β-amyloid decreases detectable endothelial nitric oxide synthase in human erythrocytes: A role for membrane acetylcholinesterase

Cell Biochemistry and Function

Volumn 30, Issue 6, 2012, Pages 474-479

  Misiti, Francesco ^a   Carelli Alinovi, Cristiana ^a   Sampaolese, Beatrice ^c   Giardina, Bruno ^b,c  

^a UNIVERSITY OF CASSINO AND SOUTHERN LAZIO   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c CATHOLIC UNIVERSITY   (Italy)

Author keywords

Acetylcholinesterase; Amyloid beta peptide; Erythrocytes; Nitric oxide synthase; NO metabolites

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRATE; NITRITE; PROPIDIUM IODIDE;

ALZHEIMER DISEASE; ARTICLE; BRAIN CAPILLARY; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NORMAL HUMAN; PRIORITY JOURNAL;

ACETYLCHOLINESTERASE; AMYLOID BETA-PEPTIDES; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; HUMANS; NITRATES; NITRIC OXIDE SYNTHASE TYPE III; NITRITES;

EID: 84865379516     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.2822     Document Type: Article

References (40)

1. Selkoe DJ. Alzheimer's disease genes proteins and therapy. Physiol Rev 2001; 81: 741-766.
2. Hardy JA, Higgins GA. Alzheimer's disease: the amyloid cascade hypothesis. Science 1992; 256: 184-185.
3. Roychaudhuri R, Yang M, Hoshi MM, Teplow DB. Amyloid β-protein assembly and Alzheimer disease. J Biol Chem 2009; 284: 4749-4753.
4. Nunomura A, Perry G, Aliev G. Oxidative damage is the earliest event in Alzheimer disease. J Neuropath Exp Neuro 2001; 60: 759-767.
5. Chen M, Inestrosa GS, Ross HL, Fernanadez HL. Platelets are the primary source of amyloid beta-peptide in human blood. Biochem Biophys Res Commun 1995; 213: 96-103.
6. Seubert P, Vigo-Pelfrey C, Esch F, Lee M, Dovey H, Davis D. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 1992; 359: 325-327.
7. Grammas P, Yamada M, Zlokovic B. The cerebromicrovasculature: a key player in the pathogenesis of Alzheimer's Disease. J Alzheimers Dis 2002; 4: 217-223.
8. Kuo YM, Kokjohn TA, Beach TG, Sue LI, Brune D, Lopez JC. Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains. J Biol Chem 2001; 276: 12991-12998.
9. Kay MM, Goodman J. Auto-antibodies to band 3 during aging and disease and aging interventions. Ann NY Acad Sci 1994; 719: 419-447.
10. Engstrom I, Ronquist G, Pettersson L, Waldenstrom A. Alzheimer amyloid beta-peptides exhibit ionophore-like properties in human erythrocytes. Eur J Clin Invest 1995; 25: 471-476.
11. Delibas N, Ozcankaya R, Altuntas I. Clinical importance of erythrocyte malondialdehyde levels as a marker for cognitive deterioration in patients with dementia of Alzheimer type A repeated study in 5-year interval. Clin Biochem 2002; 32: 137-141.
12. Jayakumar R, Kusiak JW, Chrest FJ, Femehin AA, Murali J, Werst RP. Red cell perturbations by amyloid beta-protein. Biochim Biophys Acta 2003; 1622: 20-28.
13. Blass JP, Hanin I, Barclay L, Kopp U, Reding MJ. Red blood cell abnormalities in Alzheimer disease. J Am Geriatr Soc 1985; 33: 401-405.
14. Clementi ME, Martorana GE, Pezzotti M, Giardina B, Misiti F. Methionine 35 oxidation reduces toxic effects of the amyloid beta-protein fragment (31-35) on human red blood cell. Int J Biochem Cell Biol 2004; 36(10): 2066-76.
15. De la Torre JC. Vascular basis of Alzheimer's pathogenesis. Ann N Y Acad Sci 2002; 977: 196-215.
16. Mohanty JG, Eckley DM, Williamson JD, Launer LJ, Rifkind JM. Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease? Adv Exp Med Biol 2008; 614: 29-35.
17. Rifkind JM, Abugo OO, Nagababu E, Ramasamy S, Demehin A, Jayakumar R. 2002 In Advances in Cell Aging and Gerontology, T. Hagen (eds); Elsevier: New York; 283-307.
18. Bor-Kucukatay M, Wenby RB, Meiselman HJ, Baskurt OK. Effects of nitric oxide on red blood cell deformability. Am J Physiol Heart Circ Physiol 2003; 284: H1577-H1584.
19. Chen LY, Mehta JL. Evidence for the presence of l-arginine-nitric oxide pathway in human red blood cells: relevance in the effects of red blood cells on platelet function. J Cardiovasc Pharmacol 1998; 32: 57-61.
20. Kleinbongard P, Schulz R, Rassaf T, et al. Red blood cells express a functional endothelial nitric oxide synthase. Blood 2006; 107: 2943-2951.
21. Alvarez A, Alarcón R, Opazo C, et al. Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. J Neurosci 1998; 18(9): 3213-23.
22. Inestrosa NC, Alvarez A, Pérez CA, et al. Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. J Neuron 1996; 16(4): 881-91.
23. Wright DL, Plummer DT. Multiple forms of acetylcholinesterase from human erythrocytes. Biochem J 1973; 133(3): 521-7.
24. Piacentini R, Ripoli C, Leone L, et al. Role of methionine 35 in the intracellular Ca2+ homeostasis dysregulation and Ca2+-dependent apoptosis induced by amyloid beta-peptide in human neuroblastoma IMR32 cells. J Neurochem 2008; 107(4): 1070-82.
25. Bloch W, Mehlhorn U, Krahwinkel A, et al. Ischemia increases detectable endothelial nitric oxide synthase in rat and human myocardium. Nitric Oxide 2001; 5(4): 317-33.
26. Ludolph B, Bloch W, Kelm M, Schulz R, Kleinbongard P. Short-term effectof the HMG-CoA reductase inhibitor rosuvastatin on erythrocyte nitric oxidesynthase activity. Vasc Health Risk Manag 2007; 3: 1069-1073.
27. Ellman GL, Courtney KD, Anders V, Featherstone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961; 7: 88-95.
28. Kleinbongard P, Dejam A, Lauer T, et al. Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals. Free Radic Biol Med 2003; 8: 790-6.
29. Blass JP, Hanin I, Barclay L, Kopp U, Reding MJ. Red blood cell abnormalities in Alzheimer disease. J Am Geriatr Soc 1985; 33: 401-405.
30. Ravi LB, Mohanty JG, Chrest FJ, et al. Influence of beta-amyloid fibrils on the interactions between red blood cells and endothelial cells. JM Neurol Res 2004; 26(5): 579-85.
31. Deliconstantinos G, Villiotou V, Stavrides JC, Salemes N, Gogas J. Nitric oxide and peroxynitrite production by human erythrocytes: a causative factor of toxic anemia in breast cancer patients. Anticancer Res 1995; 15: 1435-1446.
32. Mallozzi C, Di Stasi AM, Minetti M. Peroxynitrite modulates tyrosine-dependent signal transduction pathway of human erythrocyte band 3. FASEB J 1997; 11: 1281-1290.
33. Gentile MT, Vecchione C, Maffei A, et al. Mechanisms of soluble beta-amyloid impairment of endothelial function. J Biol Chem 2004; 279(46): 48135-42.
34. Ozüyaman B, Grau M, Kelm M, Merx MW, Kleinbongard P. RBC NOS: regulatory mechanisms and therapeutic aspects. Trends Mol Med 2008; 14(7): 314-22.
35. Pott C, Steinritz D, Bölck B, et al. eNOS translocation but not eNOS phosphorylation is dependent on intracellular Ca2+ in human atrial myocardium. Am J Physiol Cell Physiol 2006; 290(5): C1437-45.
36. Nicolay JP, Gatz S, Liebig G, Gulbins E, Lang F. Amyloid induced suicidal erythrocyte death. Cell Physiol Biochem 2007; 19(1-4): 175-84.
37. Aloin B, Livine A. Acetylcholinesterase as probe for erythrocyte membrane intactness. Biochem. Biophys. Acta 1974; 339: 359-366.
38. Wilson IB, Quan C. Acetyl-cholinesterase studies on molecular complementarity. Arch Biochem Biophys 1958; 73: 131-143.
39. Taylor P, Lappi S. Interaction of fluorescence probes with acetylcholinesterase. The site and specificity of propidium binding. Biochemistry 1975; 14: 1989-1997.
40. Clementi ME, Giardina B, Colucci D, Galtieri A, Misiti F. Amyloid-beta peptide affects the oxygen dependence of erythrocyte metabolism a role for caspase 3. Int J Biochem Cell Biol 2007; 39(4): 727-35.