Direct effects of diethylstilbestrol on the gene expression of the cholesterol side-chain cleavage enzyme (P450scc) in testicular Leydig cells

Life Sciences

Volumn 87, Issue 9-10, 2010, Pages 281-285

  Warita, Katsuhiko ^a,b   Mitsuhashi, Tomoko ^b   Sugawara, Teruo ^c   Tabuchi, Yoshiaki ^d   Tanida, Takashi ^b,e   Wang, Zhi Yu ^a   Matsumoto, Yoshiki ^a   Yokoyama, Toshifumi ^b   Kitagawa, Hiroshi ^b   Miki, Takanori ^a   Takeuchi, Yoshiki ^a   Hoshi, Nobuhiko ^b  

^a KAGAWA UNIVERSITY   (Japan)

^b KOBE UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF TOYAMA   (Japan)

^e KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cholesterol side chain cleavage enzyme (P450scc); Estrogenic endocrine disruptor; Histone acetylation; Leydig cells; Steroidogenesis

Indexed keywords

CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIC AMP; DIETHYLSTILBESTROL; ENDOCRINE DISRUPTOR; ESTRADIOL; HISTONE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEACETYLATION; GENE EXPRESSION; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; TRANSCRIPTION INITIATION;

ACETYLATION; ANDROGENS; ANIMALS; CELL LINE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHROMATIN IMMUNOPRECIPITATION; DIETHYLSTILBESTROL; ENDOCRINE DISRUPTORS; ESTRADIOL; GENE EXPRESSION; LEYDIG CELLS; MALE; MICE; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 77955775427     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.06.020     Document Type: Article

References (34)

1. Arai Y., Mori T., Suzuki Y., Bern H.A. Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. International Review of Cytology 1983, 84:235-268.
2. Chen Y.C., Nagpal M.L., Stocco D.M., Lin T. Effects of genistein, resveratrol, and quercetin on steroidogenesis and proliferation of MA-10 mouse Leydig tumor cells. The Journal of Endocrinology 2007, 192(3):527-537.
3. Chung B.C., Guo I.C., Chou S.J. Transcriptional regulation of the CYP11A1 and ferredoxin genes. Steroids 1997, 62(1):37-42.
4. Clark B.J., Wells J., King S.R., Stocco D.M. The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). Journal of Biological Chemistry 1994, 269(45):28314-28322.
5. Colborn T., vom Saal F.S., Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environmental Health Perspectives 1993, 101(5):378-384.
6. Cooke P.S., Young P., Hess R.A., Cunha G.R. Estrogen receptor expression in developing epididymis, efferent ductules, and other male reproductive organs. Endocrinology 1991, 128(6):2874-2879.
7. Duan H., Cherradi N., Feige J.J., Jefcoate C. cAMP-dependent posttranscriptional regulation of steroidogenic acute regulatory (STAR) protein by the zinc finger protein ZFP36L1/TIS11b. Molecular Endocrinology 2009, 23(4):497-509.
8. Fisher J.S., Millar M.R., Majdic G., Saunders P.T.K., Fraser H.M., Sharpe R.M. Immunolocalisation of oestrogen receptor-α (ERα) within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood. Journal of Endocrinology 1997, 153(3):485-495.
9. 4 isomerase enzyme of cultured Leydig tumor cells. Endocrinology 1985, 117(5):2127-2133.
10. Goyal H.O., Braden T.D., Mansour M., Williams C.S., Kamaleldin A., Srivastava K.K. Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology. Biology of Reproduction 2001, 64(3):927-934.
11. Grunstein M. Histone acetylation in chromatin structure and transcription. Nature 1997, 389(6649):349-352.
12. Guyot R., Odet F., Leduque P., Forest M.G., Le Magueresse-Battistoni B. Diethylstilbestrol inhibits the expression of the steroidogenic acute regulatory protein in mouse fetal testis. Molecular and Cellular Endocrinology 2004, 220(1-2):67-75.
13. Hiroi H., Christenson L.K., Strauss J.F. Regulation of transcription of the steroidogenic acute regulatory protein (StAR) gene: temporal and spatial changes in transcription factor binding and histone modification. Molecular and Cellular Endocrinology 2004, 215(1-2):119-126.
14. Houk C.P., Pearson E.J., Martinelle N., Donahoe P.K., Teixeira J. Feedback inhibition of steroidogenic acute regulatory protein expression in vitro and in vivo by androgens. Endocrinology 2004, 145(3):1269-1275.
15. Iguchi T., Watanabe H., Katsu Y., Mizutani T., Miyagawa S., Suzuki A., Kohno S., Sone K., Kato H. Developmental toxicity of estrogenic chemicals on rodents and other species. Congenital Anomalies 2002, 42(2):94-105.
16. Kim H.H., Kwak D.H., Yon J.M., Baek I.J., Lee S.R., Lee J.E., Nahm S.S., Jeong J.H., Lee B.J., Yun Y.W., Nam S.Y. Differential expression of 3β-hydroxysteroid dehydrogenase mRNA in rat testes exposed to endocrine disruptors. Journal of Reproduction and Development 2007, 53(3):465-471.
17. Kramer R.E., Rainey W.E., Funkenstein B., Dee A., Simpson E.R., Waterman M.R. Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP. Journal of Biological Chemistry 1984, 259(2):707-713.
18. Lin D., Sugawara T., Strauss J.F., Clark B.J., Stocco D.M., Saenger P., Rogol A., Miller W.L. Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis. Science 1995, 267(5205):1828-1831.
19. Matsuno Y., Adachi T., Koh K.B., Fukata H., Sugimura A., Sakurai K., Shibayama T., Iguchi T., Komiyama M., Mori C. Effect of neonatal exposure to diethylstilbestrol on testicular gene expression in adult mouse: comprehensive analysis with cDNA subtraction method. International Journal of Andrology 2004, 27(2):115-122.
20. Miller W.L. Molecular biology of steroid hormone synthesis. Endocrine Reviews 1988, 9(3):295-318.
21. Nishihara T., Nishikawa J., Kanayama T., Dakeyama F., Saito K., Imagawa M., Takatori S., Kitagawa Y., Hori S., Utsumi H. Estrogenic activities of 517 chemicals by yeast two-hybrid assay. Journal of Health Science 2000, 46(4):282-298.
22. Ohta S., Tabuchi Y., Yanai N., Asano S., Fuse H., Obinata M. Establishment of Leydig cell line, TTE1, from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. Archives of Andrology 2002, 48(1):43-51.
23. Rice D.A., Kirkman M.S., Aitken L.D., Mouw A.R., Schimmer B.P., Parker K.L. Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme. Journal of Biological Chemistry 1990, 265(20):11713-11720.
24. Saunders P.T., Maguire S.M., Gaughan J., Millar M.R. Expression of oestrogen receptor beta (ER beta) in multiple rat tissues visualised by immunohistochemistry. Journal of Endocrinology 1997, 154(3):R13-R16.
25. Song K.H., Lee K., Choi H.S. Endocrine disrupter bisphenol a induces orphan nuclear receptor Nur77 gene expression and steroidogenesis in mouse testicular Leydig cells. Endocrinology 2002, 143(6):2208-2215.
26. Stocco D.M., Clark B.J. Regulation of the acute production of steroids in steroidogenic cells. Endocrine Reviews 1996, 17(3):221-244.
27. Sugawara T., Lin D., Holt J.A., Martin K.O., Javitt N.B., Miller W.L., Strauss J.F. Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity. Biochemistry 1995, 34(39):12506-12512.
28. Toppari J., Larsen J.C., Christiansen P., Giwercman A., Grandjean P., Guillette L.J., Jégou B., Jensen T.K., Jouannet P., Keiding N., Leffers H., McLachlan J.A., Meyer O., Müller J., Rajpert-De Meyts E., Scheike T., Sharpe R.M., Sumpter J., Skakkebæk N.E. Male reproductive health and environmental xenoestrogens. Environmental Health Perspectives 1996, 104(Suppl 4):741-803.
29. Toyama Y., Ohkawa M., Oku R., Maekawa M., Yuasa S. Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat. Journal of Andrology 2001, 22(3):413-423.
30. Tsuchiya M., Inoue K., Matsuda H., Nakamura K., Mizutani T., Miyamoto K., Minegishi T. Expression of steroidogenic acute regulatory protein (StAR) and LH receptor in MA-10 cells. Life Sciences 2003, 73(22):2855-2863.
31. Warita K., Sugawara T., Yue Z.P., Tsukahara S., Mutoh K., Hasegawa Y., Kitagawa H., Mori C., Hoshi N. Progression of the dose-related effects of estrogenic endocrine disruptors, an important factor in declining fertility, differs between the hypothalamo-pituitary axis and reproductive organs of male mice. Journal of Veterinary Medical Science 2006, 68(12):1257-1267.
32. Warita K., Okamoto K., Mutoh K., Hasegawa Y., Yue Z.P., Yokoyama T., Matsumoto Y., Miki T., Takeuchi Y., Kitagawa H., Sugawara T., Hoshi N. Activin A and equine chorionic gonadotropin recover reproductive dysfunction induced by neonatal exposure to an estrogenic endocrine disruptor in adult male mice. Biology of Reproduction 2008, 78(1):59-67.
33. Wolffe A.P., Pruss D. Targeting chromatin disruption: transcription regulators that acetylate histones. Cell 1996, 84(6):817-819.
34. Zimniski S.J., Melner M.H., Puett D. Induction of an estrogen-dependent early steroidogenic lesion in murine Leydig tumor cells. Endocrinology 1985, 116(6):2583-2591.