Cholesterol Overload Promotes Morphogenesis of a Niemann-Pick C (NPC)-like Compartment Independent of Inhibition of NPC1 or HE1/NPC2 Function

Journal of Biological Chemistry

Volumn 276, Issue 49, 2001, Pages 46414-46421

  Frolov, Andrey ^a   Srivastava, Kalpana ^a   Daphna Iken, Dorit ^a   Traub, Linton M ^b   Schaffer, Jean E ^a   Ory, Daniel S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; DISEASES; GENES; PROTEINS;

PHENOCOPIES;

CHOLESTEROL;

CELL PROTEIN; CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; PROTEIN NPC1; PROTEIN NPC2; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; AMPHOTERICIN B; CARRIER PROTEIN; CHOLESTEROL ESTER; EPIDIDYMAL SECRETORY PROTEIN 14.6; GLYCOPROTEIN; MEMBRANE PROTEIN; NPC1 PROTEIN, HUMAN; PRIMER DNA;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL SELECTION; CHO CELL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ENDOSOME; GENE IDENTIFICATION; GENE MUTATION; GENETIC SCREENING; HUMAN; INHIBITION KINETICS; LYSOSOME; MEMBRANE VESICLE; NEIEMANN PICK C DISEASE; NIEMANN PICK DISEASE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; ANIMAL; GENETICS; HAMSTER; METABOLISM; MORPHOGENESIS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

AMPHOTERICIN B; ANIMAL; BASE SEQUENCE; CARRIER PROTEINS; CELL COMPARTMENTATION; CHO CELLS; CHOLESTEROL; CHOLESTEROL ESTERS; DNA PRIMERS; GLYCOPROTEINS; HAMSTERS; MEMBRANE GLYCOPROTEINS; MORPHOGENESIS; NIEMANN-PICK DISEASES; RECEPTORS, LDL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035824522     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108099200     Document Type: Article

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