KIOM-79 protects AGE-induced retinal pericyte apoptosis via inhibition of NF-kappaB activation in vitro and in VIVO

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Kim, Junghyun ^a   Kim, Chan Sik ^a   Sohn, Eunjin ^a   Lee, Yun Mi ^a   Jo, Kyuhyung ^a   Kim, Jin Sook ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; BOVINE SERUM ALBUMIN; EUPHORBIA EXTRACT; GLUCOSE; GLYCYRRHIZA EXTRACT; HEMOGLOBIN A1C; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 2; MAGNOLIA EXTRACT; PROTEIN BAX; PUERARIA EXTRACT; TUMOR NECROSIS FACTOR ALPHA;

ACELLULAR CAPILLARY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; BODY WEIGHT; CELL CULTURE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COW; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; EUPHORBIA; GLUCOSE BLOOD LEVEL; GLYCYRRHIZA; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MAGNOLIACEAE; MALE; NONHUMAN; PERICYTE; PLANT ROOT; PROTEIN EXPRESSION; PUERARIA; RAT; RETINA BLOOD VESSEL; RETINA CAPILLARY; ZUCKER DIABETIC FATTY RAT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; DIABETIC RETINOPATHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION END PRODUCTS, ADVANCED; MALE; NF-KAPPA B; PERICYTES; PLANT EXTRACTS; RATS; SERUM ALBUMIN, BOVINE;

EID: 84865165518     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043591     Document Type: Article

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