KIOM-79 inhibits LPS-induced iNOS gene expression by blocking NF-κB/Rel and p38 kinase activation in murine macrophages

Journal of Ethnopharmacology

Volumn 108, Issue 1, 2006, Pages 38-45

  Jeon, Young Jin ^a   Li, Mei Hong ^a   Lee, Kun Yeong ^b   Kim, Jin Sook ^c   You, Ho Jin ^a   Lee, Seog Ki ^a   Sohn, Hong Moon ^a   Choi, Sang Joon ^a   Koh, Jae Woong ^a   Chang, In Youb ^a  

^a Chosun University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

iNOS; KIOM 79; Macrophages; NF B Rel; p38 kinase

Indexed keywords

ANTIINFLAMMATORY AGENT; BACTERIUM LIPOPOLYSACCHARIDE; EUPHORBIA PEKINENSIS EXTRACT; GLYCYRRHIZA URALENSIS EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KIOM 79; MAGNOLIA OFFICINALIS EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PLANT EXTRACT; PUERARIA LOBATA EXTRACT; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASSAY; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EUPHORBIA PEKINENSIS; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GLYCYRRHIZA URALENSIS; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MAGNOLIA OFFICINALIS; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN EXPRESSION; PUERARIA LOBATA; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; ENZYME ACTIVATION; EUPHORBIA; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCYRRHIZA URALENSIS; LIPOPOLYSACCHARIDES; MACROPHAGES; MAGNOLIA; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHYTOTHERAPY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-REL;

EUPHORBIA PEKINENSIS; GLYCYRRHIZA URALENSIS; MAGNOLIA OFFICINALIS; MURINAE; PUERARIA MONTANA VAR. LOBATA;

EID: 33745910745     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.04.007     Document Type: Article

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