In vivo divisional tracking of hematopoietic stem cells

Annals of the New York Academy of Sciences

Volumn 1266, Issue 1, 2012, Pages 40-46

  Takizawa, Hitoshi ^a   Manz, Markus G ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Active cycling; Divisional history; Hematopoietic stem cell division; Labeling technique; Quiescence

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; 7 AMINODACTINOMYCIN; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CD150 ANTIGEN; CD48 ANTIGEN; CYTOPLASM PROTEIN; DNA; GREEN FLUORESCENT PROTEIN; HISTONE H2B; KI 67 ANTIGEN; PROPIDIUM IODIDE; PYRONINE; TOLL LIKE RECEPTOR;

ARTICLE; CELL ACTIVATION; CELL DIVISION; CELL SURFACE; CELL TRACKING; CHEMICAL LABELING; CYTOKINE RESPONSE; CYTOPLASM; DNA PROTEIN COMPLEX; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; IN VIVO STUDY; INTRACELLULAR SIGNALING; NONHUMAN; PROTEIN EXPRESSION; STEADY STATE; T LYMPHOCYTE;

EID: 84865370460     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2012.06500.x     Document Type: Article

References (41)

1. Kiel, M.J., O.H. Yilmaz, T. Iwashita, et al 2005. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121: 1109-1121.
2. Osawa, M., K. Hanada, H. Hamada & H. Nakauchi 1996. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273: 242-245.
3. Takizawa, H., R.R. Regoes, C.S. Boddupalli, et al 2011. Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation. J. Exp. Med. 208: 273-284.
4. Notta, F., S. Doulatov, E. Laurenti, et al 2011. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science 333: 218-221.
5. Dykstra, B., D. Kent, M. Bowie, et al 2007. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell 1: 218-229.
6. Milyavsky, M., O.I. Gan, M. Trottier, et al 2010. A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal. Cell Stem Cell 7: 186-197.
7. Mohrin, M., E. Bourke, D. Alexander, et al 2010. Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. Cell Stem Cell 7: 174-185.
8. Lane, A.A. & D.T. Scadden 2010. Stem cells and DNA damage: persist or perish? Cell 142: 360-362.
9. Seita, J., D.J. Rossi & I.L. Weissman 2010. Differential DNA damage response in stem and progenitor cells. Cell Stem Cell 7: 145-147.
10. Wilson, A. & A. Trumpp 2006. Bone-marrow haematopoietic-stem-cell niches. Nat. Rev. Immunol. 6: 93-106.
11. Scholzen, T. & J. Gerdes 2000. The Ki-67 protein: from the known and the unknown. J. Cell Physiol. 182: 311-322.
12. Passegue, E., A.J. Wagers, S. Giuriato, et al 2005. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J. Exp. Med. 202: 1599-1611.
13. Bowie, M.B., K.D. McKnight, D.G. Kent, et al 2006. Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J. Clin. Invest. 116: 2808-2816.
14. Cheshier, S.H., S.J. Morrison, X. Liao & I.L. Weissman 1999. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc. Natl. Acad. Sci. U.S.A. 96: 3120-3125.
15. Kiel, M.J., S. He, R. Ashkenazi, et al 2007. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449: 238-242.
16. Tumbar, T., G. Guasch, V. Greco, et al 2004. Defining the epithelial stem cell niche in skin. Science 303: 359-363.
17. Foudi, A., K. Hochedlinger, D. Van Buren, et al 2009. Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nat. Biotechnol. 27: 84-90.
18. Wilson, A., E. Laurenti, G. Oser, et al 2008. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135: 1118-1129.
19. Challen, G.A. & M.A. Goodell 2008. Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells. PLoS One 3: e2357.
20. Nygren, J.M. & D. Bryder 2008. A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal. PLoS One 3: e3710.
21. Lyons, A.B. & C.R. Parish 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171: 131-137.
22. Weston, S.A. & C.R. Parish 1990. New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy. J. Immunol. Methods 133: 87-97.
23. Kay, H.E. 1965. How many cell-generations? Lancet 2: 418-419.
24. Drize, N.J., J.R. Keller & J.L. Chertkov 1996. Local clonal analysis of the hematopoietic system shows that multiple small short-living clones maintain life-long hematopoiesis in reconstituted mice. Blood 88: 2927-2938.
25. Jordan, C.T. & I.R. Lemischka 1990. Clonal and systemic analysis of long-term hematopoiesis in the mouse. Genes Dev. 4: 220-232.
26. Lemischka, I.R., D.H. Raulet & R.C. Mulligan 1986. Developmental potential and dynamic behavior of hematopoietic stem cells. Cell 45: 917-927.
27. McKenzie, J.L., O.I. Gan, M. Doedens, et al 2006. Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment. Nat. Immunol. 7: 1225-1233.
28. Guenechea, G., O.I. Gan, C. Dorrell & J.E. Dick 2001. Distinct classes of human stem cells that differ in proliferative and self-renewal potential. Nat. Immunol. 2: 75-82.
29. Lu, R., N.F. Neff, S.R. Quake & I.L. Weissman 2011. Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat. Biotechnol. 29: 928-933.
30. Glauche, I., K. Moore, L. Thielecke, et al 2009. Stem cell proliferation and quiescence-two sides of the same coin. PLoS Comput. Biol. 5: e1000447.
31. Rufer, N., T.H. Brummendorf, S. Kolvraa, et al 1999. Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J. Exp. Med. 190: 157-167.
32. Trumpp, A., M. Essers & A. Wilson 2010. Awakening dormant haematopoietic stem cells. Nat. Rev. Immunol. 10: 201-209.
33. Baldridge, M.T., K.Y. King, N.C. Boles, et al 2010. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature 465: 793-797.
34. Essers, M.A., S. Offner, W.E. Blanco-Bose, et al 2009. IFN alpha activates dormant haematopoietic stem cells in vivo. Nature 458: 904-908.
35. Sato, T., N. Onai, H. Yoshihara, et al 2009. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat. Med. 15: 696-700.
36. Massberg, S., P. Schaerli, I. Knezevic-Maramica, et al 2007. Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell 131: 994-1008.
37. Nagai, Y., K.P. Garrett, S. Ohta, et al 2006. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 24: 801-812.
38. Schmid, M.A., H. Takizawa, D.R. Baumjohann, et al 2011. Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes. Blood 118: 4829-4840.
39. Esplin, B.L., T. Shimazu, R.S. Welner, et al 2011. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J. Immunol. 186: 5367-5375.
40. Takizawa, H. & M.G. Manz 2011. Dynamic regulation of hematopoietic stem cell cycling. Cell Cycle 10: 2246-2247.
41. Li, L. & H. Clevers 2010. Coexistence of quiescent and active adult stem cells in mammals. Science 327: 542-545.