Use of aminoglycosides in treatment of infections due to intracellular bacteria

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 11, 2001, Pages 2977-2986

  Maurin, M ^a   Raoult, D ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; KANAMYCIN; STREPTOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC THERAPY; BACTERIAL INFECTION; BRUCELLOSIS; CELL LEVEL; CELL PH; DRUG ACCUMULATION; DRUG EFFICACY; DRUG MECHANISM; DRUG PENETRATION; DRUG UPTAKE; EUKARYOTIC CELL; HUMAN; INTRACELLULAR KILLING; LISTERIOSIS; MYCOBACTERIOSIS; NONHUMAN; PHAGOCYTE; PHARMACODYNAMICS; PHARMACOKINETICS; PLAGUE; PRIORITY JOURNAL; RICKETTSIOSIS; SHORT SURVEY; TULAREMIA;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; HUMANS; PHAGOCYTES;

EID: 0034775866     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.11.2977-2986.2001     Document Type: Short Survey

References (187)

1. Effect of pH of the medium on activity of streptomycin and penicillin
2. Mechanisms of phagocytosis in macrophages
3. In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs
4. Lysosomal response of a murine macrophage-like cell line persistently infected with Coxiella burnetii
5. A review of bartonellosis in Ecuador and in Columbia
6. Bartonellosis in Ecuador: Serosurvey and current status of cutaneous verrucous disease
7. Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH
8. Reporter gene technology to assess activity of antimycobacterial agents in macrophages
9. Histology, immunochemistry, and ultrastructure of the verruga in Carrion's disease
10. Treatment of human brucellosis with doxycycline plus rifampin or doxycycline plus streptomycin
11. An outbreak of febrile gastroenteritis associated with corn contaminated with Listeria monocytogenes
12. Listeria monocytogenes: Synergistic effects of ampicillin and gentamicin
13. Antimicrobial susceptibility testing of Francisella tularensis with a modified Mueller-Hinton broth
14. Macrophages and Brucella
15. Differential trafficking of live and dead Mycobacterium marinum organisms in macrophages
16. Ehrlichia chaffeensis inclusions are early endosomes which selectively accumulate transferrin receptor
17. Sequestration of staphylococci at an inaccessible focus
18. Plague meningitis - A retrospective analysis of cases reported in the United States, 1970-1979
19. Acidification of phagososmes in murine macrophages: Blockade by Nocardia asteroides
20. Assessment of a fluoroquinolone, three beta-lactams, two aminoglycosides, and a cycline in treatment of murine Yersinia pestis infection
21. Autoradiographic evidence for the impermeability of mouse peritoneal macrophages to tritiated streptomycin
22. 3H-dihydrostreptomycin by macrophages in culture
23. In vitro susceptibility of Ehrlichia sennetsu to antibiotics
24. In vitro antibiotic susceptibility of the newly recognized agent of human ehrlichiosis: Ehrlichia chaffeensis
25. Proteinase K-sensitive and filterable phagosome-lysosome fusion inhibiting factor in Afipia felis
26. Bartonella quintana invades and multiplies within endothelial cells in vitro and in vivo and forms intracellular blebs
27. Penetration of antimicrobials into tissue culture cells and leukocytes
28. In vitro susceptibilities of Mycobacterium tuberculosis to 10 antimicrobial agents
29. Antibiotic treatment of experimental pneumonic plague in mice
30. Plague in Vietnam. Clinical observations and treatment with kanamycin
31. Rifampicin in the treatment of osteoarticular infections due to staphylococci
32. Brucellosis: An overview
33. The influence of extracellular and phagolysosomal pH changes on the bactericidal activity of bovine neutrophils against Staphylococcus aureus
34. Tularemia: Treatment failures with outpatient use of ceftriaxone
35. Treatment of tularemia with gentamicin in pediatric patients
36. Intracellular killing of mycobacteria
37. Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic
38. Inhibition of tubercle bacilli in cultured human macrophages by chloroquine used alone and in combination with streptomycin, isoniazid, pyrazinamide, and two metabolites of vitamin D3
39. Inhibition by streptomycin of tubercle bacilli within cultured human macrophages
40. Salmonellosis complications in human bartonellosis
41. Clinical and molecular aspects of the pathogenesis of Staphylococcus aureus bone and joint infections
42. Interactions of Bartonella henselae with vascular endothelial cells
43. Antibiotic susceptibility testing for Chlamydia trachomatis using flow cytometry
44. Rickettsia conorii infection enhances vascular cell adhesion molecule-1-and intercellular adhesion molecule-1-dependent mononuclear cell adherence to endothelial cells
45. Treatment of tuberculous meningitis in adults with a combination of isoniazid, rifampicin and streptomycin: A prospective study
46. Intensive short course chemotherapy in the management of tuberculous meningitis
47. Listericidal and nonlistericidal mouse macrophages differ in complement receptor type 3-mediated phagocytosis of L. monocytogenes and in preventing escape of the bacteria into the cytoplasm
48. Gentamicin kills intracellular Listeria monocytogenes
49. The effect of the pH of the medium on the antibacterial action of penicillin, streptomycin, chloramphenicol, terramycin, and bacitracin
50. Use of lysostaphin to remove cell-adherent staphylococci during in vitro assays of phagocyte function
51. Evaluation of gentamicin and penicillin as a synergistic combination in experimental murine listeriosis
52. The aminoglycosides
53. Histoplasma capsulatum modulates the acidification of phagolysosomes
54. Cerebrospinal fluid drug concentrations and the treatment of tuberculous meningitis
55. Streptomycin and alternative agents for the treatment of tularemia: Reveiw of the literature
56. Tularemia: A 30-year experience with 88 cases
57. Intracellular killing of Brucella melitensis within mouse peritoneal macrophages: Influence of treatment with rifampicin. An ultrastructural study
58. The effect of antibiotics on the growth of Legionella pneumophila in guinea-pig alveolar phagocytes infected in vivo by an aerosol
59. Growth of Francisella tularensis LVS in macrophages: The acidic intracellular compartment provides essential iron required for growth
60. Activation of macrophages for desctruction of Francisella tularensis: Identification of cytokines, effector cells and effector molecules
61. Streptomycin treatment of tularemia
62. Treatment of Brucella canis and Brucella abortus in vitro and in vivo by stable plurilamellar vesicle-encapsulated aminoglycosides
63. In vitro activities of 14 antibiotics against 100 human isolates of Yersinia pestis from a southern African plague focus
64. Host-parasite relationships in brucellosis. I. Infection of normal guinea pig macrophages in tissue culture
65. Mycobacterium leprae surface components intervene in the early phagosome-lysosome fusion inhibition event
66. Inhibition of phagosome-lysosome fusion in macrophages by soluble extracts of virulent Brucella abortus
67. The entry and intracellular multiplication of Francisella tularensis in cultured cells: Its correlation with virulence in experimental mice
68. Multidrug resistance in Yersinia pestis mediated by a transferable plasmid
69. In vitro anti-mycobacterial activity of some new aminoglycoside antibiotics
70. Bartonella bacilliformis stimulates endothelial cells in vitro and is angiogenic in vivo
71. Interactions between live Bartonella bacilliformis and endothelial cells
72. The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments
73. In vitro activities of new macrolides and rifapentine against Brucella spp
74. Effect of chlorpromazine and streptomycin on the survival of Brucella abortus in guinea pig monocytes
75. Leukocyte infection by the granulocytic ehrlichiosis agent is linked to expression of a selectin ligand
76. An epidemic of Oroya fever in the peruvian Andes
77. Reprogramming the phagocytic pathway-intracellular pathogens and their vacuoles
78. Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii
79. Modern chemotherapy for brucellosis in humans
80. In vitro susceptibility of Brucella to various antibiotics
81. Inside the neutrophil phagososme: Oxidants, myeloperoxidase, and bacterial killing
82. Differential interaction with endocytic and exocytic pathways distinguishing parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatis
83. Management of listeriosis
84. Susceptibility of streptomycin-resistant Mycobacterium tuberculosis strains to amikacin
85. Protection of phagocytized bacteria from the killing action of antibiotics
86. Legionella pneumophila inhibits acidification of its phagosome in human monocytes
87. Tuberculous meningitis in adults: An eleven-year review
88. Plague as a biological weapon. Medical and public health management
89. Tularemia
90. Tularemia in children
91. In vitro studies on the interaction between mouse peritoneal macrophages and strains of Salmonella and Escherichia coli
92. Antibiotic uptake by alveolar macrophages
93. Membrane-protein traffic in pathogen-infected cells
94. Intracellular survival of staphylococci
95. Tuberculous meningitis: A 30-year review
96. Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis
97. Inability of gentamicin and fosfomycin to eliminate intracellular Enterobacteriaceae
98. In vitro and in vivo studies of imipenem-cilastatin alone and in combination with gentamicin against Listeria monocytogenes
99. Host cell signalling during Listeria monocytogenes infection
100. Intraphagocytic protection of staphylococci from extracellular penicillin
101. Effect of low intraphagolysosomal pH on antimicrobial activity of antibiotics against ingested staphylococci
102. Listeriosis
103. In vitro antimicrobial susceptibility of Listeria monocytogenes isolated in the UK and other Listeria species
104. In vitro synergy testing of nine antimicrobial combinations against Listeria monocytogenes
105. The action of drugs on intracellular tubercle bacilli
106. The phagocytosis and inactivation of staphylococcus by macrophages of normal rabbits
107. Cellular resistance to infection
108. Killing of intraleukocytic Staphylococcus aureus by rifampin: In vitro and in vivo studies
109. Tick-borne tularemia. An outbreak of lymphadenopathy in children
110. Treatment of tularemia, including pulmonary tularemia, with gentamicin
111. Phagolysosomes of Coxiella burnetii-infected cell lines maintain an acidic pH during persistent infection
112. MICs of 28 antibiotic compounds for 14 Bartonella (formerly Rochalimaea) isolates
113. Bactericidal activity of antibiotics against intracellular Francisella tularensis
114. Antibiotic penetration within eukaryotic cells
115. Phagolysosomal alkalinization and intracellular killing of Staphylococcus aureus by amikacin
116. Optimum treatment of intracellular infection
117. Current knowledge of Bartonella species
118. Tuberculous meningitis
119. Inhibition of intracellular growth of Listeria monocytogenes by antibiotics
120. Comparative efficacies of antibiotics in a rat model of meningoencephalitis due to Listeria monocytogenes
121. Antibiotic synergism against Listeria monocytogenes
122. Antimicrobial susceptibility of clinical isolates of Brucella
123. Endocytosis
124. Lack of bactericidal effect of antibiotics except aminoglycosides on Bartonella (Rochalimaea) henselae
125. Interaction of Yersinia pestis with mouse peritoneal macrophages in vitro
126. Mechanism of Shigella entry into epithelial cells
127. In vitro interactions between rabbit alveolar macrophages and Pasteurella tularensis
128. Facilitated uptake of streptomycin by Kupffer cells during phagocytosis
129. Use of chloramphenicol (chloromycetin) in experimental and human tularemia
130. Francisella tularensis (tularemia)
131. Yersinia pestis - Etiologic agent of plague
132. Gamma interferon limits access of Listeria monocytogenes to the macrophage cytoplasm
133. Antibiotic entry into human polymorphonuclear leukocytes
134. Intracellular location of microorganisms
135. Shell-vial assay: Evaluation of a new technique for determining antibiotic susceptibility, tested in 13 isolates of Coxiella burnetii
136. Acidification of phagosomes containing Salmonella typhimurium in murine macrophages
137. Synergistic action of streptomycin with other antibiotics on intracellular Brucella abortus in vitro
138. Relapse of tularemia after aminoglycoside therapy: Case report and discussion of therapeutic options
139. The survival of staphylococci within human leukocytes
140. In vitro susceptibilities of 27 rickettsiae to 13 antimicrobials
141. In vitro susceptibility of Brucella melitensis to antibiotics
142. Analysis of 106 cases of tularemia
143. Activity of amikacin against mycobacteria in vitro and in murine tuberculosis
144. Activity of gentamycin against mycobacteria in vitro and against Mycobacterium tuberculosis in mice
145. Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri
146. Treatment of tularemia with ciprofloxacin
147. Response to therapy in an experimental rabbit model of meningitis due to Listeria monocytogenes
148. A history of bartonellosis (Carrion's disease)
149. Daniel Carrion's experiment
150. Use of HeLa cells infected with tubercle bacilli for the study of anti-tuberculous drugs
151. Sensibilité aux antibiotiques des souches de Brucella
152. Intracellular fate of Mycobacterium leprae in normal and activated mouse macrophages
153. Phagosome acidification blocked by intracellular Toxoplasma gondii
154. In vitro antimicrobial susceptibilities of strains of Yersinia pestis
155. In vitro susceptibilities of four Bartonella bacilliformis strains to 30 antibiotic compounds
156. Treatment of human brucellosis with netilmicine and doxycycline
157. Treatment of human brucellosis with doxycycline and gentamicin
158. Recognition and optimum treatment of brucellosis
159. Doxycycline-rifampin versus doxycycline-streptomycin in treatment of human brucellosis due to Brucella melitensis
160. Sensitivity of trachoma agent to streptomycin and related antibiotics
161. Rickettsia rickettsii infection of cultured human endothelial cells induces NF-kappaB activation
162. Phagocytosis of M. tuberculosis and M. smegmatis stained with indicator dyes
163. Effects of phagocytosis on antibiotic and nucleoside uptake by human polymorphonuclear leukocytes
164. Removal of surface adherent Staphylococcus aureus in the determination of phagocytosis and intracellular killing by the use of lysostaphin
165. Yersinia pestis grows within phagolysosomes in mouse peritoneal macrophages
166. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase
167. Multiplication of tubercle bacilli within phagocytes in vitro, and effect of streptomycin and isonicotinic acid hydrazide
168. The multiplication of tubercle bacilli within normal phagocytes in tissue culture
169. In vitro susceptibility of Francisella tularensis to fluoroquinolones and treatment of tularemia with norfloxacin and ciprofloxacin
170. The survival of staphylococci within phagocytic cells
171. Plague
172. In vitro activities of six new fluoroquinolones against Bracella melitensis
173. Yersinia pseudotuberculosis blocks the phagosomal acidification of B10.A mouse macrophages through the inhibition of vacuolar H(+)-ATPase activity
174. Antibiotic susceptibility and synergy of clinical isolates of Listeria monocytogenes
175. Uptake and intracellular localization of streptomycin in the lysosomes of cultured fibroblasts
176. Uptake and intracellular localization of kanamycin and gentamycin in the lysosomes of cultured fibroblasts
177. The uptake and intracellular accumulation of aminoglycoside antibiotics in lysosomes of cultured rat fibroblasts
178. Intracellular pharmacokinetics and localization of antibiotics as predictors of their efficacy against intraphagocytic infections
179. Intracellular distribution and activity of antibiotics
180. Treatment of the acute febrile phase of Carrion's disease with chloramphenicol
181. Antimicrobial drugs, microorganisms and phagocytes
182. Use of gentamicin in the isolation of subgroup A Chlamydia
183. Effect of gentamicin on growth of viral, chlamydial, and rickettsial agents in mice and embryonated eggs
184. Activity of antibiotics against Staphylococcus aureus within polymorphonuclears
185. An overview of human brucellosis