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Volumn 128, Issue 2, 2011, Pages 169-173

Epitope analysis of autoantibodies to ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura

Author keywords

ADAMTS13; Autoantibody; Phage surface display system; Thrombotic thrombocytopenic purpura; Von Willebrand factor

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN G; PROTEIN G; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

EID: 79960425069     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.03.010     Document Type: Article
Times cited : (30)

References (34)
  • 1
    • 0020428664 scopus 로고
    • Unusually large plasma factor VIII: Von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura
    • J.L. Moake, C.K. Rudy, J.H. Troll, M.J. Weinstein, N.M. Colannino, and J. Azocar Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura N Engl J Med 307 1982 1432 1435 (Pubitemid 13234018)
    • (1982) New England Journal of Medicine , vol.307 , Issue.23 , pp. 1432-1435
    • Moake, J.L.1    Rudy, C.K.2    Troll, J.H.3
  • 3
    • 0032569840 scopus 로고    scopus 로고
    • Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura
    • DOI 10.1056/NEJM199811263392203
    • H.M. Tsai, and E.C. Lian Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura N Engl J Med 339 1998 1585 1594 (Pubitemid 28536133)
    • (1998) New England Journal of Medicine , vol.339 , Issue.22 , pp. 1585-1594
    • Tsai, H.-M.1    Lian, E.C.-Y.2
  • 5
    • 0035885972 scopus 로고    scopus 로고
    • Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family
    • K. Fujikawa, H. Suzuki, B. McMullen, and D. Chung Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family Blood 98 2001 1662 1666
    • (2001) Blood , vol.98 , pp. 1662-1666
    • Fujikawa, K.1    Suzuki, H.2    McMullen, B.3    Chung, D.4
  • 6
    • 0035885962 scopus 로고    scopus 로고
    • Partial amino acid sequence of purified von Willebrand factor-cleaving protease
    • H.E. Gerritsen, R. Robles, B. Lammle, and M. Furlan Partial amino acid sequence of purified von Willebrand factor-cleaving protease Blood 98 2001 1654 1661
    • (2001) Blood , vol.98 , pp. 1654-1661
    • Gerritsen, H.E.1    Robles, R.2    Lammle, B.3    Furlan, M.4
  • 7
    • 0034759807 scopus 로고    scopus 로고
    • A novel human metalloprotease synthesized in the liver and secreted into the blood: Possibly, the von Willebrand factor-cleaving protease?
    • K. Soejima, N. Mimura, M. Hirashima, H. Maeda, T. Hamamoto, and T. Nakagaki A novel human metalloprotease synthesized in the liver and secreted into the Blood: possibly, the von Willebrand factor-cleaving protease? J Biochem 130 2001 475 480 (Pubitemid 33021590)
    • (2001) Journal of Biochemistry , vol.130 , Issue.4 , pp. 475-480
    • Soejima, K.1    Mimura, N.2    Hirashima, M.3    Maeda, H.4    Hamamoto, T.5    Nakagaki, T.6    Nozaki, C.7
  • 8
    • 0035798582 scopus 로고    scopus 로고
    • Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
    • X. Zheng, D. Chung, T.K. Takayama, E.M. Majerus, J.E. Sadler, and K. Fujikawa Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura J Biol Chem 276 2001 41059 41063
    • (2001) J Biol Chem , vol.276 , pp. 41059-41063
    • Zheng, X.1    Chung, D.2    Takayama, T.K.3    Majerus, E.M.4    Sadler, J.E.5    Fujikawa, K.6
  • 10
    • 0042530524 scopus 로고    scopus 로고
    • Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13
    • DOI 10.1074/jbc.M305331200
    • X. Zheng, K. Nishio, E.M. Majerus, and J.E. Sadler Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13 J Biol Chem 278 2003 30136 30141 (Pubitemid 36962406)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.32 , pp. 30136-30141
    • Zheng, X.1    Nishio, K.2    Majerus, E.M.3    Sadler, J.E.4
  • 11
    • 23844465898 scopus 로고    scopus 로고
    • The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor
    • DOI 10.1074/jbc.M505513200
    • J. Ai, P. Smith, S. Wang, P. Zhang, and X.L. Zheng The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor J Biol Chem 280 2005 29428 29434 (Pubitemid 41177015)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.33 , pp. 29428-29434
    • Ai, J.1    Smith, P.2    Wang, S.3    Zhang, P.4    Zheng, X.L.5
  • 13
    • 28844490990 scopus 로고    scopus 로고
    • Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions
    • DOI 10.1182/blood-2005-05-2029
    • Z. Tao, Y. Peng, L. Nolasco, S. Cal, C. Lopez-Otin, and R. Li Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions Blood 106 2005 4139 4145 (Pubitemid 41775919)
    • (2005) Blood , vol.106 , Issue.13 , pp. 4139-4145
    • Tao, Z.1    Peng, Y.2    Nolasco, L.3    Cal, S.4    Lopez-Otin, C.5    Li, R.6    Moake, J.L.7    Lopez, J.A.8    Dong, J.-F.9
  • 14
    • 34548834974 scopus 로고    scopus 로고
    • The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow
    • DOI 10.1182/blood-2007-04-083329
    • P. Zhang, W. Pan, A.H. Rux, B.S. Sachais, and X.L. Zheng The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow Blood 110 2007 1887 1894 (Pubitemid 47443901)
    • (2007) Blood , vol.110 , Issue.6 , pp. 1887-1894
    • Zhang, P.1    Pan, W.2    Rux, A.H.3    Sachais, B.S.4    Zheng, X.L.5
  • 15
    • 0142183462 scopus 로고    scopus 로고
    • Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura
    • DOI 10.1182/blood-2003-05-1616
    • F. Scheiflinger, P. Knobl, B. Trattner, B. Plaimauer, G. Mohr, and M. Dockal Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura Blood 102 2003 3241 3243 (Pubitemid 37314762)
    • (2003) Blood , vol.102 , Issue.9 , pp. 3241-3243
    • Scheiflinger, F.1    Knobl, P.2    Trattner, B.3    Plaimauer, B.4    Mohr, G.5    Dockal, M.6    Dorner, F.7    Rieger, M.8
  • 16
    • 33746650438 scopus 로고    scopus 로고
    • Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo
    • DOI 10.1111/j.1538-7836.2006.02025.x
    • S.G. Shelat, P. Smith, J. Ai, and X.L. Zheng Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo J Thromb Haemost 4 2006 1707 1717 (Pubitemid 44144797)
    • (2006) Journal of Thrombosis and Haemostasis , vol.4 , Issue.8 , pp. 1707-1717
    • Shelat, S.G.1    Smith, P.2    Ai, J.3    Zheng, X.L.4
  • 18
    • 70350006842 scopus 로고    scopus 로고
    • IgG-subclass distribution of anti-ADAMTS13 antibodies in patients with acquired thrombotic thrombocytopenic purpura
    • S. Ferrari, G.C. Mudde, M. Rieger, A. Veyradier, J.A. Hovinga, and F. Scheiflinger IgG-subclass distribution of anti-ADAMTS13 antibodies in patients with acquired thrombotic thrombocytopenic purpura J Thromb Haemost 7 2009 1703 1710
    • (2009) J Thromb Haemost , vol.7 , pp. 1703-1710
    • Ferrari, S.1    Mudde, G.C.2    Rieger, M.3    Veyradier, A.4    Hovinga, J.A.5    Scheiflinger, F.6
  • 19
    • 2542490269 scopus 로고    scopus 로고
    • Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura
    • DOI 10.1182/blood-2003-11-4035
    • X.L. Zheng, R.M. Kaufman, L.T. Goodnough, and J.E. Sadler Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura Blood 103 2004 4043 4049 (Pubitemid 38685342)
    • (2004) Blood , vol.103 , Issue.11 , pp. 4043-4049
    • Zheng, X.L.1    Kaufman, R.M.2    Goodnough, L.T.3    Sadler, J.E.4
  • 21
    • 77949903692 scopus 로고    scopus 로고
    • Survival and relapse in patients with thrombotic thrombocytopenic purpura
    • quiz 1662
    • J.A. Hovinga, S.K. Vesely, D.R. Terrell, B. Lammle, and J.N. George Survival and relapse in patients with thrombotic thrombocytopenic purpura Blood 115 2010 1500 1511 quiz 1662
    • (2010) Blood , vol.115 , pp. 1500-1511
    • Hovinga, J.A.1    Vesely, S.K.2    Terrell, D.R.3    Lammle, B.4    George, J.N.5
  • 23
    • 2942588403 scopus 로고    scopus 로고
    • Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura
    • DOI 10.1182/blood-2003-12-4165
    • C. Klaus, B. Plaimauer, J.D. Studt, F. Dorner, B. Lammle, and P.M. Mannucci Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura Blood 103 2004 4514 4519 (Pubitemid 38745978)
    • (2004) Blood , vol.103 , Issue.12 , pp. 4514-4519
    • Klaus, C.1    Plaimauer, B.2    Studt, J.-D.3    Dorner, F.4    Lammle, B.5    Mannucci, P.M.6    Scheiflinger, F.7
  • 24
    • 13844256432 scopus 로고    scopus 로고
    • The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura
    • DOI 10.1160/TH04-05-0301
    • B.M. Luken, E.A. Turenhout, J.J. Hulstein, J.A. Mourik, R. Fijnheer, and J. Voorberg The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura Thromb Haemost 93 2005 267 274 (Pubitemid 40253731)
    • (2005) Thrombosis and Haemostasis , vol.93 , Issue.2 , pp. 267-274
    • Luken, B.M.1    Turenhout, E.A.M.2    Hulstein, J.J.J.3    Van Mourik, J.A.4    Fijnheer, R.5    Voorberg, J.6
  • 25
    • 28844502248 scopus 로고    scopus 로고
    • Enzymatically active ADAMTS13 variants are not inhibited by anti-ADAMTS13 autoantibodies: A novel therapeutic strategy?
    • DOI 10.1074/jbc.M504919200
    • W. Zhou, L. Dong, D. Ginsburg, E.E. Bouhassira, and H.M. Tsai Enzymatically active ADAMTS13 variants are not inhibited by anti-ADAMTS13 autoantibodies: a novel therapeutic strategy? J Biol Chem 280 2005 39934 39941 (Pubitemid 41779128)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 39934-39941
    • Zhou, W.1    Dong, L.2    Ginsburg, D.3    Bouhdssira, E.E.4    Tsai, H.-M.5
  • 26
    • 33750069427 scopus 로고    scopus 로고
    • Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura
    • DOI 10.1111/j.1538-7836.2006.02164.x
    • B.M. Luken, P.H. Kaijen, E.A. Turenhout, J.A. Hovinga, J.A. Mourik, and R. Fijnheer Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura J Thromb Haemost 4 2006 2355 2364 (Pubitemid 44575429)
    • (2006) Journal of Thrombosis and Haemostasis , vol.4 , Issue.11 , pp. 2355-2364
    • Luken, B.M.1    Kaijen, P.H.P.2    Turenhout, E.A.M.3    Kremer Hovinga, J.A.4    Van Mourik, J.A.5    Fijnheer, R.6    Voorberg, J.7
  • 27
    • 33748597666 scopus 로고    scopus 로고
    • Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP
    • DOI 10.1160/TH06-03-0135
    • B.M. Luken, E.A. Turenhout, P.H. Kaijen, M.J. Greuter, W. Pos, and J.A. Mourik Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP Thromb Haemost 96 2006 295 301 (Pubitemid 44377812)
    • (2006) Thrombosis and Haemostasis , vol.96 , Issue.3 , pp. 295-301
    • Luken, B.M.1    Turenhout, E.A.M.2    Kaijen, P.H.P.3    Greuter, M.J.4    Pos, W.5    Van Mourik, J.A.6    Fijnheer, R.7    Voorberg, J.8
  • 28
    • 77956824177 scopus 로고    scopus 로고
    • Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
    • X.L. Zheng, H.M. Wu, D. Shang, E. Falls, C.G. Skipwith, and S.R. Cataland Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura Haematologica 95 2010 1555 1561
    • (2010) Haematologica , vol.95 , pp. 1555-1561
    • Zheng, X.L.1    Wu, H.M.2    Shang, D.3    Falls, E.4    Skipwith, C.G.5    Cataland, S.R.6
  • 30
    • 17144408687 scopus 로고    scopus 로고
    • FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay
    • DOI 10.1111/j.1365-2141.2005.05420.x
    • K. Kokame, Y. Nobe, Y. Kokubo, A. Okayama, and T. Miyata FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay Br J Haematol 29 2005 93 100 (Pubitemid 40524057)
    • (2005) British Journal of Haematology , vol.129 , Issue.1 , pp. 93-100
    • Kokame, K.1    Nobe, Y.2    Kokubo, Y.3    Okayama, A.4    Miyata, T.5
  • 31
    • 33746348610 scopus 로고    scopus 로고
    • Novel monoclonal antibody-based enzyme immunoassay for determining plasma levels of ADAMTS13 activity
    • DOI 10.1111/j.1537-2995.2006.00914.x
    • S. Kato, M. Matsumoto, T. Matsuyama, A. Isonishi, H. Hiura, and Y. Fujimura Novel monoclonal antibody-based enzyme immunoassay for determining plasma levels of ADAMTS13 activity Transfusion 46 2006 1444 1452 (Pubitemid 44117975)
    • (2006) Transfusion , vol.46 , Issue.8 , pp. 1444-1452
    • Kato, S.1    Matsumoto, M.2    Matsuyama, T.3    Isonishi, A.4    Hiura, H.5    Fujimura, Y.6
  • 32
    • 77949882442 scopus 로고    scopus 로고
    • An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
    • W. Pos, J.T. Crawley, R. Fijnheer, J. Voorberg, D.A. Lane, and B.M. Luken An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF Blood 115 2010 1640 1649
    • (2010) Blood , vol.115 , pp. 1640-1649
    • Pos, W.1    Crawley, J.T.2    Fijnheer, R.3    Voorberg, J.4    Lane, D.A.5    Luken, B.M.6
  • 33
    • 72949104661 scopus 로고    scopus 로고
    • Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
    • M. Akiyama, S. Takeda, K. Kokame, J. Takagi, and T. Miyata Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor Proc Natl Acad Sci USA 106 2009 19274 19279
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19274-19279
    • Akiyama, M.1    Takeda, S.2    Kokame, K.3    Takagi, J.4    Miyata, T.5
  • 34
    • 77950414918 scopus 로고    scopus 로고
    • Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor
    • S.Y. Jin, C.G. Skipwith, and X.L. Zheng Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor Blood 115 2010 2300 2310
    • (2010) Blood , vol.115 , pp. 2300-2310
    • Jin, S.Y.1    Skipwith, C.G.2    Zheng, X.L.3


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