Validation of Aedes aegypti Aag-2 cells as a model for insect immune studies

Parasites and Vectors

Volumn 5, Issue 1, 2012, Pages

  Barletta, Ana Beatriz Ferreira ^a,b   Silva, Maria Clara L Nascimento ^c   Sorgine, Marcos H Ferreira ^a,b  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular INCT EM CNPq   (Brazil)

^c Trifermed   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; STAT PROTEIN; TOLL LIKE RECEPTOR; ZYMOSAN;

AEDES AEGYPTI; ANIMAL CELL; ARTICLE; CELL LINEAGE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENTEROBACTER CLOACAE; GENE EXPRESSION; IMMUNOSTIMULATION; INNATE IMMUNITY; INSECT CELL; MICROCOCCUS LUTEUS; MOLECULAR MODEL; NONHUMAN; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PROVOCATION TEST; SINDBIS VIRUS;

AEDES; ANIMALS; CELL LINE; ENTEROBACTER CLOACAE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MICROCOCCUS LUTEUS; PHAGOCYTOSIS; REPRODUCIBILITY OF RESULTS; SINDBIS VIRUS; ZYMOSAN;

EID: 84865258561     PISSN: None     EISSN: 17563305     Source Type: Journal    
DOI: 10.1186/1756-3305-5-148     Document Type: Article

References (51)

1. Dengue and haemorragic fever http://www.who.int/mediacentre/factsheets/ fs117/en/
2. Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces. WHO, Book Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces World Health Organization, City 1998 46
3. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. De Gregorio E, Spellman PT, Tzou P, Rubin GM, Lemaitre B, EMBO J 2002 21 2568 2579 10.1093/emboj/21.11.2568 12032070 (Pubitemid 34619373)
4. The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila. Dostert C, Jouanguy E, Irving P, Troxler L, Galiana-Arnoux D, Hetru C, Hoffmann JA, Imler JL, Nat Immunol 2005 6 946 953 16086017 (Pubitemid 43090450)
5. Activation of the Drosophila innate immunity by the toll and IMD pathways. Tanji T, Seikagaku 2006 78 413 417 16780113
6. Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogaster. Tanji T, Hu X, Weber AN, Ip YT, Mol Cell Biol 2007 27 4578 4588 10.1128/MCB.01814-06 17438142 (Pubitemid 46906578)
7. Regulators of the Toll and Imd pathways in the Drosophila innate immune response. Tanji T, Ip YT, Trends Immunol 2005 26 193 198 10.1016/j.it.2005.02. 006 15797509 (Pubitemid 41556856)
8. Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants. Tzou P, Reichhart JM, Lemaitre B, Proc Natl Acad Sci U S A 2002 99 2152 2157 10.1073/pnas.042411999 11854512 (Pubitemid 34169030)
9. Drosophila innate immunity: an evolutionary perspective. Hoffmann JA, Reichhart JM, Nat Immunol 2002 3 121 126 10.1038/ni0202-121 11812988 (Pubitemid 34141441)
10. The Aedes aegypti toll pathway controls dengue virus infection. Xi Z, Ramirez JL, Dimopoulos G, PLoS Pathog 2008 4 1000098 10.1371/journal.ppat. 1000098 18604274
11. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Lemaitre B, Reichhart JM, Hoffmann JA, Proc Natl Acad Sci U S A 1997 94 14614 14619 10.1073/pnas.94.26.14614 9405661 (Pubitemid 28041422)
12. Overview of innate immunity in Drosophila. Kim T, Kim YJ, J Biochem Mol Biol 2005 38 121 127 10.5483/BMBRep.2005.38.2.121 15826489 (Pubitemid 43026213)
13. The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections. Ferrandon D, Imler JL, Hetru C, Hoffmann JA, Nat Rev Immunol 2007 7 862 874 10.1038/nri2194 17948019 (Pubitemid 350006241)
14. Genome sequence of Aedes aegypti, a major arbovirus vector. Nene V, Wortman JR, Lawson D, Haas B, Kodira C, Tu ZJ, Loftus B, Xi Z, Megy K, Grabherr M, et al. Science 2007 316 1718 1723 10.1126/science.1138878 17510324 (Pubitemid 46988541)
15. Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Waterhouse RM, Kriventseva EV, Meister S, Xi Z, Alvarez KS, Bartholomay LC, Barillas-Mury C, Bian G, Blandin S, Christensen BM, et al. Science 2007 316 1738 1743 10.1126/science.1139862 17588928 (Pubitemid 46988547)
16. Establishment of four strains of cells from insect tissues grown in vitro. Grace TD, Nature 1962 195 788 789 10.1038/195788a0 13900940
17. RNA interference, arthropod-borne viruses, and mosquitoes. Sanchez-Vargas I, Travanty EA, Keene KM, Franz AW, Beaty BJ, Blair CD, Olson KE, Virus Res 2004 102 65 74 10.1016/j.virusres.2004.01.017 15068882 (Pubitemid 38447251)
18. Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae. Levashina EA, Moita LF, Blandin S, Vriend G, Lagueux M, Kafatos FC, Cell 2001 104 709 718 10.1016/S0092-8674(01)00267-7 11257225 (Pubitemid 32241021)
19. Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytosis, endocytosis and infection of West Nile virus. Mizutani T, Kobayashi M, Eshita Y, Shirato K, Kimura T, Ako Y, Miyoshi H, Takasaki T, Kurane I, Kariwa H, et al. Insect Mol Biol 2003 12 491 499 10.1046/j.1365-2583.2003.00435.x 12974954 (Pubitemid 37207556)
20. Phagocytosis in mosquito immune responses. Blandin SA, Levashina EA, Immunol Rev 2007 219 8 16 10.1111/j.1600-065X.2007.00553.x 17850478 (Pubitemid 47390006)
21. Genomic RNAi screening in Drosophila S2 cells: what have we learned about host-pathogen interactions? Cherry S, Curr Opin Microbiol 2008 11 262 270 10.1016/j.mib.2008.05.007 18539520
22. Non-specific antiviral response detected in RNA-treated cultured cells of the sandfly, Lutzomyia longipalpis. Pitaluga AN, Mason PW, Traub-Cseko YM, Dev Comp Immunol 2008 32 191 197 10.1016/j.dci.2007.06.008 17706772 (Pubitemid 350180081)
23. Wolbachia infections in Anopheles gambiae cells: transcriptomic characterization of a novel host-symbiont interaction. Hughes GL, Ren X, Ramirez JL, Sakamoto JM, Bailey JA, Jedlicka AE, Rasgon JL, PLoS Pathog 2011 7 1001296 10.1371/journal.ppat.1001296 21379333
24. Regulation of transcription of the Aedes albopictus cecropin A1 gene: A role for p38 mitogen-activated protein kinase. Moon AE, Walker AJ, Goodbourn S, Insect Biochem Mol Biol 2011 41 628 636 10.1016/j.ibmb.2011.04.001 21501684
25. RNA silencing of dengue virus type 2 replication in transformed C6/36 mosquito cells transcribing an inverted-repeat RNA derived from the virus genome. Adelman ZN, Sanchez-Vargas I, Travanty EA, Carlson JO, Beaty BJ, Blair CD, Olson KE, J Virol 2002 76 12925 12933 10.1128/JVI.76.24.12925-12933.2002 12438618 (Pubitemid 35386976)
26. Isolation of a Singh's Aedes albopictus cell clone sensitive to Dengue and Chikungunya viruses. Igarashi A, J Gen Virol 1978 40 531 544 10.1099/0022-1317-40-3-531 690610 (Pubitemid 9014927)
27. Morphogenesis of Sindbis virus in three subclones of Aedes albopictus (mosquito) cells. Miller ML, Brown DT, J Virol 1992 66 4180 4190 1602541
28. Cell cultures derived from larvae of Aedes albopictus (Skuse) Aedes aegypti (L). Singh KR, Curr Sci 1967 36 506 508
29. Characterization of an endogenous gene expressed in Aedes aegypti using an orally infectious recombinant Sindbis virus. Cheng LL, Bartholomay LC, Olson KE, Lowenberger C, Vizioli J, Higgs S, Beaty BJ, Christensen BM, J Insect Sci 2001 1 10 15455070
30. C6/36 Aedes albopictus cells have a dysfunctional antiviral RNA interference response. Brackney DE, Scott JC, Sagawa F, Woodward JE, Miller NA, Schilkey FD, Mudge J, Wilusz J, Olson KE, Blair CD, Ebel GD, PLoS Negl Trop Dis 2010 4 856 10.1371/journal.pntd.0000856 21049065
31. Growth of arboviruses in primary tissue culture of Aedes aegypti embryos. Peleg J, Am J Trop Med Hyg 1968 17 219 223 4869110
32. Dengue virus inhibits immune responses in Aedes aegypti cells. Sim S, Dimopoulos G, PLoS One 2010 5 10678 10.1371/journal.pone.0010678 20502529
33. Exploration of mosquito immunity using cells in culture. Fallon AM, Sun D, Insect Biochem Mol Biol 2001 31 263 278 10.1016/S0965-1748(00)00146-6 11167096 (Pubitemid 32194782)
34. Immunity proteins from mosquito cell lines include three defensin A isoforms from Aedes aegypti and a defensin D from Aedes albopictus. Gao Y, Hernandez VP, Fallon AM, Insect Mol Biol 1999 8 311 318 10.1046/j.1365-2583. 1999.83119.x 10469248 (Pubitemid 29449715)
35. REL1, a homologue of Drosophila dorsal, regulates toll antifungal immune pathway in the female mosquito Aedes aegypti. Shin SW, Kokoza V, Bian G, Cheon HM, Kim YJ, Raikhel AS, J Biol Chem 2005 280 16499 16507 10.1074/jbc.M500711200 15722339 (Pubitemid 40616781)
36. Phenoloxidase activity of hemocytes derived from Penaeus monodon and Macrobrachium rosenbergii. Sung HH, Chang HJ, Her CH, Chang JC, Song YL, J Invertebr Pathol 1998 71 26 33 10.1006/jipa.1997.4703 9446734 (Pubitemid 128352146)
37. RNA interference modulates replication of dengue virus in Drosophila melanogaster cells. Mukherjee S, Hanley KA, BMC Microbiol 2010 10 127 10.1186/1471-2180-10-127 20420715
38. Isolation of a fragment homologous to the rp49 constitutive gene of Drosophila in the Neotropical malaria vector Anopheles aquasalis (Diptera: Culicidae). Gentile C, Lima JB, Peixoto AA, Mem Inst Oswaldo Cruz 2005 100 545 547 16302065 (Pubitemid 41626654)
39. An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense. Souza-Neto JA, Sim S, Dimopoulos G, Proc Natl Acad Sci U S A 2009 106 17841 17846 10.1073/pnas.0905006106 19805194
40. Comparison of dengue virus type 2-specific small RNAs from RNA interference-competent and -incompetent mosquito cells. Scott JC, Brackney DE, Campbell CL, Bondu-Hawkins V, Hjelle B, Ebel GD, Olson KE, Blair CD, PLoS Negl Trop Dis 2010 4 848 10.1371/journal.pntd.0000848 21049014
41. In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila. Nicolas E, Reichhart JM, Hoffmann JA, Lemaitre B, J Biol Chem 1998 273 10463 10469 10.1074/jbc.273.17.10463 9553105 (Pubitemid 28227656)
42. Transgenic alteration of Toll immune pathway in the female mosquito Aedes aegypti. Bian G, Shin SW, Cheon HM, Kokoza V, Raikhel AS, Proc Natl Acad Sci U S A 2005 102 13568 13573 10.1073/pnas.0502815102 16157887 (Pubitemid 41420889)
43. Characterization of three alternatively spliced isoforms of the Rel/NF-kappa B transcription factor Relish from the mosquito Aedes aegypti. Shin SW, Kokoza V, Ahmed A, Raikhel AS, Proc Natl Acad Sci U S A 2002 99 9978 9983 10.1073/pnas.162345999 12119421 (Pubitemid 34831158)
44. The role of NF-kappaB factor REL2 in the Aedes aegypti immune response. Antonova Y, Alvarez KS, Kim YJ, Kokoza V, Raikhel AS, Insect Biochem Mol Biol 2009 39 303 314 10.1016/j.ibmb.2009.01.007 19552893
45. The host defense of Drosophila melanogaster. Lemaitre B, Hoffmann J, Annu Rev Immunol 2007 25 697 743 10.1146/annurev.immunol.25.022106.141615 17201680 (Pubitemid 46697922)
46. Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae. Meister S, Kanzok SM, Zheng XL, Luna C, Li TR, Hoa NT, Clayton JR, White KP, Kafatos FC, Christophides GK, Zheng L, Proc Natl Acad Sci U S A 2005 102 11420 11425 10.1073/pnas.0504950102 16076953 (Pubitemid 41153835)
47. The entomopathogenic fungus Beauveria bassiana activate toll and JAK-STAT pathway-controlled effector genes and anti-dengue activity in Aedes aegypti. Dong Y, Morton JC, Ramirez JL, Souza-Neto JA, Dimopoulos G, Insect Biochem Mol Biol 2012 42 126 132 10.1016/j.ibmb.2011.11.005 22198333
48. Profiling infection responses in the haemocytes of the mosquito, Aedes aegypti. Bartholomay LC, Mayhew GF, Fuchs JF, Rocheleau TA, Erickson SM, Aliota MT, Christensen BM, Insect Mol Biol 2007 16 761 776 10.1111/j.1365-2583.2007. 00773.x 18093005 (Pubitemid 350290896)
49. Sindbis virus induces transport processes and alters expression of innate immunity pathway genes in the midgut of the disease vector, Aedes aegypti. Sanders HR, Foy BD, Evans AM, Ross LS, Beaty BJ, Olson KE, Gill SS, Insect Biochem Mol Biol 2005 35 1293 1307 10.1016/j.ibmb.2005.07.006 16203210 (Pubitemid 41412222)
50. Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections. Nehme NT, Quintin J, Cho JH, Lee J, Lafarge MC, Kocks C, Ferrandon D, PLoS One 2011 6 14743 10.1371/journal.pone.0014743 21390224
51. Virus entry by endocytosis. Mercer J, Schelhaas M, Helenius A, Annu Rev Biochem 2010 79 803 833 10.1146/annurev-biochem-060208-104626 20196649