1659
    • (2004) Expert. Opin. Biol. Ther. , vol.4 , pp. 1649-1659
    • Wu, J.1    Nandamuri, K.M.2
  • 50
    • 36749058339 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1
    • Wu M., Xu Y., Lin S., Zhang X., Xiang L., and Yuan Z. Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1. J. Gen. Virol. 88 (2007) 3260-3269
    • (2007) J. Gen. Virol. , vol.88 , pp. 3260-3269
    • Wu, M.1    Xu, Y.2    Lin, S.3    Zhang, X.4    Xiang, L.5    Yuan, Z.6
  • 51
    • 16544364359 scopus 로고    scopus 로고
    • Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner
    • Zhang Z., Protzer U., Hu Z., Jacob J., and Liang T.J. Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner. J. Virol. 78 (2004) 4566-4572
    • (2004) J. Virol. , vol.78 , pp. 4566-4572
    • Zhang, Z.1    Protzer, U.2    Hu, Z.3    Jacob, J.4    Liang, T.J.5
  • 52
    • 33646593507 scopus 로고    scopus 로고
    • A conserved linear B-cell epitope at the N-terminal region of woodchuck hepatitis virus core protein (WHcAg)
    • Zhang Z., Tian Y., Li L., Fiedler M., Schmid E., Roggendorf M., Xu Y., Lu M., and Yang D. A conserved linear B-cell epitope at the N-terminal region of woodchuck hepatitis virus core protein (WHcAg). J. Virol. Methods 135 (2006) 17-25
    • (2006) J. Virol. Methods , vol.135 , pp. 17-25
    • Zhang, Z.1    Tian, Y.2    Li, L.3    Fiedler, M.4    Schmid, E.5    Roggendorf, M.6    Xu, Y.7    Lu, M.8    Yang, D.9
  • 53
    • 0036056874 scopus 로고    scopus 로고
    • Characterization of complex B cell epitopes on woodchuck hepatitis virus surface antigens by using plasmids encoding chimeric proteins and DNA immunization
    • Zheng X., Schirmbeck R., Hilken G., Waters J.A., Yang D., Reimann J., Roggendorf M., and Lu M. Characterization of complex B cell epitopes on woodchuck hepatitis virus surface antigens by using plasmids encoding chimeric proteins and DNA immunization. Virology 294 (2002) 342-353
    • (2002) Virology , vol.294 , pp. 342-353
    • Zheng, X.1    Schirmbeck, R.2    Hilken, G.3    Waters, J.A.4    Yang, D.5    Reimann, J.6    Roggendorf, M.7    Lu, M.8


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