ERα/E2 signaling suppresses the expression of steroidogenic enzyme genes via cross-talk with orphan nuclear receptor Nur77 in the testes

Molecular and Cellular Endocrinology

Volumn 362, Issue 1-2, 2012, Pages 91-103

  Lee, Seung Yon ^a   Park, Eunsook ^a   Kim, Seung Chang ^a   Ahn, Ryun Sup ^b   Ko, CheMyong ^c   Lee, Keesook ^a  

^a Chonnam National University   (South Korea)

^b Graduate School of Complementary and Alternative Medicine   (South Korea)

^c University of Illinois   (United States)

Author keywords

Estrogen; Estrogen receptor alpha; Leydig cell; Nur77; Steroidogenesis; Testis

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CYCLIC AMP; CYTOCHROME P450C17; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; NUCLEAR RECEPTOR NUR77; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE;

3BETA HSD GENE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEYDIG CELL; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; P450C17 GENE; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; STAR GENE; STEROIDOGENESIS; TRANSACTIVATION; WILD TYPE;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOWN-REGULATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HEK293 CELLS; HUMANS; LEYDIG CELLS; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; PHOSPHOPROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTOR CROSS-TALK; SIGNAL TRANSDUCTION; TESTIS; TESTOSTERONE;

EID: 84865305940     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.05.015     Document Type: Article

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