Immunohistochemical analysis of hepatic interferon alpha-beta receptor level: Relationship between receptor expression and response to interferon therapy in patients with chronic hepatitis C

Journal of Hepatology

Volumn 30, Issue 6, 1999, Pages 995-1003

  Yatsuhashi, Hiroshi ^a   Fujino, Tatsuya ^a   Matsumoto, Takenori ^a   Inoue, Osami ^a   Koga, Michiaki ^a   Yano, Michitami ^a  

^a Nagasaki Chuo National Hospital   (Japan)

Author keywords

Chronic hepatitis C; HCV RNA levels; Immunohistochemistry; Interferon; Interferon receptor

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR; BETA INTERFERON; PEROXIDASE;

ADULT; AGED; ARTICLE; DRUG RECEPTOR BINDING; DRUG RESPONSE; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME; VIREMIA;

EID: 0033029027     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80252-9     Document Type: Article

References (36)

1. Shindo M, Di Bisceglie AM, Hoofnagle JH. Long-term followup of patients with chronic hepatitis C treated with alpha-interferon. Hepatology. 15:1992;1013-1016.
2. Yatsuhashi H, Inoue O, Inokuchi K, Koga M, Nagataki S, Cha T-A, et al. Short and long-term effects of interferon on serum markers of hepatitis C virus replication. J Gastroenterol Hepatol. 8:1993;1-6.
3. Di Bisceglie A, Martin P, Kassianides C, Lisker-Melman M, Murray L, Waggoner J, et al. Recombinant interferon alpha therapy for chronic hepatitis C: a randomized, double-blind, placebo-controlled trial. N Engl J Med. 321:1989;1506-1510.
4. Davis GL, Balart LA, Schiff ER, Lindsay K, Bodenheimer HC, Perrillo RP, et al. Treatment for chronic hepatitis C with recombinant interferon alpha: a multicenter randomized, controlled trial. N Engl J Med. 321:1989;1501-1506.
5. Marcellin P, Boyer N, Giostra E, Degott C, Courouce AM, Degos F, et al. Recombinant human alpha interferon in patients with chronic non-A, non-B hepatitis: a multicenter randomized controlled trial from France. Hepatology. 13:1991;393-397.
6. Causse X, Godinot H, Chevallier M, Chossegros P, Zoulim F, Ouzan D, et al. Comparison of 1 or 3 MU of interferon alpha 2b and placebo in patients with chronic non-A, non-B hepatitis. Gastroenterology. 101:1991;497-502.
7. Poynard T, Leroy V, Cohard M, Thevenot T, Mathurin P, Opolon P, et al. Meta-analysis of interferon randomized trials in the treatment of viral hepatitis C; effects of dose and duration. Hepatology. 24:1996;778-789.
8. Lin R, Roach E, Zimmerman M, Strasser S, Farrel G. Interferon alpha-2b for chronic hepatitis C: effects of dose increment and duration of treatment on response rates. J Hepatol. 23:1995;487-496.
9. Serfaty L, Giral P, Loria A, Andreani T, Legendre C, Poupon R. Factors predictive of the response to interferon in patients with chronic hepatitis C. J Hepatol. 21:1994;12-17.
10. Pagliaro L, Craxi A, Cammaa C, Tine F, Di Marco V, Lo Jacono O, et al. Interferon-alpha for chronic hepatitis C: an analysis of pretreatment clinical predictors of response. Hepatology. 19:1994;820-828.
11. Hino K, Sainokami S, Shimoda K, Liono S, Wang Y, Okamoto H, et al. Genotypes and titers of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C. J Med Virol. 42:1994;299-305.
12. Kobayashi Y, Watanabe S, Konishi M, Yokoi M, Kakehashi R, Kaito M, et al. Quantitation and typing of serum hepatitis C virus RNA in patients with chronic hepatitis C treated with interferon beta. Hepatology. 18:1993;1319-1325.
13. Yoshioka K, Kakumu S, Wakita T, Ishikawa T, Itoh Y, Takayanagi M, et al. Detection of hepatitis C virus by polymerase chain reaction and response to interferon-alpha therapy: relationship to genotypes of hepatitis C virus. Hepatology. 16:1992;293-299.
14. Tsubota A, Chayama K, Ikeda K, Yasuji A, Koida I, Saitoh S, et al. Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection. Hepatology. 19:1994;1088-1094.
15. Hagiwara H, Hayashi N, Mita E, Takehara T, Kasahara A, Fusamoto H, et al. Quantitative analysis of hepatitis C virus RNA in serum during interferon alpha therapy. Gastroenterology. 104:1993;877-883.
16. Lau JYN, Davis GL, Kniffen J, Qian K-P, Urdea MS, Chan CS, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet. 341:1993;1501-1504.
17. Inokuchi K, Yatsuhashi H, Inoue O, Koga M, Nagataki S, Yano M. Correlation of quantitative HCV-RNA levels using a branched DNA enhanced level amplification assay with therapeutic effects of β-interferon in patients with chronic hepatitis C. Int Hepatol Commun. 2:1994;375-382.
18. Yamada G, Takatani M, Kishi F, Takahashi M, Toshihiko D, Tsuji T, et al. Efficacy of interferon alpha therapy in chronic hepatitis C patients depends primarily on hepatitis C virus RNA level. Hepatology. 22:1995;1351-1354.
19. Shiratori Y, Kato N, Yokosuka O, Imazaki F, Hashimoto E, Hayashi N, et al. Predictors of the efficacy of interferon therapy in chronic hepatitis C virus infection. Tokyo-Chiba Hepatitis Research Group. Gastroenterology. 103:1997;558-566.
20. Tsubota A, Kumada H, Chayama K, Arase Y, Saitoh S, Koida I, et al. Time course of histological changes in patients with a sustained biochemical and virological response to interferon-alpha therapy for chronic hepatitis C virus infection. J Hepatol. 27:1997;49-55.
21. Uze G, Lutfalla G, Gresser I. Genetic transfer of a functional human interferon-α receptor into mouse cells: cloning and expression of its cDNA. Cell. 60:1990;225-234.
22. Novick D, Cohen B, Rubinstein M. The human interferon-α/β receptor: characterization and molecular cloning. Cell. 77:1994;391-400.
23. Fukuda R, Ishimura N, Kushiyama Y, Moriyama N, Ishihara S, Nagasawa S, et al. Effectiveness of interferon-alpha therapy in chronic hepatitis C is associated with the amount of interferonalpha receptor mRNA in the liver. J Hepatol. 26:1997;455-461.
24. Yatsuhashi H, Yamasaki K, Aritomi T, Maria P, Carmen D, Inoue O, et al. Quantitative analysis of interferon-α/β receptor mRNA in the liver of patients with chronic hepatitis C: correlation with serum hepatitis C virus-RNA levels and response to treatment with interferon. J Gastroenterol Hepatol. 12:1997;460-467.
25. Ichida F, Tsuji T, Omata M, Ichida T, Inoue K, Kamimura T, et al. New Inuyama classification; new criteria for histological assessment of chronic hepatitis. Int Hepatol Commun. 6:1996;112-119.
26. Suzuki K, Katoh R, Kawaoi A. Immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) in formalinfixed, paraffin-embedded sections from rat and human tissues. Acta Histochem Cytochem. 25:1992;13-21.
27. Lennard PR. Image analysis for all. Nature. 347:1990;103-104.
28. Tanaka T, Tsukiyama-Kohara K, Yamaguchi K, Yagi S, Tanaka S, Hasegawa A, et al. Significance of specific antibody assay for genotyping of hepatitis C virus. Hepatology. 19:1994;1347-1353.
29. Lau JY, Sheron N, Morris AG, Bomford AB, Alexander GJ, Williams R. Interferon-alpha receptor expression and regulation in chronic hepatitis B virus infection. Hepatology. 13:1991;332-338.
30. Nakajima S, Kuroki T, Shintani M, Kurai O, Takeda T, Nishiguchi S, et al. Changes in interferon receptors on peripheral blood mononuclear cells from patients with chronic hepatitis B being treated with interferon. Hepatology. 12:1990;1261-1265.
31. Navarro S, Colamonici OR, Llombart-Bosch A. Immunohistochemical detection of the type I interferon receptor in human fetal, adult, and neoplastic tissues. Mod Pathol. 9:1996;150-156.
32. Volpes R, van den Oord JJ, De Vos R, Depla E, De Ley M, Desmet VJ. Expression of interferon-gamma receptor in normal and pathological human liver tissue. J Hepatol. 12:1991;195-202.
33. Ishimura N, Fukuda R, Fukumoto S. Relationship between intrahepatic expression of interferon-α receptor mRNA and the histological progress of hepatitis C virus-associated chronic liver diseases. J Gastroenterol Hepatol. 11:1996;712-717.
34. Sata M, Miyajima I, Suzuki H, Ueno T, Tanikawa K. Interferon therapy in patients with HCV related liver cirrhosis. Front Hepatol 94. 1994;46-57 Axel Springer Japan, Tokyo.
35. Miyajima I, Sata M, Gondo K, Suzuki H, Tanigawa K. Interferon accumulation in cirrhotic rat liver. J Viral Hepat. 3:1996;23-27.
36. Martinot-Peignoux M, Marcellin P, Pouteau M, Castlelnau C, Boyer N, Poliquin M, et al. Pretreatment serum HCV-RNA levels and HCV genotype are the main and independent prognostic factors of sustained response to alpha interferon therapy in chronic hepatitis C. Hepatology. 22:1995;1050-1056.