Association of serum lipid components and obesity with genetic ancestry in an admixed population of elderly women

Genetics and Molecular Biology

Volumn 35, Issue 3, 2012, Pages 575-582

  Lins, Tulio C ^a,b   Pires, Alause S ^a   Paula, Roberta S ^a   Moraes, Clayton F ^a,b   Vieira, Rodrigo G ^a   Vianna, Lucy G ^a   Nobrega, Otávio T ^a,b   Pereira, Rinaldo W ^a,b  

^a UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

^b UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

Dyslipidemia; Genetic ancestry; Lipid profile; Obesity; Postmenopausal women

Indexed keywords

LIPID; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

AGED; AMERICAN INDIAN; ANTHROPOMETRY; ARTICLE; BODY COMPOSITION; BODY MASS; CROSS-SECTIONAL STUDY; DYSLIPIDEMIA; EUROPEAN AMERICAN; FEMALE; GENETIC MARKER; GLUCOSE INTOLERANCE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; NEGRO; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PLESIOMORPHY; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84865380159     PISSN: 14154757     EISSN: 16784685     Source Type: Journal    
DOI: 10.1590/S1415-47572012005000047     Document Type: Article

References (32)

1. Basu A, Tang H, Arnett D, Gu CC, Mosley T, Kardia S, Luke A, Tayo B, Cooper R, Zhu X, et al. (2009) Admixture mapping of quantitative trait loci for BMI in African Americans: Evidence for loci on chromosomes 3q, 5q, and 15q. Obesity 17:1226-1231.
2. Bonilla C, Shriver MD, Parra EJ, Jones A and Fernandez JR (2004a) Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York city. Hum Genet 115:57-68.
3. Bonilla C, Parra EJ, Pfaff CL, Dios S, Marshall JA, Hamman RF, Ferrell RE, Hoggart CL, McKeigue PM and Shriver MD (2004b) Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping. Ann Hum Genet 68:139-153.
4. Bonomo E, Caiaffa WT, Cesar CC, Lopes AC and Lima-Costa MF (2003) Food intake according to socioeconomic and demographic profile: The Bambui Project. Cad Saude Publica 19:1461-1471 (in Portuguese, Abstract in English).
5. Bower JF, Deshaies Y, Pfeifer M, Tanenberg RJ and Barakat HA (2002) Ethnic differences in postprandial triglyceride response to a fatty meal and lipoprotein lipase in lean and obese African American and Caucasian women. Metabolism 51:211-217.
6. Cabrera MA, Gebara OC, Diament J, Nussbacher A, Rosano G and Wajngarten M (2007) Metabolic syndrome, abdominal obesity, and cardiovascular risk in elderly women. Int J Cardiol 114:224-229.
7. Deo RC, Reich D, Tandon A, Akylbekova E, Patterson N, Waliszewska A, Kathiresan S, Sarpong D, Taylor Jr HA and Wilson JG (2009) Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: The Jackson Heart Study. PLoS Genetics 5:e1000342.
8. Deurenberg P, Yap M and van Staveren WA (1998) Body mass index and percent body fat: A meta analysis among different ethnic groups. Int J Obes Relat Metab Disord 22:1164-1171.
9. Diretrizes (2007) V Brazilian guidelines in arterial hypertension. Arq Bras Cardiol 89:e24-79 (in Portuguese).
10. Fernandez JR, Shriver MD, Beasley TM, Rafla-Demetrious N, Parra E, Albu J, Nicklas B, Ryan AS, McKeigue PM, Hoggart CL, et al. (2003) Association of African genetic admixture with resting metabolic rate and obesity among women. Obes Res 11:904-911.
11. Gentil P, Lima RM, Lins TC, Abreu BS, Pereira RW and Oliveira RJ (2007) Physical activity, Cdx-2 genotype, and BMD. Int J Sports Med 28:1065-1069.
12. Gentil P, de Lima Lins TC, Lima RM, de Abreu BS, Grattapaglia D, Bottaro M, de Oliveira RJ and Pereira RW (2009) Vitamin-D-receptor genotypes and bone-mineral density in postmenopausal women: Interaction with physical activity. J Aging Phys Act 17:31-45.
13. Lai CQ, Tucker KL, Choudhry S, Parnell LD, Mattei J, Garcia-Bailo B, Beckman K, Burchard EG and Ordovas JM (2009) Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet 125:199-209.
14. Lins TC, Nogueira LR, Lima RM, Gentil P, Oliveira RJ and PereiraRW(2007) A multiplex single-base extension protocol for genotyping Cdx2, FokI, BsmI, ApaI, and TaqI polymorphisms of the vitamin D receptor gene. Genet Mol Res 6:216-224.
15. Lins TC, Vieira RG, Abreu BS, Grattapaglia D and Pereira RW (2010) Genetic composition of Brazilian population samples based on a set of twenty-eight ancestry informative SNPs. Am J Hum Biol 22:187-192.
16. Lins TC, Vieira RG, Abreu BS, Gentil P, Moreno-Lima R, Oliveira RJ and Pereira RW (2011) Genetic heterogeneity of self-reported ancestry groups in an admixed Brazilian population. J Epidemiol 21:240-245.
17. Moreno Lima R, Silva de Abreu B, Gentil P, Cesar de Lima Lins T, Grattapaglia D, PereiraRWand Jaco de Oliveira R (2007) Lack of association between vitamin D receptor genotypes and haplotypes with fat-free mass in postmenopausal Brazilian women. J Gerontol A Biol Sci Med Sci 62:966-972.
18. Nobrega OT, Faleiros VP and Telles JL (2009) Gerontology in the developing Brazil: Achievements and challenges in public policies. Geriatr Gerontol Int 9:135-139.
19. Nobrega OT, Paula RS, Silveira SR, Pires AS, Toledo JO, Moraes CF and Cordova C (2011) Usual dietary intake and cardiovascular risk factors in older Brazilian women. Aging Clin Exp Res DOI: 10.3275/7674.
20. Paula RS, Souza VC, Benedet AL, Souza ER, Toledo JO, Moraes CF, Gomes L, Alho CS, Cordova C and Nobrega OT (2010) Dietary fat and apolipoprotein genotypes modulate plasma lipoprotein levels in Brazilian elderly women. Mol Cell Biochem 337:307-315.
21. Perissinotto E, Pisent C, Sergi G and Grigoletto F (2002) Anthropometric measurements in the elderly: Age and gender differences. Br J Nutr 87:177-186.
22. Philippi ST (2002) Tabela de Composição de Alimentos: Suporte para Decisão Nutricional. Coronário, São Paulo, 135 pp.
23. Ruiz-Narvaez EA, Bare L, Arellano A, Catanese J and Campos H (2010) West African and Amerindian ancestry and risk of myocardial infarction and metabolic syndrome in the Central Valley population of Costa Rica. Hum Genet 127:629-638.
24. Shriver MD, Mei R, Parra EJ, Sonpar V, Halder I, Tishkoff SA, Schurr TG, Zhadanov SI, Osipova LP, Brutsaert TD, et al. (2005) Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Hum Genomics 2:81-89.
25. Sichieri R (2002) Dietary patterns and their associations with obesity in the Brazilian city of Rio de Janeiro. Obes Res 10:42-48.
26. Sichieri R, Castro JF and Moura AS (2003) Factors associated with dietary patterns in the urban Brazilian population. Cad Saude Publica 19(Suppl 1):S47-53 (in Portuguese, Abstract in English).
27. Smith MW, Patterson N, Lautenberger JA, Truelove AL, McDonald GJ, Waliszewska A, Kessing BD, Malasky MJ, Scafe C, Le E, et al. (2004) A high-density admixture map for disease gene discovery in African Americans. Am J Hum Genet 74:1001-1013.
28. Sposito AC, Caramelli B, Fonseca FA, Bertolami MC, Afiune Neto A, Souza AD, Lottenberg AM, Chacra AP, Faludi AA, Loures-Vale AA, et al. (2007) IV Brazilian Guideline for Dyslipidemia and Atherosclerosis Prevention: Department of Atherosclerosis of the Brazilian Society of Cardiology. Arq Bras Cardiol 88(Suppl 1):2-19 (in Portuguese, Abstract in English).
29. Sullivan PW, Morrato EH, Ghushchyan V, Wyatt HR and Hill JO (2005) Obesity, inactivity, and the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the U.S., 2000-2002. Diabetes Care 28:1599-1603.
30. Tsai H-J, Choudhry S, Naqvi M, Rodriguez-Cintron W, Burchard E and Ziv E (2005) Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet 118:424-433.
31. Wilson PW and Kannel WB (2002) Obesity, diabetes, and risk of cardiovascular disease in the elderly. Am J Geriatr Cardiol 11:119-125.
32. Wulan SN, Westerterp KR and Plasqui G (2010) Ethnic differences in body composition and the associated metabolic profile: A comparative study between Asians and Caucasians. Maturitas 65:315-319.