SCM-198 attenuates early atherosclerotic lesions in hypercholesterolemic rabbits via modulation of the inflammatory and oxidative stress pathways

Atherosclerosis

Volumn 224, Issue 1, 2012, Pages 43-50

  Zhang, Yanfei ^a   Guo, Wei ^a   Wen, Yadan ^b   Xiong, Qinghui ^a   Liu, Hongrui ^a   Wu, Jian ^a   Zou, Yunzeng ^a   Zhu, Yizhun ^a,b  

^a FUDAN UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Atherosclerosis; Hypercholesterolemia; Inflammation; Leonurine; Oxidative stress; SCM 198

Indexed keywords

ANTIOXIDANT; CATALASE; CD31 ANTIGEN; GELATINASE B; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LEONURINE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; SCM 198; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CELL INFILTRATION; CELL MIGRATION; CHOLESTEROL DIET; DISEASE COURSE; DOSE RESPONSE; DRUG MEGADOSE; ECHOGRAPHY; ENZYME ACTIVITY; HEMODYNAMICS; HYPERCHOLESTEROLEMIA; INFLAMMATION; LIPID PEROXIDATION; MACROPHAGE; MALE; MOLECULAR BIOLOGY; NONHUMAN; OXIDATIVE STRESS; PATHOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ATHEROSCLEROSIS; CHEMOKINE CCL2; GALLIC ACID; HYPERCHOLESTEROLEMIA; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; LIPID PEROXIDATION; LIPIDS; MALE; RABBITS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84865392409     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.06.066     Document Type: Article

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