Suppression of lipopolysaccharide-induced upregulation of toll-like receptor 4 by emodin in mouse proximal tubular epithelial cells

Molecular Medicine Reports

Volumn 6, Issue 3, 2012, Pages 493-500

  Zhu, Xiao Ling ^a   Wang, Yong Jun ^a   Yang, Ya Zhen ^a   Yang, Ru Chun ^a   Zhu, Bin ^a   Zhang, Ying Hua ^a   Lin, Yi ^a   Lu, Ying ^a   Li, Xiao Feng ^b   O'Byrne, Kevin T ^b  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Emodin; Interleukin 6; Lipopolysaccharide; Toll like receptor 4; Tubular epithelial cells; Tumor necrosis factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYTOKERATIN; EMODIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VIMENTIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; CELLS, CULTURED; EMODIN; EPITHELIAL CELLS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; KIDNEY TUBULES, PROXIMAL; LIPOPOLYSACCHARIDES; MALE; MICE; PROTEIN KINASE INHIBITORS; RHEUM; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84865193034     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.960     Document Type: Article

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