Long-term expression of glial cell line-derived neurotrophic factor slows, but does not stop retinal degeneration in a model of retinitis pigmentosa

Journal of Neurochemistry

Volumn 122, Issue 5, 2012, Pages 1047-1053

  Ohnaka, Masayuki ^a   Miki, Katsuaki ^a   Gong, Yuan Yuan ^a   Stevens, Rebecca ^a   Iwase, Takeshi ^a   Hackett, Sean F ^a   Campochiaro, Peter A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; cone photoreceptors; electroretinograms

Indexed keywords

DOXYCYCLINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B WAVE; CELL DENSITY; CONTROLLED STUDY; ELECTRORETINOGRAM; GENOTYPE; MOUSE; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA CONE; RETINA DEGENERATION; RETINITIS PIGMENTOSA;

AGE FACTORS; ANIMALS; DISEASE MODELS, ANIMAL; DOXYCYCLINE; ELECTRORETINOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; EYE PROTEINS; GENE EXPRESSION REGULATION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; ION CHANNELS; MICE; MICE, TRANSGENIC; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; RETINITIS PIGMENTOSA; RETINOL-BINDING PROTEINS; RNA, MESSENGER;

MUS;

EID: 84865341729     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07842.x     Document Type: Article

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