ADAMTS5: A new player in the vascular field

American Journal of Pathology

Volumn 181, Issue 3, 2012, Pages 743-745

  Nissinen, Liisa ^a,b   Khri, Veli Matti ^a,b  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMTS1 PROTEIN; AGGRECANASE 2; BEVACIZUMAB; GELATINASE B; PLACENTAL GROWTH FACTOR; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; STROMELYSIN; THROMBOSPONDIN 1; VASCULOTROPIN;

ANGIOGENESIS; BREAST CANCER; CANCER INHIBITION; COLORECTAL CANCER; DOWN REGULATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; LUNG NON SMALL CELL CANCER; MELANOMA; METASTASIS; NONHUMAN; NOTE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; TUMOR GROWTH; UPREGULATION;

ADAM PROTEINS; ANGIOGENESIS INHIBITORS; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; METALLOENDOPEPTIDASES;

EID: 84865230972     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.07.002     Document Type: Note

References (25)

1. J. Folkman Angiogenesis Annu Rev Med 57 2006 1 18
2. N. Ferrara VEGF as a therapeutic target in cancer Oncology 69 Suppl 3 2005 11 16
3. V. Baeriswyl, G. Christofori The angiogenic switch in carcinogenesis Semin Cancer Biol 19 2009 329 337
4. K. Kessenbrock, V. Plaks, Z. Werb Matrix metalloproteinases: regulators of the tumor microenvironment Cell 141 2010 52 67
5. S. Kumar, S. Sharghi-Namini, N. Rao, R. Ge ADAMTS5 functions as an anti-angiogenic and anti-tumorigenic protein independent of its proteoglycanase activity Am J Pathol 181 2012 1056 1068
6. N. Rocks, G. Paulissen, M. El Hour, F. Quesada, C. Crahay, M. Gueders, J.M. Foidart, A. Noel, D. Cataldo Emerging roles of ADAM and ADAMTS metalloproteinases in cancer Biochimie 90 2008 369 379
7. S. Porter, I.M. Clark, L. Kevorkian, D.R. Edwards The ADAMTS metalloproteinases Biochem J 386 2005 15 27
8. Y.J. Liu, Y. Xu, Q. Yu Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively Oncogene 25 2006 2452 2467
9. S. Porter, P.N. Span, F.C. Sweep, V.C. Tjan-Heijnen, C.J. Pennington, T.X. Pedersen, M. Johnsen, L.R. Lund, J. Rømer, D.R. Edwards ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma Int J Cancer 118 2006 1241 1247
10. G.E. Lind, K. Kleivi, G.I. Meling, M.R. Teixeira, E. Thiis-Evensen, T.O. Rognum, R.A. Lothe ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis Cell Oncol 28 2006 259 272
11. A. Moncada-Pazos, A.J. Obaya, M.F. Fraga, C.G. Viloria, G. Capell, M. Gausachs, M. Esteller, C. Lpez-Otn, S. Cal The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer J Cell Sci 122 2009 2906 2913
12. M.L. Iruela-Arispe, D. Carpizo, A. Luque ADAMTS1: a matrix metalloprotease with angioinhibitory properties Ann N Y Acad Sci 995 2003 183 190
13. N.V. Lee, M. Sato, D.S. Annis, J.A. Loo, L. Wu, D.F. Mosher, M.L. Iruela-Arispe ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2 EMBO J 25 2006 5270 5283
14. B.H. Koo, D.M. Coe, L.J. Dixon, R.P. Somerville, C.M. Nelson, L.W. Wang, M.E. Young, D.J. Lindner, S.S. Apte ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells Am J Pathol 176 2010 1494 1504
15. M. El Hour, A. Moncada-Pazos, S. Blacher, A. Masset, S. Cal, S. Berndt, J. Detilleux, L. Host, A.J. Obaya, C. Maillard, J.M. Foidart, F. Ectors, A. Noel, C. Lopez-Otin Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis Oncogene 29 2010 3025 3032
16. Y.P. Hsu, C.A. Staton, N. Cross, D.J. Buttle Anti-angiogenic properties of ADAMTS-4 in vitro Int J Exp Pathol 93 2012 70 77
17. S.S. Glasson, R. Askew, B. Sheppard, B. Carito, T. Blanchet, H.L. Ma, C.R. Flannery, D. Peluso, K. Kanki, Z. Yang, M.K. Majumdar, E.A. Morris Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis Nature 434 2005 644 648
18. N.A. Cross, S. Chandrasekharan, N. Jokonya, A. Fowles, F.C. Hamdy, D.J. Buttle, C.L. Eaton The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican Prostate 63 2005 269 275
19. A. Stokes, J. Joutsa, R. Ala-aho, M. Pitchers, C.J. Pennington, C. Martin, D.J. Premachandra, Y. Okada, J. Peltonen, R. Grnman, H.A. James, D.R. Edwards, V.M. Khri Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma Clin Cancer Res 16 2010 2022 2035
20. K. Demircan, E. Gunduz, M. Gunduz, L.B. Beder, S. Hirohata, H. Nagatsuka, B. Cengiz, M.Z. Cilek, N. Yamanaka, K. Shimizu, Y. Ninomiya Increased mRNA expression of ADAMTS metalloproteinases in metastatic foci of head and neck cancer Head Neck 31 2009 793 801
21. Y.H. Kim, H.C. Lee, S.Y. Kim, Y.I. Yeom, K.J. Ryu, B.H. Min, D.H. Kim, H.J. Son, P.L. Rhee, J.J. Kim, J.C. Rhee, H.C. Kim, H.K. Chun, W.M. Grady, Y.S. Kim Epigenomic analysis of aberrantly methylated genes in colorectal cancer identifies genes commonly affected by epigenetic alterations Ann Surg Oncol 18 2011 2338 2347
22. S. Sharghi-Namini, H. Fan, K.N. Sulochana, P. Potturi, W. Xiang, Y.S. Chong, Z. Wang, H. Yang, R. Ge The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor Biochem Biophys Res Commun 371 2008 215 219
23. P. Saharinen, L. Eklund, K. Pulkki, P. Bono, K. Alitalo VEGF and angiopoietin signaling in tumor angiogenesis and metastasis Trends Mol Med 17 2011 347 362
24. L.G. Presta, H. Chen, S.J. O'Connor, V. Chisholm, Y.G. Meng, L. Krummen, M. Winkler, N. Ferrara Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders Cancer Res 57 1997 4593 4599
25. F. Shojaei Anti-angiogenesis therapy in cancer: current challenges and future perspectives Cancer Lett 320 2012 130 137