메뉴 건너뛰기




Volumn 130, Issue 3, 2012, Pages

Identification of epitopes on ADAMTS13 recognized by a panel of monoclonal antibodies with functional or non-functional effects on catalytic activity

Author keywords

ADAMTS13; Epitope mapping; Monoclonal antibody

Indexed keywords

MONOCLONAL ANTIBODY; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

EID: 84865261272     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2012.06.006     Document Type: Article
Times cited : (8)

References (29)
  • 1
    • 47249144803 scopus 로고    scopus 로고
    • Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
    • J.E. Sadler Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura Blood 112 2008 11 18
    • (2008) Blood , vol.112 , pp. 11-18
    • Sadler, J.E.1
  • 2
    • 0035798582 scopus 로고    scopus 로고
    • Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
    • X. Zheng, D. Chung, T.K. Takayama, E.M. Majerus, J.E. Sadler, and K. Fujikawa Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura J Biol Chem 276 2001 41059 41063
    • (2001) J Biol Chem , vol.276 , pp. 41059-41063
    • Zheng, X.1    Chung, D.2    Takayama, T.K.3    Majerus, E.M.4    Sadler, J.E.5    Fujikawa, K.6
  • 3
    • 28344435221 scopus 로고    scopus 로고
    • Cleavage of ultra-large von Willebrand factor by ADAMTS-13 under flow conditions
    • J.F. Dong Cleavage of ultra-large von Willebrand factor by ADAMTS-13 under flow conditions J Thromb Haemost 3 2005 1710 1716
    • (2005) J Thromb Haemost , vol.3 , pp. 1710-1716
    • Dong, J.F.1
  • 4
    • 0042530524 scopus 로고    scopus 로고
    • Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13
    • X. Zheng, K. Nishio, E.M. Majerus, and J.E. Sadler Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13 J Biol Chem 278 2003 30136 30141
    • (2003) J Biol Chem , vol.278 , pp. 30136-30141
    • Zheng, X.1    Nishio, K.2    Majerus, E.M.3    Sadler, J.E.4
  • 5
    • 0142152440 scopus 로고    scopus 로고
    • ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage
    • K. Soejima, M. Matsumoto, K. Kokame, H. Yagi, H. Ishizashi, and H. Maeda ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage Blood 102 2003 3232 3237
    • (2003) Blood , vol.102 , pp. 3232-3237
    • Soejima, K.1    Matsumoto, M.2    Kokame, K.3    Yagi, H.4    Ishizashi, H.5    Maeda, H.6
  • 6
    • 20444454641 scopus 로고    scopus 로고
    • Binding of ADAMTS13 to von Willebrand factor
    • E.M. Majerus, P.J. Anderson, and J.E. Sadler Binding of ADAMTS13 to von Willebrand factor J Biol Chem 280 2005 21773 21778
    • (2005) J Biol Chem , vol.280 , pp. 21773-21778
    • Majerus, E.M.1    Anderson, P.J.2    Sadler, J.E.3
  • 7
    • 23844465898 scopus 로고    scopus 로고
    • The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor
    • J. Ai, P. Smith, S. Wang, P. Zhang, and X.L. Zheng The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor J Biol Chem 280 2005 29428 29434
    • (2005) J Biol Chem , vol.280 , pp. 29428-29434
    • Ai, J.1    Smith, P.2    Wang, S.3    Zhang, P.4    Zheng, X.L.5
  • 8
    • 72949104661 scopus 로고    scopus 로고
    • Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
    • M. Akiyama, S. Takeda, K. Kokame, J. Takagi, and T. Miyata Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor Proc Natl Acad Sci U S A 106 2009 19274 19279
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19274-19279
    • Akiyama, M.1    Takeda, S.2    Kokame, K.3    Takagi, J.4    Miyata, T.5
  • 9
    • 34548834974 scopus 로고    scopus 로고
    • The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow
    • P. Zhang, W. Pan, A.H. Rux, B.S. Sachais, and X.L. Zheng The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow Blood 110 2007 1887 1894
    • (2007) Blood , vol.110 , pp. 1887-1894
    • Zhang, P.1    Pan, W.2    Rux, A.H.3    Sachais, B.S.4    Zheng, X.L.5
  • 11
    • 70350492506 scopus 로고    scopus 로고
    • A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF
    • S. Zanardelli, A.C. Chion, E. Groot, P.J. Lenting, T.A. McKinnon, and M.A. Laffan A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF Blood 114 2009 2819 2828
    • (2009) Blood , vol.114 , pp. 2819-2828
    • Zanardelli, S.1    Chion, A.C.2    Groot, E.3    Lenting, P.J.4    McKinnon, T.A.5    Laffan, M.A.6
  • 12
    • 32944481942 scopus 로고    scopus 로고
    • Analysis on the molecular species and concentration of circulating ADAMTS13 in blood
    • K. Soejima, H. Nakamura, M. Hirashima, W. Morikawa, C. Nozaki, and T. Nakagaki Analysis on the molecular species and concentration of circulating ADAMTS13 in blood J Biochem 139 2006 147 154
    • (2006) J Biochem , vol.139 , pp. 147-154
    • Soejima, K.1    Nakamura, H.2    Hirashima, M.3    Morikawa, W.4    Nozaki, C.5    Nakagaki, T.6
  • 15
    • 79960425069 scopus 로고    scopus 로고
    • Epitope analysis of autoantibodies to ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura
    • Y. Yamaguchi, T. Moriki, A. Igari, T. Nakagawa, H. Wada, and M. Matsumoto Epitope analysis of autoantibodies to ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura Thromb Res 128 2011 169 173
    • (2011) Thromb Res , vol.128 , pp. 169-173
    • Yamaguchi, Y.1    Moriki, T.2    Igari, A.3    Nakagawa, T.4    Wada, H.5    Matsumoto, M.6
  • 17
    • 33746348610 scopus 로고    scopus 로고
    • Novel monoclonal antibody-based enzyme immunoassay for determining plasma levels of ADAMTS13 activity
    • S. Kato, M. Matsumoto, T. Matsuyama, A. Isonishi, H. Hiura, and Y. Fujimura Novel monoclonal antibody-based enzyme immunoassay for determining plasma levels of ADAMTS13 activity Transfusion 46 2006 1444 1452
    • (2006) Transfusion , vol.46 , pp. 1444-1452
    • Kato, S.1    Matsumoto, M.2    Matsuyama, T.3    Isonishi, A.4    Hiura, H.5    Fujimura, Y.6
  • 18
    • 17144408687 scopus 로고    scopus 로고
    • FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay
    • K. Kokame, Y. Nobe, Y. Kokubo, A. Okayama, and T. Miyata FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay Br J Haematol 129 2005 93 100
    • (2005) Br J Haematol , vol.129 , pp. 93-100
    • Kokame, K.1    Nobe, Y.2    Kokubo, Y.3    Okayama, A.4    Miyata, T.5
  • 19
    • 34848826829 scopus 로고    scopus 로고
    • Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains
    • S. Gerhardt, G. Hassall, P. Hawtin, E. McCall, L. Flavell, and C. Minshull Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains J Mol Biol 373 2007 891 902
    • (2007) J Mol Biol , vol.373 , pp. 891-902
    • Gerhardt, S.1    Hassall, G.2    Hawtin, P.3    McCall, E.4    Flavell, L.5    Minshull, C.6
  • 20
    • 38349112018 scopus 로고    scopus 로고
    • High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2)
    • H.S. Shieh, K.J. Mathis, J.M. Williams, R.L. Hills, J.F. Wiese, and T.E. Benson High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2) J Biol Chem 283 2008 1501 1507
    • (2008) J Biol Chem , vol.283 , pp. 1501-1507
    • Shieh, H.S.1    Mathis, K.J.2    Williams, J.M.3    Hills, R.L.4    Wiese, J.F.5    Benson, T.E.6
  • 21
    • 37549037806 scopus 로고    scopus 로고
    • Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
    • L. Mosyak, K. Georgiadis, T. Shane, K. Svenson, T. Hebert, and T. McDonagh Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5 Protein Sci 17 2008 16 21
    • (2008) Protein Sci , vol.17 , pp. 16-21
    • Mosyak, L.1    Georgiadis, K.2    Shane, T.3    Svenson, K.4    Hebert, T.5    McDonagh, T.6
  • 22
    • 2942588403 scopus 로고    scopus 로고
    • Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura
    • C. Klaus, B. Plaimauer, J.D. Studt, F. Dorner, B. Lämmle, and P.M. Mannucci Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura Blood 103 2004 4514 4519
    • (2004) Blood , vol.103 , pp. 4514-4519
    • Klaus, C.1    Plaimauer, B.2    Studt, J.D.3    Dorner, F.4    Lämmle, B.5    Mannucci, P.M.6
  • 23
    • 13844256432 scopus 로고    scopus 로고
    • The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura
    • B.M. Luken, E.A. Turenhout, J.J. Hulstein, J.A. Van Mourik, R. Fijnheer, and J. Voorberg The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura Thromb Haemost 93 2005 267 274
    • (2005) Thromb Haemost , vol.93 , pp. 267-274
    • Luken, B.M.1    Turenhout, E.A.2    Hulstein, J.J.3    Van Mourik, J.A.4    Fijnheer, R.5    Voorberg, J.6
  • 24
    • 33750069427 scopus 로고    scopus 로고
    • Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura
    • B.M. Luken, P.H. Kaijen, E.A. Turenhout, J.A. Kremer Hovinga, J.A. van Mourik, and R. Fijnheer Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura J Thromb Haemost 4 2006 2355 2364
    • (2006) J Thromb Haemost , vol.4 , pp. 2355-2364
    • Luken, B.M.1    Kaijen, P.H.2    Turenhout, E.A.3    Kremer Hovinga, J.A.4    Van Mourik, J.A.5    Fijnheer, R.6
  • 25
    • 33748597666 scopus 로고    scopus 로고
    • Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP
    • B.M. Luken, E.A. Turenhout, P.H. Kaijen, M.J. Greuter, W. Pos, and J.A. van Mourik Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP Thromb Haemost 96 2006 295 301
    • (2006) Thromb Haemost , vol.96 , pp. 295-301
    • Luken, B.M.1    Turenhout, E.A.2    Kaijen, P.H.3    Greuter, M.J.4    Pos, W.5    Van Mourik, J.A.6
  • 26
    • 77949882442 scopus 로고    scopus 로고
    • An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
    • W. Pos, J.T. Crawley, R. Fijnheer, J. Voorberg, D.A. Lane, and B.M. Luken An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF Blood 115 2010 1640 1649
    • (2010) Blood , vol.115 , pp. 1640-1649
    • Pos, W.1    Crawley, J.T.2    Fijnheer, R.3    Voorberg, J.4    Lane, D.A.5    Luken, B.M.6
  • 27
    • 77956824177 scopus 로고    scopus 로고
    • Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
    • X.L. Zheng, H.M. Wu, D. Shang, E. Falls, C.G. Skipwith, and S.R. Cataland Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura Haematologica 95 2010 1555 1562
    • (2010) Haematologica , vol.95 , pp. 1555-1562
    • Zheng, X.L.1    Wu, H.M.2    Shang, D.3    Falls, E.4    Skipwith, C.G.5    Cataland, S.R.6
  • 28
    • 80052964635 scopus 로고    scopus 로고
    • Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain
    • W. Pos, N. Sorvillo, R. Fijnheer, H.B. Feys, P.H. Kaijen, and G. Vidarsson Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain Haematologica 96 2011 1670 1677
    • (2011) Haematologica , vol.96 , pp. 1670-1677
    • Pos, W.1    Sorvillo, N.2    Fijnheer, R.3    Feys, H.B.4    Kaijen, P.H.5    Vidarsson, G.6
  • 29
    • 80155138041 scopus 로고    scopus 로고
    • Novel recombinant glycosylphosphatidylinositol(GPI)-anchored ADAMTS13 and variants for assessment of anti-ADAMTS13 autoantibodies in patients with thrombotic thrombocytopenic purpura
    • D. Li, J. Xiao, M. Paessler, and X.L. Zheng Novel recombinant glycosylphosphatidylinositol(GPI)-anchored ADAMTS13 and variants for assessment of anti-ADAMTS13 autoantibodies in patients with thrombotic thrombocytopenic purpura Thromb Haemost 106 2011 947 958
    • (2011) Thromb Haemost , vol.106 , pp. 947-958
    • Li, D.1    Xiao, J.2    Paessler, M.3    Zheng, X.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.