Canonical Wnt signaling is required for Panax notoginseng saponin-mediated attenuation of the RANKL/OPG ratio in bone marrow stromal cells during osteogenic differentiation

Phytomedicine

Volumn 19, Issue 11, 2012, Pages 1029-1034

  Chen, Bin ^a   Li, Xue Dong ^a   Liu, Dong Xin ^a   Wang, Hu ^a   Xie, Peng ^a   Liu, Zhao Yong ^a   Hou, Guo Qing ^a   Chang, Bo ^a   Du, Shi Xin ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Bone marrow stromal cells; Osteoprotegerin (OPG); Panax notoginseng saponins; Receptor activator of NF B ligand (RANKL); Wnt catenin signaling pathway

Indexed keywords

BETA CATENIN; CYCLIN D1; DICKKOPF 1 PROTEIN; GINSENOSIDE RB 1; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RG 1; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PANAX NOTOGINSENG EXTRACT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; BONE DEVELOPMENT; BONE MARROW CELL; CANONICAL ANALYSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; MALE; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; PANAX NOTOGINSENG; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKELETON; STROMA CELL; WNT SIGNALING PATHWAY;

ANIMALS; BONE RESORPTION; CALCIUM; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; GENE EXPRESSION REGULATION; GINSENOSIDES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; OSTEOPROTEGERIN; PANAX NOTOGINSENG; PPAR GAMMA; RANK LIGAND; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; WNT PROTEINS; WNT SIGNALING PATHWAY;

PANAX NOTOGINSENG;

EID: 84865221770     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.06.002     Document Type: Article

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