-
1
-
-
77954249308
-
Two to tango: Regulation of mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, Galy B, &, Camaschella C, (2010) Two to tango: regulation of mammalian iron metabolism. Cell 142, 24-38.
-
(2010)
Cell
, vol.142
, pp. 24-38
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Galy, B.3
Camaschella, C.4
-
2
-
-
70450214396
-
The role of hepcidin in iron metabolism
-
Nemeth E, &, Ganz T, (2009) The role of hepcidin in iron metabolism. Acta Haematol 122, 78-86.
-
(2009)
Acta Haematol
, vol.122
, pp. 78-86
-
-
Nemeth, E.1
Ganz, T.2
-
3
-
-
69949088488
-
Hepcidin, the iron watcher
-
Viatte L, &, Vaulont S, (2009) Hepcidin, the iron watcher. Biochimie 91, 1223-1228.
-
(2009)
Biochimie
, vol.91
, pp. 1223-1228
-
-
Viatte, L.1
Vaulont, S.2
-
4
-
-
0034284595
-
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
-
Krause A, Neitz S, Mägert HJ, Schulz A, Forssmann WG, Schulz-Knappe P, &, Adermann K, (2000) LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett 480, 147-150.
-
(2000)
FEBS Lett
, vol.480
, pp. 147-150
-
-
Krause, A.1
Neitz, S.2
Mägert, H.J.3
Schulz, A.4
Forssmann, W.G.5
Schulz-Knappe, P.6
Adermann, K.7
-
5
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, &, Ganz T, (2001) Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 276, 7806-7810.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
6
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, Leroyer P, Turlin B, Brissot P, &, Loréal O, (2001) A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 276, 7811-7819.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
Leroyer, P.4
Turlin, B.5
Brissot, P.6
Loréal, O.7
-
7
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, &, Vaulont S, (2001) Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 98, 8780-8785.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
Beaumont, C.4
Grandchamp, B.5
Kahn, A.6
Vaulont, S.7
-
8
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas G, Bennoun M, Porteu A, Mativet S, Beaumont C, Grandchamp B, Sirito M, Sawadogo M, Kahn A, &, Vaulont S, (2002) Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA 99, 4596-4601.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Porteu, A.3
Mativet, S.4
Beaumont, C.5
Grandchamp, B.6
Sirito, M.7
Sawadogo, M.8
Kahn, A.9
Vaulont, S.10
-
9
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, Alberti F, Girelli D, Christakis J, Loukopoulos D, &, Camaschella C, (2003) Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 33, 21-22.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
Alberti, F.4
Girelli, D.5
Christakis, J.6
Loukopoulos, D.7
Camaschella, C.8
-
10
-
-
1342322891
-
Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat
-
Yeh KY, Yeh M, &, Glass J, (2004) Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat. Am J Physiol Gastrointest Liver Physiol 286, G385-G394.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.286
-
-
Yeh, K.Y.1
Yeh, M.2
Glass, J.3
-
11
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, &, Kaplan J, (2004) Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306, 2090-2093.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
Ganz, T.7
Kaplan, J.8
-
12
-
-
34250865977
-
The molecular mechanism of hepcidin-mediated ferroportin down-regulation
-
De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, &, Kaplan J, (2007) The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell 18, 2569-2578.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2569-2578
-
-
De Domenico, I.1
Ward, D.M.2
Langelier, C.3
Vaughn, M.B.4
Nemeth, E.5
Sundquist, W.I.6
Ganz, T.7
Musci, G.8
Kaplan, J.9
-
13
-
-
48149090865
-
The hepcidin-binding site on ferroportin is evolutionarily conserved
-
De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, &, Kaplan J, (2008) The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metab 8, 146-156.
-
(2008)
Cell Metab
, vol.8
, pp. 146-156
-
-
De Domenico, I.1
Nemeth, E.2
Nelson, J.M.3
Phillips, J.D.4
Ajioka, R.S.5
Kay, M.S.6
Kushner, J.P.7
Ganz, T.8
Ward, D.M.9
Kaplan, J.10
-
14
-
-
79953061479
-
Understanding the structure/activity relationships of the iron regulatory peptide hepcidin
-
Clark RJ, Tan CC, Preza GC, Nemeth E, Ganz T, &, Craik DJ, (2011) Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chem Biol 18, 336-343.
-
(2011)
Chem Biol
, vol.18
, pp. 336-343
-
-
Clark, R.J.1
Tan, C.C.2
Preza, G.C.3
Nemeth, E.4
Ganz, T.5
Craik, D.J.6
-
15
-
-
84055190801
-
Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload
-
Preza GC, Ruchala P, Pinon R, Ramos E, Qiao B, Peralta MA, Sharma S, Waring A, Ganz T, &, Nemeth E, (2011) Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. J Clin Invest 121, 4880-4888.
-
(2011)
J Clin Invest
, vol.121
, pp. 4880-4888
-
-
Preza, G.C.1
Ruchala, P.2
Pinon, R.3
Ramos, E.4
Qiao, B.5
Peralta, M.A.6
Sharma, S.7
Waring, A.8
Ganz, T.9
Nemeth, E.10
-
16
-
-
67651087324
-
The molecular basis of hepcidin-resistant hereditary hemochromatosis
-
Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, &, Nemeth E, (2009) The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood 114, 437-443.
-
(2009)
Blood
, vol.114
, pp. 437-443
-
-
Fernandes, A.1
Preza, G.C.2
Phung, Y.3
De Domenico, I.4
Kaplan, J.5
Ganz, T.6
Nemeth, E.7
-
17
-
-
69949128102
-
Hepcidin revisited, disulfide connectivity, dynamics, and structure
-
Jordan JB, Poppe L, Haniu M, Arvedson T, Syed R, Li V, Kohno H, Kim H, Schnier PD, Harvey TS, et al. (2009) Hepcidin revisited, disulfide connectivity, dynamics, and structure. J Biol Chem 284, 24155-24167.
-
(2009)
J Biol Chem
, vol.284
, pp. 24155-24167
-
-
Jordan, J.B.1
Poppe, L.2
Haniu, M.3
Arvedson, T.4
Syed, R.5
Li, V.6
Kohno, H.7
Kim, H.8
Schnier, P.D.9
Harvey, T.S.10
-
18
-
-
77951896065
-
Oxidative folding of hepcidin at acidic pH
-
Zhang J, Diamond S, Arvedson T, Sasu BJ, &, Miranda LP, (2010) Oxidative folding of hepcidin at acidic pH. Biopolymers 94, 257-264.
-
(2010)
Biopolymers
, vol.94
, pp. 257-264
-
-
Zhang, J.1
Diamond, S.2
Arvedson, T.3
Sasu, B.J.4
Miranda, L.P.5
-
19
-
-
18144366586
-
Expression and preparation of recombinant hepcidin in Escherichia coli
-
Zhang H, Yuan Q, Zhu Y, &, Ma R, (2005) Expression and preparation of recombinant hepcidin in Escherichia coli. Protein Expr Purif 41, 409-416.
-
(2005)
Protein Expr Purif
, vol.41
, pp. 409-416
-
-
Zhang, H.1
Yuan, Q.2
Zhu, Y.3
Ma, R.4
-
20
-
-
47249126331
-
Production of biologically active forms of recombinant hepcidin, the iron-regulatory hormone
-
Gagliardo B, Faye A, Jaouen M, Deschemin JC, Canonne-Hergaux F, Vaulont S, &, Sari MA, (2008) Production of biologically active forms of recombinant hepcidin, the iron-regulatory hormone. FEBS J 275, 3793-3803.
-
(2008)
FEBS J
, vol.275
, pp. 3793-3803
-
-
Gagliardo, B.1
Faye, A.2
Jaouen, M.3
Deschemin, J.C.4
Canonne-Hergaux, F.5
Vaulont, S.6
Sari, M.A.7
-
21
-
-
42649107142
-
Iron regulatory and bactericidal properties of human recombinant hepcidin expressed in Pichia pastoris
-
Koliaraki V, Marinou M, Samiotaki M, Panayotou G, Pantopoulos K, &, Mamalaki A, (2008) Iron regulatory and bactericidal properties of human recombinant hepcidin expressed in Pichia pastoris. Biochimie 90, 726-735.
-
(2008)
Biochimie
, vol.90
, pp. 726-735
-
-
Koliaraki, V.1
Marinou, M.2
Samiotaki, M.3
Panayotou, G.4
Pantopoulos, K.5
Mamalaki, A.6
-
22
-
-
0014374019
-
A method for the complete S sulfonation of cysteine residues in proteins
-
Chan WW, (1968) A method for the complete S sulfonation of cysteine residues in proteins. Biochemistry 7, 4247-4254.
-
(1968)
Biochemistry
, vol.7
, pp. 4247-4254
-
-
Chan, W.W.1
-
23
-
-
0031052016
-
Expression, purification and characterization of recombinant human proinsulin
-
Cowley DJ, &, Mackin RB, (1997) Expression, purification and characterization of recombinant human proinsulin. FEBS Lett 402, 124-130.
-
(1997)
FEBS Lett
, vol.402
, pp. 124-130
-
-
Cowley, D.J.1
MacKin, R.B.2
-
24
-
-
69249216709
-
Suppression of protein aggregation by L-arginine
-
Lange C, &, Rudolph R, (2009) Suppression of protein aggregation by L-arginine. Curr Pharm Biotechnol 10, 408-414.
-
(2009)
Curr Pharm Biotechnol
, vol.10
, pp. 408-414
-
-
Lange, C.1
Rudolph, R.2
-
25
-
-
69249215476
-
To be excluded or to bind, that is the question: Arginine effects on proteins
-
Nakakido M, Kudou M, Arakawa T, &, Tsumoto K, (2009) To be excluded or to bind, that is the question: arginine effects on proteins. Curr Pharm Biotechnol 10, 415-420.
-
(2009)
Curr Pharm Biotechnol
, vol.10
, pp. 415-420
-
-
Nakakido, M.1
Kudou, M.2
Arakawa, T.3
Tsumoto, K.4
-
26
-
-
30144432585
-
The N-terminus of hepcidin is essential for its interaction with ferroportin: Structure-function study
-
Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, &, Ganz T, (2006) The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood 107, 328-333.
-
(2006)
Blood
, vol.107
, pp. 328-333
-
-
Nemeth, E.1
Preza, G.C.2
Jung, C.L.3
Kaplan, J.4
Waring, A.J.5
Ganz, T.6
-
27
-
-
84858823076
-
Synthesis and biological activity of mouse hepcidin peptide analogs containing three disulfide bridges: Manual and microwave-assisted solid-phase peptide synthesis
-
Khemtemourian L, Desbenoit N, Mahesh P, Chatterjee S, Deschemin JC, Vaulont S, Tomas A, Sari MA, &, Artaud I, (2012) Synthesis and biological activity of mouse hepcidin peptide analogs containing three disulfide bridges: manual and microwave-assisted solid-phase peptide synthesis. Protein Pept Lett 19, 219-227.
-
(2012)
Protein Pept Lett
, vol.19
, pp. 219-227
-
-
Khemtemourian, L.1
Desbenoit, N.2
Mahesh, P.3
Chatterjee, S.4
Deschemin, J.C.5
Vaulont, S.6
Tomas, A.7
Sari, M.A.8
Artaud, I.9
-
28
-
-
36148996891
-
Folding of conotoxins: Formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides
-
Bulaj G, &, Olivera BM, (2008) Folding of conotoxins: formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides. Antioxid Redox Signal 10, 141-155.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 141-155
-
-
Bulaj, G.1
Olivera, B.M.2
-
29
-
-
73749087228
-
Cyclotides: Macrocyclic peptides with applications in drug design and agriculture
-
Craik DJ, Mylne JS, &, Daly NL, (2010) Cyclotides: macrocyclic peptides with applications in drug design and agriculture. Cell Mol Life Sci 67, 9-16.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 9-16
-
-
Craik, D.J.1
Mylne, J.S.2
Daly, N.L.3
-
30
-
-
0036783412
-
Distinguishing foldable proteins from nonfolders: When and how do they differ?
-
Sosnick TR, Berry RS, Colubri A, &, Fernández A, (2002) Distinguishing foldable proteins from nonfolders: when and how do they differ? Proteins 49, 15-23.
-
(2002)
Proteins
, vol.49
, pp. 15-23
-
-
Sosnick, T.R.1
Berry, R.S.2
Colubri, A.3
Fernández, A.4
-
31
-
-
33645521792
-
Protein aggregation and its consequences for human disease
-
Dobson CM, (2006) Protein aggregation and its consequences for human disease. Protein Pept Lett 13, 219-227.
-
(2006)
Protein Pept Lett
, vol.13
, pp. 219-227
-
-
Dobson, C.M.1
-
32
-
-
1942534142
-
Facile preparation of disulfide-bridged peptides using the polymer-supported oxidant CLEAR-OX
-
Darlak K, Wiegandt Long D, Czerwinski A, Darlak M, Valenzuela F, Spatola AF, &, Barany G, (2004) Facile preparation of disulfide-bridged peptides using the polymer-supported oxidant CLEAR-OX. J Pept Res 63, 303-312.
-
(2004)
J Pept Res
, vol.63
, pp. 303-312
-
-
Darlak, K.1
Wiegandt Long, D.2
Czerwinski, A.3
Darlak, M.4
Valenzuela, F.5
Spatola, A.F.6
Barany, G.7
-
33
-
-
67650474557
-
Click chemistry and bioorthogonal reactions: Unprecedented selectivity in the labeling of biological molecules
-
Best MD, (2009) Click chemistry and bioorthogonal reactions: unprecedented selectivity in the labeling of biological molecules. Biochemistry 48, 6571-6584.
-
(2009)
Biochemistry
, vol.48
, pp. 6571-6584
-
-
Best, M.D.1
-
34
-
-
0000096835
-
Click chemistry: Diverse chemical function from a few good reactions
-
Kolb HC, Finn MG, &, Sharpless KB, (2001) Click chemistry: diverse chemical function from a few good reactions. Angew Chem Int Ed Engl 40, 2004-2021.
-
(2001)
Angew Chem Int Ed Engl
, vol.40
, pp. 2004-2021
-
-
Kolb, H.C.1
Finn, M.G.2
Sharpless, K.B.3
-
35
-
-
84862007363
-
Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT
-
Ross SL, Tran L, Winters A, Lee KJ, Plewa C, Foltz I, King C, Miranda LP, Allen J, Beckman H, et al. (2012) Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. Cell Metab 15, 905-917.
-
(2012)
Cell Metab
, vol.15
, pp. 905-917
-
-
Ross, S.L.1
Tran, L.2
Winters, A.3
Lee, K.J.4
Plewa, C.5
Foltz, I.6
King, C.7
Miranda, L.P.8
Allen, J.9
Beckman, H.10
|