Tracking Sphingosine Metabolism and Transport in Sphingolipidoses: NPC1 Deficiency as a Test Case

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Volumn 13, Issue 9, 2012, Pages 1234-1243

  Blom, Tomas ^a   Li, Zaiguo ^b   Bittman, Robert ^b   Somerharju, Pentti ^a   Ikonen, Elina ^a,c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

Author keywords

Acid ceramidase; Acid sphingomyelinase; Late endosome lysosome; Low density lipoprotein; Niemann Pick type C1; Sphingolipids; Sphingosine

Indexed keywords

ACID CERAMIDASE; CARBON; CERAMIDE; LOW DENSITY LIPOPROTEIN; NIEMANN PICK TYPE C1 PROTEIN; PROTEIN; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOSINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID DEGRADATION; LIPID METABOLISM; LIPID STORAGE; LIPID TRANSPORT; LIPOGENESIS; NIEMANN PICK DISEASE; PRIORITY JOURNAL;

ANIMALS; CARRIER PROTEINS; CELL LINE, TUMOR; CERAMIDES; CHO CELLS; CRICETINAE; CRICETULUS; ENDOSOMES; HUMANS; LIPOPROTEINS, LDL; LYSOSOMES; MEMBRANE GLYCOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SPHINGOLIPIDOSES; SPHINGOMYELINS; SPHINGOSINE;

EID: 84865191217     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2012.01379.x     Document Type: Article

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