Involvement of nuclear factor kappa B in high-fat diet-related pancreatic fibrosis in rats

Gut and Liver

Volumn 6, Issue 3, 2012, Pages 381-387

  Yan, Ming Xian ^a   Ren, Hong Bo ^b   Kou, Yi ^c   Meng, Min ^d   Li, Yan Qing ^b  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG UNIVERSITY   (China)

^c Beijing Liangxiang Hospital   (China)

^d Department of Gastroenterology   (China)

Author keywords

High fat diet; Intercellular adhesion molecule 1; NF kappa B; Pancreatic fibrosis; Tumor necrosis factor alpha

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIPID DIET; LIPID STORAGE; MALE; NONHUMAN; PANCREATIC STELLATE CELL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

EID: 84865405502     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl.2012.6.3.381     Document Type: Article

References (26)

1. Popov D, Simionescu M, Shepherd PR. Saturated-fat diet induces moderate diabetes and severe glomerulosclerosis in hamsters. Diabetologia 2003;46:1408-1418. (Pubitemid 37297212)
2. Qiu L, List EO, Kopchick JJ. Differentially expressed proteins in the pancreas of diet-induced diabetic mice. Mol Cell Proteomics 2005;4:1311-1318. (Pubitemid 41448718)
3. Fraulob JC, Ogg-Diamantino R, Fernandes-Santos C, Aguila MB, Mandarim-de-Lacerda CA. A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL/6 mice fed a high fat diet. J Clin Biochem Nutr 2010;46:212-223.
4. Borst SE, Conover CF. High-fat diet induces increased tissue expression of TNF-alpha. Life Sci 2005;77:2156-2165. (Pubitemid 41140455)
5. Mathur A, Marine M, Lu D, et al. Nonalcoholic fatty pancreas disease. HPB (Oxford) 2007;9:312-318. (Pubitemid 47271323)
6. Yan MX, Li YQ, Meng M, Ren HB, Kou Y. Long-term high-fat diet induces pancreatic injuries via pancreatic microcirculatory disturbances and oxidative stress in rats with hyperlipidemia. Biochem Biophys Res Commun 2006;347:192-199. (Pubitemid 44026487)
7. Zhang X, Cui Y, Fang L, Li F. Chronic high-fat diets induce oxide injuries and fibrogenesis of pancreatic cells in rats. Pancreas 2008;37:e31-e38.
8. Asaumi H, Watanabe S, Taguchi M, Tashiro M, Otsuki M. Externally applied pressure activates pancreatic stellate cells through the generation of intracellular reactive oxygen species. Am J Physiol Gastrointest Liver Physiol 2007;293:G972-G978. (Pubitemid 350106562)
9. Omary MB, Lugea A, Lowe AW, Pandol SJ. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J Clin Invest 2007;117:50-59. (Pubitemid 46048449)
10. Leung PS, Chan YC. Role of oxidative stress in pancreatic inflammation. Antioxid Redox Signal 2009;11:135-165.
11. Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006;116:3015-3025. (Pubitemid 44684486)
12. Kim F, Pham M, Luttrell I, et al. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circ Res 2007;100:1589-1596. (Pubitemid 46897262)
13. Mews P, Phillips P, Fahmy R, et al. Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 2002;50:535-541. (Pubitemid 34638875)
14. Shek FW, Benyon RC, Walker FM, et al. Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis. Am J Pathol 2002;160:1787-1798. (Pubitemid 34525658)
15. Masamune A, Sakai Y, Kikuta K, Satoh M, Satoh A, Shimosegawa T. Activated rat pancreatic stellate cells express intercellular adhesion molecule-1 (ICAM-1) in vitro. Pancreas 2002;25:78-85. (Pubitemid 34760841)
16. Czakó L, Szabolcs A, Vajda A, et al. Hyperlipidemia induced by a cholesterol-rich diet aggravates necrotizing pancreatitis in rats. Eur J Pharmacol 2007;572:74-81. (Pubitemid 47374676)
17. Gómez JA, Molero X, Vaquero E, Alonso A, Salas A, Malagelada JR. Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol 2004;287:G162-G169. (Pubitemid 38802130)
18. Tasci I, Deveci S, Isik AT, et al. Allopurinol in rat chronic pancreatitis: effects on pancreatic stellate cell activation. Pancreas 2007;35:366-371. (Pubitemid 350307382)
19. Chen F, Castranova V, Shi X, Demers LM. New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases. Clin Chem 1999;45:7-17. (Pubitemid 29036378)
20. Jokelainen K, Reinke LA, Nanji AA. Nf-kappab activation is associated with free radical generation and endotoxemia and precedes pathological liver injury in experimental alcoholic liver disease. Cytokine 2001;16:36-39. (Pubitemid 34925824)
21. Parola M, Robino G. Oxidative stress-related molecules and liver fibrosis. J Hepatol 2001;35:297-306. (Pubitemid 32803489)
22. Hisada S, Shimizu K, Shiratori K, Kobayashi M. Peroxisome proliferator-activated receptor gamma ligand prevents the development of chronic pancreatitis through modulating NF-kappaB-dependent proinflammatory cytokine production and pancreatic stellate cell activation. Rocz Akad Med Bialymst 2005;50:142-147.
23. Strauch ED, Yamaguchi J, Bass BL, Wang JY. Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa Binduced expression of transforming growth factor-beta. J Am Coll Surg 2003;197:974-984. (Pubitemid 38199557)
24. Shinozaki S, Mashima H, Ohnishi H, Sugano K. IL-13 promotes the proliferation of rat pancreatic stellate cells through the suppression of NF-kappaB/TGF-beta1 pathway. Biochem Biophys Res Commun 2010;393:61-65.
25. Ka SM, Huang XR, Lan HY, et al. Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. J Am Soc Nephrol 2007;18:1777-1788.
26. He J, Sun X, Qian KQ, Liu X, Wang Z, Chen Y. Protection of cerulein-induced pancreatic fibrosis by pancreas-specific expression of Smad7. Biochim Biophys Acta 2009;1792:56-60.