Roles of transcriptional corepressor RIP140 and coactivator PGC-1α in energy state of chronically infarcted rat hearts and mitochondrial function of cardiomyocytes

Molecular and Cellular Endocrinology

Volumn 362, Issue 1-2, 2012, Pages 11-18

  Chen, Yanfang ^a   Wang, Yuhua ^b   Chen, Jianwen ^a   Chen, Xi ^a   Cao, Weiwei ^a   Chen, Shaorui ^a   Xu, Suowen ^a   Huang, Heqing ^a   Liu, Peiqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Adenovirus; Heart failure; Metabolism; Mitochondrial biogenesis; PGC 1 ; RIP140

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOVIRUS VECTOR; CREATINE PHOSPHATE; ESTROGEN RELATED RECEPTOR ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RECEPTOR INTERACTING PROTEIN 140; TRANSCRIPTION FACTOR NRF1;

ADULT ANIMAL; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOGENESIS; CELL FUNCTION; CONTROLLED STUDY; DISEASE COURSE; ECHOCARDIOGRAPHY; GENE REPRESSION; HEART FAILURE; HEART FUNCTION; HEART HEMODYNAMICS; HEART INFARCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL CULTURE TECHNIQUES; ENERGY METABOLISM; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; HEART VENTRICLES; MALE; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA, HEART; MITOCHONDRIAL TURNOVER; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; NUCLEAR PROTEINS; PHOSPHOCREATINE; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 84865285759     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.03.023     Document Type: Article

References (38)

1. Bernocchi P., Ceconi C., Cargnoni A., Pedersini P., Curello S., Ferrari R. Extraction and assay of creatine phosphate, purine, and pyridine nucleotides in cardiac tissue by reversed-phase high-performance liquid chromatography. Anal. Biochem. 1994, 222:374-379.
2. Cavailles V., Dauvois S., L'Horset F., Lopez G., Hoare S., Kushner P.J., Parker M.G. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J. 1995, 14:3741-3751.
3. Conway M.A., Allis J., Ouwerkerk R., Niioka T., Rajagopalan B., Radda G.K. Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy. Lancet. 1991, 338:973-976.
4. Debevec D., Christian M., Morganstein D., Seth A., Herzog B., Parker M., White R. Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen-related receptor alpha. Mol. Endocrinol. 2007, 21:1581-1592.
5. Ding L., Dong L., Chen X., Zhang L., Xu X., Ferro A., Xu B. Increased expression of integrin-linked kinase attenuates left ventricular remodeling and improves cardiac function after myocardial infarction. Circulation 2009, 120:764-773.
6. Finck B.N., Kelly D.P. Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease. Circulation 2007, 115:2540-2548.
7. Fritah A., Steel J.H., Nichol D., Parker N., Williams S., Price A., Strauss L., Ryder T.A., Mobberley M.A., Poutanen M., Parker M., White R. Elevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac function. Cardiovasc Res. 2010, 86:443-451.
8. Fu J.J., Gao H., Pi R.B., Liu P.Q. An optimized protocol for culture of cardiomyocyte from neonatal rat. Cytotechnology 2005, 49:109-116.
9. Hallberg M., Morganstein D.L., Kiskinis E., Shah K., Kralli A., Dilworth S.M., White R., Parker M.G., Christian M. A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA. Mol. Cell Biol. 2008, 28:6785-6795.
10. Hickson-Bick D.L., Jones C., Buja L.M. Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death. J. Mol. Cell Cardiol. 2008, 44:411-418.
11. Huss J.M., Kelly D.P. Mitochondrial energy metabolism in heart failure: a question of balance. J. Clin. Invest. 2005, 115:547-555.
12. Jager S., Handschin C., St-Pierre J., Spiegelman B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. USA 2007, 104:12017-12022.
13. Kalsi K.K., Smolenski R.T., Pritchard R.D., Khaghani A., Seymour A.M., Yacoub M.H. Energetics and function of the failing human heart with dilated or hypertrophic cardiomyopathy. Eur. J. Clin. Invest. 1999, 29:469-477.
14. Kanamori H., Takemura G., Maruyama R., Goto K., Tsujimoto A., Ogino A., Li L., Kawamura I., Takeyama T., Kawaguchi T., Nagashima K., Fujiwara T., Fujiwara H., Seishima M., Minatoguchi S. Functional significance and morphological characterization of starvation-induced autophagy in the adult heart. Am. J. Pathol. 2009, 174:1705-1714.
15. Kroemer G., Levine B. Autophagic cell death: the story of a misnomer. Nat. Rev. Mol. Cell Biol. 2008, 9:1004-1010.
16. Lai L., Leone T.C., Zechner C., Schaeffer P.J., Kelly S.M., Flanagan D.P., Medeiros D.M., Kovacs A., Kelly D.P. Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2008, 22:1948-1961.
17. Lehman J.J., Barger P.M., Kovacs A., Saffitz J.E., Medeiros D.M., Kelly D.P. Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J. Clin. Invest. 2000, 106:847-856.
18. Lerin C., Rodgers J.T., Kalume D.E., Kim S.H., Pandey A., Puigserver P. GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab. 2006, 3:429-438.
19. Massie B.M., Schaefer S., Garcia J., McKirnan M.D., Schwartz G.G., Wisneski J.A., Weiner M.W., White F.C. Myocardial high-energy phosphate and substrate metabolism in swine with moderate left ventricular hypertrophy. Circulation. 1995, 91:1814-1823.
20. Mizushima N., Yamamoto A., Matsui M., Yoshimori T., Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol. Biol. Cell. 2004, 15:1101-1111.
21. Murray A.J., Cole M.A., Lygate C.A., Carr C.A., Stuckey D.J., Little S.E., Neubauer S., Clarke K. Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart. J. Mol. Cell Cardiol. 2008, 44:694-700.
22. Nakagawa Y., Kuwahara K., Takemura G., Akao M., Kato M., Arai Y., Takano M., Harada M., Murakami M., Nakanishi M., Usami S., Yasuno S., Kinoshita H., Fujiwara M., Ueshima K., Nakao K. P300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. Circ. Res. 2009, 105:746-754.
23. Neubauer S., Horn M., Cramer M., Harre K., Newell J.B., Peters W., Pabst T., Ertl G., Hahn D., Ingwall J.S., Kochsiek K. Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy. Circulation 1997, 96:2190-2196.
24. Paolisso G., Gambardella A., Galzerano D., D'Amore A., Rubino P., Verza M., Teasuro P., Varricchio M., D'Onofrio F. Total-body and myocardial substrate oxidation in congestive heart failure. Metabolism 1994, 43:174-179.
25. Perry S.W., Norman J.P., Barbieri J., Brown E.B., Gelbard H.A. Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques 2011, 50:98-115.
26. Powelka A.M., Seth A., Virbasius J.V., Kiskinis E., Nicoloro S.M., Guilherme A., Tang X., Straubhaar J., Cherniack A.D., Parker M.G., Czech M.P. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J. Clin. Invest. 2006, 116:125-136.
27. Rabinowitz J.D., White E. Autophagy and metabolism. Science 2010, 330:1344-1348.
28. Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005, 434:113-118.
29. Rowe G.C., Jiang A., Arany Z. PGC-1 coactivators in cardiac development and disease. Circ. Res. 2011, 107:825-838.
30. Seth A., Steel J.H., Nichol D., Pocock V., Kumaran M.K., Fritah A., Mobberley M., Ryder T.A., Rowlerson A., Scott J., Poutanen M., White R., Parker M. The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle. Cell Metab. 2007, 6:236-245.
31. Stanley W.C., Recchia F.A., Lopaschuk G.D. Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. 2005, 85:1093-1129.
32. Teyssier C., Ma H., Emter R., Kralli A., Stallcup M.R. Activation of nuclear receptor coactivator PGC-1alpha by arginine methylation. Genes Dev. 2005, 19:1466-1473.
33. Trausch-Azar J., Leone T.C., Kelly D.P., Schwartz A.L. Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway. J. Biol. Chem. 2010, 285:40192-40200.
34. Wareski P., Vaarmann A., Choubey V., Safiulina D., Liiv J., Kuum M., Kaasik A. PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons. J. Biol. Chem. 2009, 284:21379-21385.
35. Ye Y., Gong G., Ochiai K., Liu J., Zhang J. High-energy phosphate metabolism and creatine kinase in failing hearts: a new porcine model. Circulation 2001, 103:1570-1576.
36. Zhang Y., Huypens P., Adamson A.W., Chang J.S., Henagan T.M., Boudreau A., Lenard N.R., Burk D., Klein J., Perwitz N., Shin J., Fasshauer M., Kralli A., Gettys T.W. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha. J. Biol. Chem. 2009, 284:32813-32826.
37. Zhang Z., Teng C.T. Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression. Mol. Cell Endocrinol. 2007, 264:128-141.
38. Zschiedrich I., Hardeland U., Krones-Herzig A., Berriel Diaz M., Vegiopoulos A., Muggenburg J., Sombroek D., Hofmann T.G., Zawatzky R., Yu X., Gretz N., Christian M., White R., Parker M.G., Herzig S. Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression. Blood 2008, 112:264-276.