Probing water-protein contacts in a MMP-12/CGS27023A complex by nuclear magnetic resonance spectroscopy

Journal of Biomolecular NMR

Volumn 53, Issue 2, 2012, Pages 85-92

  Kovacs, Helena ^a   Agback, Tatiana ^b   Isaksson, Johan ^c  

^a BRUKER BIOSPIN AG   (Switzerland)

^b MEDIVIR AB   (Sweden)

^c UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Hydration; Metalloproteases; MMP 12; NMR; Protein water interactions; X filtering

Indexed keywords

CARBON; CGS 27023A; MACROPHAGE ELASTASE; NITROGEN; NITROGEN 15; WATER;

ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; MEAN RESIDENCE TIME; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; ROTATING FRAME OVERHAUSER EFFECT SPECTROSCOPY; THREE DIMENSIONAL IMAGING;

HUMANS; HYDROXAMIC ACIDS; MATRIX METALLOPROTEINASE 12; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEASE INHIBITORS; PROTEIN CONFORMATION; PYRAZINES; SULFONAMIDES; WATER;

EID: 84865163025     PISSN: 09252738     EISSN: 15735001     Source Type: Journal    
DOI: 10.1007/s10858-012-9624-7     Document Type: Article

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