A new Mycobacterium tuberculosis smooth colony reduces growth inside human macrophages and represses PDIM Operon gene expression. Does an heterogeneous population exist in intracellular mycobacteria?

Microbial Pathogenesis

Volumn 53, Issue 3-4, 2012, Pages 135-146

  Giovannini, Daniela ^a   Cappelli, Giulia ^b   Jiang, Lina ^a,c,d   Castilletti, Concetta ^e   Colone, Alessia ^a   Serafino, Annalucia ^b   Wannenes, Francesca ^a   Giacò, Luciano ^c   Quintiliani, Gianluca ^c   Fraziano, Maurizio ^c   Nepravishta, Ridvan ^c   Colizzi, Vittorio ^c   Mariani, Francesca ^a  

^a CNR   (Italy)

^b INSTITUTE OF TRANSLATIONAL PHARMACOLOGY   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d JILIN UNIVERSITY   (China)

^e NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

Author keywords

Capsule; Colony phenotype; Human macrophages infection; MDM; MTB; Mycobacterium tuberculosis; PDIM; Q rt RT PCR; Virulence

Indexed keywords

BACTERIAL ENZYME; DENDRITIC CELL LYSOSOME ASSOCIATED MEMBRANE PROTEIN; ETHAMBUTOL; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 27; ISONIAZID; PHTHIOCEROL DIMYCOCEROSATES; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM COLONY; BACTERIUM ISOLATION; BIOFILM; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HELY GENE; HOST CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; LEX A GENE; LIPID ANALYSIS; LIPID COMPOSITION; MACROPHAGE; MPRA GENE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OPERON; PCA GENE; PHAGOCYTOSIS; PHAGOLYSOSOME; PHENOTYPE; PRIORITY JOURNAL; RECA GENE; SIGA GENE; SIGB GENE; SIGE GENE; SIGF GENE; SIGG GENE; SIGI GENE; SIGJ GENE; SIGL GENE; SIGM GENE; UPREGULATION;

BACTERIAL PROTEINS; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; INTERFERONS; INTERLEUKIN-12; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS; OPERON; TUBERCULOSIS;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 84865195284     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2012.06.002     Document Type: Article

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