Pd-catalyzed benzylic C-H amidation with benzyl alcohols in water: A strategy to construct quinazolinones

Journal of Organic Chemistry

Volumn 77, Issue 16, 2012, Pages 7046-7051

  Hikawa, Hidemasa ^a   Ino, Yukari ^a   Suzuki, Hideharu ^a   Yokoyama, Yuusaku ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDATION; BENZYL ALCOHOL; BENZYLIC; DOMINO REACTIONS; HYDROXYL GROUPS; N-BENZYLATION; PALLADIUM-CATALYZED; QUINAZOLINONES;

REACTION KINETICS;

CATALYSIS;

1 METHYL 2 TOLYLQUINAZOLIN 4(3H) ONE; 2 (3 METHOXYPHENYL)QUINAZOLIN 4(3H) ONE; 2 (4 ETHYLPHENYL)QUINAZOLIN 4(3H) ONE; 2 (4 METHOXYPHENYL)QUINAZOLIN 4(3H) ONE; 2 3 TOLYLQUINAZOLIN 4(3H) ONE; 2 4 TOLYLQUINAZOLIN 4(3H) ONE; 3 METHYL 2 PHENYLQUINAZOLIN 4(3H) ONE; 3 METHYL 2 TOLYLQUINAZOLIN 4(3H) ONE; 5 FLUORO 2 PHENYLQUINAZOLIN 4(3H) ONE; 6 FLUORO 2 PHENYLQUINAZOLIN 4(3H) ONE; 7 METHYL 2 PHENYLQUINAZOLIN 4(3H) ONE; BENZYL ALCOHOL; PALLADIUM; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

AMIDATION; ARTICLE; BENZYLATION; CATALYSIS; DEHYDROGENATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND;

BENZAMIDES; BENZYL ALCOHOLS; CARBON; CATALYSIS; HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PALLADIUM; QUINAZOLINONES; STEREOISOMERISM; WATER;

EID: 84865204040     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo301282n     Document Type: Article

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