Sec61β controls sensitivity to platinum-containing chemotherapeutic agents through modulation of the copper- transporting ATPase ATP7A

Molecular Pharmacology

Volumn 82, Issue 3, 2012, Pages 510-520

  Abada, Paolo B ^a   Larson, Christopher A ^a   Manorek, Gerald ^a   Adams, Preston ^a   Howell, Stephen B ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE 7A; ANTINEOPLASTIC METAL COMPLEX; ATOX1 PROTEIN; CARBOPLATIN; CHAPERONE; CISPLATIN; COPPER; CTR1 PROTEIN; CTR2 PROTEIN; DOXORUBICIN; ETOPOSIDE; MEMBRANE PROTEIN; OXALIPLATIN; PACLITAXEL; SEC61 BETA PROTEIN; TRANSLOCON; UNCLASSIFIED DRUG; VINCRISTINE;

ARTICLE; CANCER CELL CULTURE; CELLULAR ACCUMULATION; CELLULAR DISTRIBUTION; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOTOXICITY; DECONVOLUTION MICROSCOPY; DRUG ACCUMULATION; DRUG MECHANISM; DRUG SENSITIVITY; DRUG TRANSPORT; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID RAFT; MICROSCOPY; MODULATION; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATASES; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; COPPER; DRUG RESISTANCE, NEOPLASM; FEMALE; HOMEOSTASIS; HUMANS; MEMBRANE PROTEINS; ORGANOPLATINUM COMPOUNDS; OVARIAN NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 84865207156     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.079822     Document Type: Article

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